<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10411

Description LADA_0F07162g1_1
SequenceMDADWRSTLSNQERSKYITELAQILAQISQVNGGDRGNFNLEKLKKTAEQFEKNLYASSSSKDLYLDSMRKRIAAMDTARKKAIANVQQNSSNAQSRHDVSTMTNQQMQQQMQMQQRQQQQQQQQAPPSHYPPGSNNVNSQMFFNQQAKLRQQAAQQLRGGIPRNAPVSNNAARPQLTPQQQQLINEMKGAEIPRELLQRIPNLPPGVNTWQKVTELAQQKRLGPKDLQIAKQVYQMHQQIVFKSRLQQVNANNRGPPQGRPNSRVPSAGPGSQAHQGQSALQQPQQPQPHQPQPQMQQPQIVQQSQPQQMPMGQPTQAQTQEVPNVLNRLNQIFTPAEQKALYENGKKLIADLQRTNRLPAVLTPQQQAIYIKKYINQMALKKLQAARNQMGTANASSQQATVPPVSGTGVPQMSQFMPNSGGSQANLAARRPYSGANSNINAFNENPTASELQGPPQNMEQTVLSQPQPQGQVPTQSQTGSQVPGQSQPPPKFSLPRPTEQDLMVLRRISAEIQKSHLRLSNITNQISQEQKQSIRNKLQLNRQLFTNVDSFIPTLYMITRNEENVRQLLQIRMLTKEITEHASRGIFIVPPEVVDKVIFRYQKYYEFIKDQVLRRHQQIIAARQQQQQQQQQQTQPTQQTQHAPQTQQVQQVQQQQTHPRTASQQVDPTFNQQRIQGSFQQIQQQMQMRQHQQHQQQKAQQFTSQIDNWPRPASAKTAEGDPGLMPHSAPETLRATTSGVDFLNSPELLNAKLSPQQGGLSPAKKQAQMRKKMTLKQASNQGTPSAVMPSSTPAPGTGMGPVVSSRTGTPRVANVGLASVSPMATKAVTANQSPSPKSIPNNVGPSGPVSNQYKEDEEILKKMVVRKNDVISRFKRRQDILRNSAVDLFLCCLGESLGVSDDQVELINSIPQEVVDQVNGAGKKVANKPAAQRLKDQEYANVSIKDNRIVFATNSPVGNYKPDATSFGNREVSSIFRDVYGTTDLTTFSFGNSNLTSGSRGTKRNAPDSENSPNISPASSAVMSDSKKIKFDSPEDLYFSAPAEEVKKEFTKDALAGNAEDSKIWDWSFWDTS
Length1076
PositionTail
OrganismLachancea dasiensis CBS 10888
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.05
Grand average of hydropathy-0.874
Instability index60.80
Isoelectric point9.95
Molecular weight120015.28
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10411
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     140.36|      27|      29|     329|     355|       1
---------------------------------------------------------------------------
  274-  297 (41.10/12.40)	QAHQ..GQSALQQ.P..QQ.PQPHQPQPQM
  298-  320 (30.37/ 7.17)	QQ.....PQIVQQSQ.pQQ.MPMGQPTQAQ
  341-  368 (30.77/ 7.37)	KALYENGKKLIADLQrtNR.LPAVLTP.QQ
  676-  700 (38.12/10.95)	QRIQGSFQQIQQQMQ..MRqHQQHQ...QQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.65|      20|      20|     620|     639|       2
---------------------------------------------------------------------------
  622-  642 (37.60/12.73)	IIAARQQQQ.QQ.QQQQTQP...tQQ
  643-  668 (28.05/ 7.24)	TQHAPQTQQvQQvQQQQTHPrtasQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     167.47|      32|      32|     133|     164|       3
---------------------------------------------------------------------------
  101-  134 (50.61/22.00)	STMTNQQMQQQMQMQQR.QQQQQQQQAP..P..S.......hypPG
  135-  168 (53.97/24.06)	SNNVNSQMFFNQQAKLR.QQAAQQLRGG.IP..R........naPV
  169-  207 (33.99/11.80)	SNNAARPQLTPQQ.....QQLINEMKGAeIP..RellqripnlpPG
