<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10316

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMSANYWTSSQYNNNLYTKPELNDIRLSLFTKELQKYGNYWLTIPLQFKDQESGSNKQISIYAKELHYDRDYNLRIYLYLQLMKLGKKFQLKQVIISSAMIYLQRFLLKCSIKECNVYYLITTCLYLASKVEECPIHIKSLNLIAKSYWPDFIHSDCTKITEFEFYLIEELESYMIVYHPYDSLKKILQSFTEYVKENLEKENLDNIEDYLLNYEYLQDTWAIINDSYVTDSHLLFHPHVIAITSLLLSIVLKGEQLDQKIEKTTKIIKDIENKKNVEKSNNKAPINNKTVSSDVGSTNNSVNNTTNMHSSETKEFIIPNEEYDEMLMNLGLSGDNNIQNKTLTKDPMSPNINSNSETTELEEGNFQYQGLKEELKQNLIEKELIHKKTAKLNEFVAFSLINMQDIEDCFKEIMILYQFWTGFSVVGQSTKFDKLQKNKYNEEWIRFLLYRVYQTKA
Length456
PositionKinase
OrganismHanseniaspora uvarum (Yeast) (Kloeckera apiculata)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycodaceae> Hanseniaspora.
Aromaticity0.12
Grand average of hydropathy-0.484
Instability index48.22
Isoelectric point5.56
Molecular weight53781.72
Publications
PubMed=27856586

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10316
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.48|      31|      33|      26|      58|       1
---------------------------------------------------------------------------
   27-   57 (56.07/34.39)	SLFTKELQKYGNYWLTIPLQFKDQESGSN...KQ
   59-   92 (49.41/29.15)	SIYAKELHYDRDYNLRIYLYLQLMKLGKKfqlKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.92|      11|      21|     107|     117|       2
---------------------------------------------------------------------------
  107-  117 (20.38/12.62)	LKCSIKECNVY
  126-  136 (19.53/11.82)	LASKVEECPIH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.07|      24|      25|     142|     165|       3
---------------------------------------------------------------------------
  142-  165 (46.31/23.17)	LIA..KSYWPDFIHSDCTK..ITEF.EFY
  166-  193 (31.92/14.24)	LIEelESYMIVYHPYDSLKkiLQSF.TEY
  378-  398 (27.85/11.72)	LIE..K....ELIHKKTAK..LNEFvAFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.31|      23|      50|     285|     307|       4
---------------------------------------------------------------------------
  285-  307 (40.90/24.06)	INNKTVSSDVGSTN.NSVNNTTNM
  337-  360 (37.41/21.48)	IQNKTLTKDPMSPNiNSNSETTEL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10316 with CycC domain of Kingdom Fungi
Unable to open file!