<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10406
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MFSAGISGQEPVSWSKCGLLAYGDRKDIRSNLVITFLETVNGSNWKFHRSRRYAISPHIFEQNTSNSNGTKTGSAAGKTVNCHYPISSLHWNNVGTLAGDMLAVCDQKGNVTFIVAGHGAEGSGTLDRLSVVFQDTVYKMSSQMMPLVEARFGPKLGSKPSKNTGSSLVIHFEWLSGQKPAICMHGAIKDQATGFFKSQVQQCEPWGLFHPASIKSASFAIRRNAQLDFWYQFSNSKEHKKISLQLNNLRQQQTKQLECLRFAKCAHSYEGNSSLVGTYSALENRFSLYKLDINWNSTTTDTTNEPSVALHQIFCFNPDLLGLNGELLELSNFEMISASYDKKSRAELLLCYTIQESSRSLIKRYEVTSFSPATELTAIFGTVTSQTASSGPTNFSLSDMGSLELDGEVVGIETRNFDTVVIFRLKNGYFKIFNRFLWSEEGVTIGDAPKLNDSKKITSITCSGMKYPKVPALEVIDWVHLSPAMGGYAFKMKYQSEASFKAISIPDLSDETENIMHAVSFAHAFVVSNHQQLSGEDLSIAIKEVALKWGQEDNKKGRQFMVEVIRQVMHLFGLTPDTPKELKDKIMMSRPIQRAILLQLELGGSFDNKNMYSLPRAIMLLRNIMFAFNGVSRNIQVIVHHITTMTIQQPASKLFQFAFSKQDLIYSLIPCAKWFVKFITFLTQQLIVLVNNSQMKEETLVLSVLASKISRTLLLSILSEIKKIVQLITKFPETNYPILNESSVYLRKVLGDSQVNFEKFETFLVDVNNKFTSLGEQQNQLSPTNADTYLIFDGDFSEDMKSIKDFLLTYSNMAILSHIKPADVYFADTSALRIFASEYFSPEVFRLLQPIEKGLVIKSNDLPENASSERSFSPLTFDSISHEPINPAKTPKIKRCCRCSAITRTGYPISKENTVIPTSISAKRWSNLYSRVCMCSGFLYELDDD |
Length | 945 |
Position | Tail |
Organism | Lachancea mirantina |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Lachancea.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.167 |
Instability index | 39.26 |
Isoelectric point | 8.46 |
Molecular weight | 106078.26 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP10406
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 107.18| 31| 81| 69| 105| 1
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69- 105 (49.32/45.62) GTKTGSAAGKTVNCHYPIsSLHWnnvgtLAGDMLAVC
153- 183 (57.86/36.80) GPKLGSKPSKNTGSSLVI.HFEW.....LSGQKPAIC
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.63| 16| 81| 321| 336| 2
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321- 336 (27.77/21.80) LGLNGEL..LELSNFEMI
403- 420 (22.86/16.49) LELDGEVvgIETRNFDTV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 63.95| 18| 24| 465| 482| 6
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465- 482 (33.24/20.91) MKYPKVPALEVIDWVHLS
492- 509 (30.72/18.81) MKYQSEASFKAISIPDLS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 65.27| 21| 35| 819| 840| 7
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819- 840 (31.28/21.67) IKPADVYfADTSALRIFASEYF
857- 877 (33.99/18.93) IKSNDLP.ENASSERSFSPLTF
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