<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10381

Description LANO_0A01156g1_1
SequenceMPSKYLLTPPESLHSLTTDSRKSIYPDFDPWRHTPIEDKIFLNFVSKGYYNSARVNFESISSRSSLQESLPAVSGLLADQLSQVVCIREDQVNKISAKSQDLKTAHAASTDLCGPGFLLPKRVTLTDHKRELWLQEISSPHSSLAETVKTIPHGLKRRQLLEQCCLKQIPVPRAIWLIKCCYTLEWKTLVNKQSFQERDEASTKLLKEWSDTMAHILEKLVFEMTQFYNEPVKLKNWRQRIAYYLKLLGNCYSLGLIEKDVFHHWLVDFVGKIENFECLPMTLHILTVFWTGIFPKSQEHNSPQQLFQINKMTEALIYKYYMVSTSKSMINDEQYLINDVKKNNKLSMIISSRLKDLIVKIFEEQPMEAFVFPSSNWEIYKNCLYKILQVDGPRDGSKRTTETSKKLELIVYRNDSLKFNTILHEADEDRSVSNNEQFNDLESIFIPKKILKLRHIDYNLTKLLDGNSAGDDWMNFADQKLTRVDQLIQMILWAVHPSRIHHYEASQLVAKLFLLKINIKSGLMEYSLEDKVWALIFVFAKIKTEDLKLVVNLPRLHQLLNVFIGYGLLKVPTYIRKLISSGVLYLPESGDKFFHCDLLINLKISPVMKSQYNMVLRNVIDANPQYYEDFNYDRLMESLEQAKACLSEGKFDFVIRVPYCIKLMASEWYLNHICSTVNGVLTPVTKKDVIEKLKVFCINLEVYHQFYKWVEFIVYHKLLEDLEALECLVDILIYYDKLFSLLINDHILLMKTILHLYSDKLLTDSPESQSLILLSEFWHFFMSKFPLALEIDIDLQTKLLEANEFEKAKIEKVLKQKPGTDEFITNYERHTAHTLQNDNDDAFNFPSIFQPNLKILLTSVVEDEIRCARKMMRVLMIMNLSEYNKFMSIFLKRKTASDEDLARLVSLKILSLTLIQKVLGEYSLVTLLNTVFYEHGMAFELQKRSFTRHNISTVMNAFCDTSPNDYKELLSVLVEYCSFRSAQEHALKIFDSMETRGDNSLHSFAEELLTFGVGESNFAGLQNPLTNKKSAHVINDDGDMTDDEVDVIDLYSRLDFTNLWIFQILTCHYLRQSQGSVESRQSQARFVLDSIRMTNFDLTASKLFDKVTNADVLQQTLQTLEVDFLRGGAEQDSEQNSEQNSQYHTIIETIINISRRLNKVLAGNIPISDESFNLLQTCCREFALKDSNDLSSFEFRLDVFLKILIVHQKFIIREGLQNSRLLLENNGEFLRMLCLLFHKIGFSLKLKLLLYDVLASLKSFVVYSSTGKTSQLSFKGQLKVPQELLDLPPFKITSFMPDSALSSAESSVALGIENMASNKMIEKPTFFIYNKKMERFETKLIVRPFHVLNNFREEGSDFNNTPLNMCLFNACFDRRNPT
Length1378
PositionKinase
OrganismLachancea nothofagi CBS 11611
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.10
Grand average of hydropathy-0.167
Instability index45.58
Isoelectric point6.35
Molecular weight159813.84
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10381
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.28|      15|      26|     206|     220|       1
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  206-  220 (26.94/19.33)	LKEWSDTMAHILEKL
  234-  248 (27.34/19.75)	LKNWRQRIAYYLKLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     754.48|     253|     275|     506|     780|       2
---------------------------------------------------------------------------
  506-  780 (376.04/359.14)	SQLVAKLfLLKINIKSGLMEYSLEDKvwALIFVFAKIKTEDLKLVVNLPR..LHQLLN....VFIGYGLLKvPTyIRKLISSGVLYLPESGDKFFHCDLLINLkispvmkSQYNMVLRNVIDANPQYYEDFNydRLME....SLEQAKACLSEGKFDFVIRVPYCIKLMASEW....YLNHICSTVNGVLTPVTKKDVIEKLKVFcinLEvYHQFYKWVEFIVyhKLLEDLE.....ALECLVDILIYY...DKLFSLLINDhiLLMKTILHLYSDKL.LTDSP....ESQSLILLSEFWHF
  783- 1062 (378.44/286.48)	SKFPLAL.EIDIDLQTKLLEANEFEK..AKIEKVLKQKPGTDEFITNYERhtAHTLQNdnddAFNFPSIFQ.PN.LKILLTSVVEDEIRCARKMMRVLMIMNL.......SEYNKFMSIFLKRKTASDEDLA..RLVSlkilSLTLIQKVLGEYSLVTLLNTVFYEHGMAFELqkrsFTRHNISTVMNAFCDTSPNDYKELLSVL...VE.YCSFRSAQEHAL..KIFDSMEtrgdnSLHSFAEELLTFgvgESNFAGLQNP..LTNKKSAHVINDDGdMTDDEvdviDLYSRLDFTNLWIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.76|      14|      25|     250|     265|       3
---------------------------------------------------------------------------
  250-  265 (22.63/22.35)	NCYSLGLIEKDVFhhW
  277-  290 (28.13/18.35)	ECLPMTLHILTVF..W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.26|      25|      25|     111|     135|       4
---------------------------------------------------------------------------
  111-  135 (45.62/30.84)	DLCGPGFLLPKRVTLTDH..KRELWLQ
  136-  162 (36.64/23.25)	EISSPHSSLAETVKTIPHglKRRQLLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.65|      12|      24|     355|     366|       6
---------------------------------------------------------------------------
  355-  366 (20.44/13.26)	KDLIVKIFE.EQP
  381-  393 (18.21/10.94)	KNCLYKILQvDGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10381 with Med12 domain of Kingdom Fungi
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