  236-  263 (28.90/ 8.68)	......QMHQQIVFKSRlQQVNANNRGP..PqgR..........PN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.46|      11|      15|     510|     521|       5
---------------------------------------------------------------------------
  510-  521 (14.99/14.40)	RISAEiQKSHLR
  528-  538 (19.47/12.67)	QISQE.QKQSIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     171.78|      26|      26|     449|     474|       6
---------------------------------------------------------------------------
  405-  428 (38.89/14.44)	PPVSG...TGVPQ.MSQFM.PNSGG.SQAN
  449-  474 (49.58/20.48)	PTASEL..QGPPQNMEQTV.LSQPQ.PQGQ
  476-  496 (29.00/ 8.84)	PTQSQTgsQVPGQ........SQPP.PKFS
  764-  786 (28.04/ 8.30)	SPAKK...QA..Q.MRKKMtLKQAS.NQGT
  792-  814 (26.28/ 7.30)	P..SST..PAPGTGMGPVV.SSRTGtPR..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.41|      27|      31|     905|     934|       7
---------------------------------------------------------------------------
  905-  934 (37.33/32.97)	DQvELIN.SIPQEVVdqVNGAGKKVAN.KPAA
  939-  967 (40.08/23.76)	DQ.EYANvSIKDNRI..VFATNSPVGNyKPDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.98|      15|      15|     558|     572|       8
---------------------------------------------------------------------------
  558-  572 (24.77/19.29)	LYMITRN..EENVRQLL
  574-  590 (19.20/13.13)	IRMLTKEitEHASRGIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.63|      16|      26|     996|    1011|      14
---------------------------------------------------------------------------
  996- 1011 (27.59/16.33)	SNLTSGSRGTKRNAPD
 1023- 1038 (27.04/15.87)	SAVMSDSKKIKFDSPE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10411 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AMDTARKKAIANVQQNSSNAQSRHDVSTMTNQQMQQQMQMQQRQQQQQQQQAPPSHYPPGSNNVNSQMFFNQQAKLRQQAAQQLRGGIPRNAPVSNNAARPQLTPQQQQLINEMKGAEIPRELLQRIPNLPPGVNTWQKVTELAQQKRLGPKDLQIA
2) IIAARQQQQQQQQQQTQPTQQTQHAPQTQQVQQVQQQQTHPRTASQQVDPTFNQQRIQGSFQQIQQQMQMRQHQQHQQQKAQQFTSQIDNWPRPASAKTAEGDPGLMPHSAPETLRATTSGVDFLNSPELLNAKLSPQQGGLSPAKKQAQMRKKMTLKQASNQGTPSAVMPSSTPAPGTGMGPVVSSRTGTPRVANVGLASVSPMATKAVTANQSPSPKSIPNNVGPSGPVSNQYKEDEE
3) KKLQAARNQMGTANASSQQATVPPVSGTGVPQMSQFMPNSGGSQANLAARRPYSGANSNINAFNENPTASELQGPPQNMEQTVLSQPQPQGQVPTQSQTGSQVPGQSQPPPKFSLPRPTEQ
4) KSRLQQVNANNRGPPQGRPNSRVPSAGPGSQAHQGQSALQQPQQPQPHQPQPQMQQPQIVQQSQPQQMPMGQPTQAQTQEVPNVLNRLN
75
622
383
244
231
861
503
332










Molecular Recognition Features






MoRF SequenceStartStop




1) IKFDSPEDLYFSAPAEEVKKEFTKDALAGNAEDSKIWDWSFWD
2) IYIKKYI
3) QMRKKMTLKQA
1032
371
771
1074
377
781