<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10392

Description LANO_0C02388g1_1
SequenceMDTDWRSTLSNQERSKYITELAQILAQISQVNGGDRGNFNLEKLKKTAEQFEKSLYASSSSKELYLDSMRKRIAAMDTAKKKAIANLQHNAAKAASLSQSQQHPGSTISSQQMQQQQQQQQQQQQQRPSQFSSSGNNMNSQMFFNQQAQLRQQAAQQFRNGVTPNAPTPSAPSAPNPPVRPQLTPQQQQLINEMKGAEIPRELLQRIPNLPPGVNTWQKVTELAQQKRLGPKDLQIAKQVYQMHQQIVFKSKVQQASVNNRGPQQGRPISQGPNMGQMPSGQRPMVNQANLQQQQQQQQQHHLSQPPQPQQQQQPQQQQQQQQQQQQQQQQQQQQPQPQQQPQQQPQPQPQPQHAQQNQSQQQAPMGQASQQQPQEVPNVLNRLNQIFTPAEQKTLYENGKKLIADLQRTNRLPAVLTPQQQGIYIKKYINQMALKKLQAARSQMSSLNAPAQQQPPVASVQGTSAPPMSHFASNGANMNGAGATMTPRGTFTGNNSNSNNFNDSGGGPNLQGATPTNMPPQASLSQPPVQVQAQAQAQAPAQQAPAQPKFSLPRPTEQDLMVLRRISAEIQKSHLRLSNITNQISQEQKQSIRNKLQLNRQLFTNVDSFIPTLYMITRNEENVRQLLQIRMLAKEITEHATRGVFIVPPEVVDKVIFRYQKYYEFIKDQVLRRHQQIIAARQQQQQQQAPSAPVDPAFNQQRIQGSFQQIQHQMQMRQQQQQQQQQQQQQQQLQQQQQQQLQQQQQQQQQQQQQQQQQQQQQQQKIQPSPQLNNWARLNAEVRPPTTSSVDGEPNLAPQSAPENVRTTSSGMDFLNSPDFFNSKSSPQQAGLSPVKKQTQMRKKMTMKQASNHGTPGAAMVPSSNTPNATTTLGISSTSKTGTPRVATAGLASVSPMVNKVTTSNQSPSPRSFPNNAAPIAASSYSYKEDEDSLKMMVVRKNEIISRFKRRQDILRNSPVDLFLCSLGDCLGISEEKVELMNSIPQDIVEQVNGTSKKKTAKSAAQRSKDQEYANVSIKDNKITFTPNSGLDLQSSNPYSIGVGDISGVFRDVYGSTHLSSFSFESDNSASDARGTKRKAVDSDNSPNASPASSAVMSDSKKIKFDSPEDLCFSAPVESVKKEYSIGGAADNAAENKIWDWSFWDTV
Length1148
PositionTail
OrganismLachancea nothofagi CBS 11611
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.05
Grand average of hydropathy-0.990
Instability index70.86
Isoelectric point9.88
Molecular weight128335.53
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10392
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     193.40|      23|      30|     105|     131|       1
---------------------------------------------------------------------------
  119-  150 (32.83/ 9.60)	QQQQQQQQRPS.QfsssgnnMNSQ.MffnQQAQL
  297-  317 (44.82/11.31)	QQQQHHLSQPP..........QPQQQ...QQPQQ
  331-  348 (36.40/ 7.43)	.QQQQQPQ.PQ.Q........QPQ.....QQPQP
  682-  705 (36.64/ 7.54)	RQQQQQQQAPSaP.......VDPAFN...QQRIQ
  740-  759 (42.71/10.34)	QQLQQQQQQQ...........QQQQQ...QQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     109.33|      32|      32|     382|     413|       2
---------------------------------------------------------------------------
  174-  210 (27.59/ 7.83)	.APNppvrPQLTPQQQQLINEmKGaeipREL...LQ..RIPNL
  215-  243 (27.76/ 7.93)	NTWQ....KVTELAQQKRL....G...pKDLQIAKQvyQM...
  382-  413 (53.98/22.82)	NRLN....QIFTPAEQKTLYE.NG....KKLIADLQ..RTNRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.63|      28|      28|     846|     873|       4
---------------------------------------------------------------------------
  462-  483 (27.56/ 9.24)	QGTSAPPMSHFASNGANMNG.AG......
  841-  868 (44.04/19.58)	QMRKKMTMKQASNHGTPGAAMVP.SSNTP
  869-  897 (35.03/13.92)	NATTTLGISSTSKTGTPRVATAGlASVSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.81|      19|      19|    1067|    1085|       6
---------------------------------------------------------------------------
 1067- 1085 (31.57/20.90)	SDNS..ASDARGTKRKAVDSD
 1087- 1107 (27.25/16.98)	SPNAspASSAVMSDSKKIKFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     157.93|      28|     175|     351|     378|       8
---------------------------------------------------------------------------
  350-  377 (51.89/17.40)	PQPQHA............QQNQSQQQA....PM........GQASQQQPQEV
  527-  553 (39.24/11.09)	.QPPVQ............VQAQAQAQA....PA........QQAPAQPKFSL
  554-  593 (35.23/ 9.08)	PRPTEQdlmvlrrisaeiQKSHLRLSN....IT........NQISQEQKQSI
  769-  806 (31.57/ 7.25)	PSP..Q............LNNWARLNAevrpPTtssvdgepNLAPQSAPENV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.18|      17|     601|      99|     118|       9
---------------------------------------------------------------------------
  100-  118 (28.66/15.29)	SQQHPgsTISSQQMQQQQQ
  280-  296 (31.52/ 7.91)	SGQRP..MVNQANLQQQQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10392 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AMDTAKKKAIANLQHNAAKAASLSQSQQHPGSTISSQQMQQQQQQQQQQQQQRPSQFSSSGNNMNSQMFFNQQAQLRQQAAQQFRNGVTPNAPTPSAPSAPNPPVRPQLTPQQQQLINEMKGAEIPRELLQRIPNLPPGVNTWQKVTELAQQKRLGPKDLQIAKQVY
2) IPQDIVEQVNGTSKKKTAKSAAQRSKDQEY
3) KKLQAARSQMSSLNAPAQQQPPVASVQGTSAPPMSHFASNGANMNGAGATMTPRGTFTGNNSNSNNFNDSGGGPNLQGATPTNMPPQASLSQPPVQVQAQAQAQAPAQQAPAQPKFSLPRPTEQ
4) RQQQQQQQAPSAPVDPAFNQQRIQGSFQQIQHQMQMRQQQQQQQQQQQQQQQLQQQQQQQLQQQQQQQQQQQQQQQQQQQQQQQKIQPSPQLNNWARLNAEVRPPTTSSVDGEPNLAPQSAPENVRTTSSGMDFLNSPDFFNSKSSPQQAGLSPVKKQTQMRKKMTMKQASNHGTPGAAMVPSSNTPNATTTLGISSTSKTGTPRVATAGLASVSPMVNKVTTSNQSPSPRSFPNNAAPIAA
5) VFKSKVQQASVNNRGPQQGRPISQGPNMGQMPSGQRPMVNQANLQQQQQQQQQHHLSQPPQPQQQQQPQQQQQQQQQQQQQQQQQQQQPQPQQQPQQQPQPQPQPQHAQQNQSQQQAPMGQASQQQPQEVPNVLNRLNQIFTPAEQKTLYENGKKLIADLQRTNRLPAVLTPQQQ
75
985
436
682
248
241
1014
559
923
422










Molecular Recognition Features






MoRF SequenceStartStop




1) IYIKKYI
2) KKMTM
424
844
430
848