<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10340
Description |
Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MNTEFQTSLSNLENKLNALITSLTTSPTAAGAPAAAVGLLNADDSLTSAIATLRQHQDNYARILRLRAEAASLEDKVKGIVKTVVNYEKEIRTVCNSDEIDSSSDFDSDSSTYDSDAEMQDATDKPRKLRHINEVDYKLLLDFARRISKYNHQAAADAEAGARARVQQGDHDTEMTGTGTNGLEDGEAAPVSSVTKDATSWLDESANMTRQVYMLPYPMEDRIRLGLMGQIQLAAGEGRPGFDPDQEVERLIREAEGFGAADAPPVANVSDEQSRVGEAAKAAAKAGSAAAASSGSGSGGVSAAAPKPKPKATLDLDLDDDDDEDEDDF |
Length | 329 |
Position | Middle |
Organism | Aspergillus bombycis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.576 |
Instability index | 34.84 |
Isoelectric point | 4.43 |
Molecular weight | 35029.86 |
Publications | PubMed=27664179
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP10340
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 32.77| 10| 16| 144| 153| 1
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144- 153 (18.52/10.53) AR.RISKYNHQ
162- 172 (14.26/ 6.91) ARaRVQQGDHD
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|