<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10378

Description LAMI_0A00914g1_1
SequenceMIPNKCLLSPPEDLHSLTRPNSTQIYPDFSPWTHTQLEDKILISSVSRGYYNSAKVNFESISARSSLQESLSAISEGLADRFTEIVHIREEEINKISGISKRDGKVRFDILCGPGFSLPTRVTLTDHRRELWLQEVSNPHSSLLAVSRTVPQILKRRYVLEQCCTKQIPIFKAVWLIRCSFSMEWKIMMTKHKAQSSDQVCAKLYKEWTGSIVHILERLVFEMTQYSGDASQLKAWKKRSSYFLKLLGNCYTLQLLDRNIFHHWLAELLGKVENFECLPLTLHIASIFWDGICQTTESNSTSEGLFLVSKVTKALLHKYYLISRSRSMLNDEQYLINDVKKNAKIESALLKKMKSMILQIFHEQSMEAFIMPNSNWDLYKPCLYEILNIDKVRNLEGDWGNEHKKLELIVFRNDSLKFDGIPDNSFGTPEPVRNSFEGINGLFVTNFHLKLKKVDCELTDLLDFNSPCDDWLFYAENKLNRIGQIVQMILWAVHPSRRSHYEASYLVAKIMLLKMNSQDSFQEHNIEDIVWALIFRFARIPQDEFQTHVNINKLHQILNILIGYGLIKVPTYIRKIISSGILYLASSEDKFFHCRLLINLKISPLMRSQYNMVLKNVMEYDSTYFEQNNYEELLIMLESAKDSLLSNEYDFVKIVPFSVKFMCSEWYLNLICSPGDDMLPQIEKEDILEKYNIFCDKLKEFNHFYKWVEFITYHQLLTDLESLECLADILMNHERLFSLLINDQILMMKTLIHLYTKSMATQESNFPQLYEFSPLWKFFTKKFQYALDMDPDLHICLTEVCEGEKAAIEQLKKSQDLTIKLYASLRQDSCLLNSDNTHFSFASIFQQNLKSIFNTKDRSSLVLAKRSLRLLFLANPNDYKKFMSVYLKRRNFKLSDLIFLISAKLMSFELINNVLGEQYLTKLLKDGDGAISVSYQLLKTKFINHNFKFVLKLCSGPSTFDFELFDYLVLKHNCSISKRRQISYTFYQLMSNLMEPEREAYLEKSMTGFVHHSNQERPKSLSLAQSGADDRVHDDKENILWLYSLLDFTNKWIFQILSKYLFQKLLVEDEREAKIRTLILEILRISDYNNLCAKLFDDLTDAELVRLLLSAIEGDFLQKCMKSDKISMNYYFIVLEIVTSFSKTFARLHFDSSYFNYENLELFTQCARYFINMSSAELKENEIKLDVYLKLIIVQQQNVFKELVEELNRSESELIERLCALFEKIDFNLKIKLLLYDILSSMRSFMIYASTSRGPQDTKENLLKSKIPDCLLNLPPFKISLFMKRSSELSDSQDLLGLQTFSTSVKMVSDHEYFMFNNETEEFDCPLTLSPFHCLVNYQEDRSADFNNTPLSMSLFGARFDKKNPT
Length1366
PositionKinase
OrganismLachancea mirantina
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.11
Grand average of hydropathy-0.187
Instability index47.65
Isoelectric point6.42
Molecular weight159764.87
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10378
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.09|      12|      22|     518|     529|       1
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  518-  529 (23.27/15.09)	QDSFQEH.NIEDI
  542-  554 (18.82/10.74)	QDEFQTHvNINKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.32|      20|      21|    1311|    1330|       2
---------------------------------------------------------------------------
 1311- 1330 (37.60/20.73)	HEYFMFNNE.TEEF.DCPLTLS
 1333- 1354 (27.72/13.50)	HCLVNYQEDrSADFnNTPLSMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.41|      18|      21|     849|     869|       3
---------------------------------------------------------------------------
  849-  869 (22.91/24.28)	LKsifNTKDRS...SLVLAKRSLR
  873-  893 (26.50/17.27)	LA...NPNDYKkfmSVYLKRRNFK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.63|      13|      21|    1271|    1283|       4
---------------------------------------------------------------------------
 1271- 1283 (24.17/12.30)	LLNLPPFKISLFM
 1295- 1307 (22.47/10.96)	LLGLQTFSTSVKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     164.98|      48|      51|     334|     381|       5
---------------------------------------------------------------------------
  334-  381 (81.80/58.44)	YLINDVKKNAKIESALLKKMKSMILQIFHEQSMEAFIMPNSNWDLYKP
  384-  431 (83.18/59.58)	YEILNIDKVRNLEGDWGNEHKKLELIVFRNDSLKFDGIPDNSFGTPEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     139.93|      34|      51|    1155|    1188|       6
---------------------------------------------------------------------------
 1087- 1131 (35.21/21.24)	.DYNNL......CAKLFDDLTDAELvrlllsaiegdflqkcmKSDKISMNYY
 1155- 1188 (60.71/42.94)	FNYENLELFTQ.CARYFINMSSAEL.................KENEIKLDVY
 1207- 1236 (44.01/28.73)	LNRSESELIERlCA.LFEKI.DFNL.................K...IKLLLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.78|      19|      25|     229|     253|       9
---------------------------------------------------------------------------
  229-  253 (28.65/32.80)	DASQLKAWkkrssyFLKLLG.....NCYTL
  257-  280 (31.13/19.44)	DRNIFHHW......LAELLGkvenfECLPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     199.67|      63|      68|     698|     765|      11
---------------------------------------------------------------------------
  698-  762 (104.47/78.13)	LKEFNHFykWVEFITYHQLLTDLES.LE.CLADILMNHE..............RLFSLLINDQILMMKTLIHLYTKSMATQ
  769-  847 (95.19/57.27)	LYEFSPL..WKFFTKKFQYALDMDPdLHiCLTEVCEGEKaaieqlkksqdltiKLYASLRQDSCLLNSDNTHFSFASIFQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.60|      23|      25|     924|     946|      12
---------------------------------------------------------------------------
  924-  946 (38.48/26.03)	LKDGDGAISVSYQLLKTKFINHN
  951-  973 (35.12/23.01)	LKLCSGPSTFDFELFDYLVLKHN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10378 with Med12 domain of Kingdom Fungi
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