<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10367
Description |
Mediator of RNA polymerase II transcription subunit 8 |
Sequence | MDKPNALGITADEFKAIEQTRQRLFQLSNSIQGLRMDVLKSNPLPPPASLQAQSQILLRNLQSLLETLTENTHVFQHLHVFPDVAYPGRVHENILLQLLRKKLEPGVEEWVERGRETTRELRTSPDGEARLEEVWCDVREWTVERVQKYVLEEAGDVYTEEERHRGVENVRTGLKRGLEEEEDDEESDEEGEGEGDGDEDVVMSGQPQSQQAKPSKPTGPEPEMLFWFEARGDFDLPRNVDLLSQSGMKRGQMGPR |
Length | 256 |
Position | Head |
Organism | Colletotrichum orchidophilum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.871 |
Instability index | 56.76 |
Isoelectric point | 4.69 |
Molecular weight | 29270.21 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364144
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP10367
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 130.31| 31| 34| 190| 220| 2
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160- 191 (40.55/16.78) EE....ErHRGVENVRTGLKRGLEEEEDDEESDEEG
192- 222 (52.84/23.59) EG....E.GDGDEDVVMSGQPQSQQAKPSKPTGPEP
223- 255 (36.93/14.77) EMlfwfE.ARGDFDLPRNVDLLSQSGMKRGQMGP..
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 38.76| 12| 35| 55| 66| 3
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55- 66 (19.51/11.02) QILLRNLQSLLE
93- 104 (19.24/10.80) NILLQLLRKKLE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.00| 11| 34| 1| 11| 4
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1- 11 (20.71/12.18) MD..KPNALGITA
36- 48 (18.29/10.04) MDvlKSNPLPPPA
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