<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10303

Description Uncharacterized protein
SequenceMAIETVPAGNASGSQTEKDMIIPADLQSLQKYLLEQVPQSEPNNKSASASIALNGYMAKVQNEILPLRLEFNALLKQMAHLDNPQESGKQKYLALKARLVTVTTKINDLSQEFKKLQPLLYILKNNQKILETPNSYYILETLDQLPQPEIKVPLPKQFQPKIINTLPNAVSNSTGVNTAVSSAQKATKSPVNSVNSPSTPATAKTPGSVAASNTVKHSLQGNLASASTFSGIRKNAKGSGANAHASSGSVKKPATNSKRGTPQAFSPLSANTPVTNVSASNNSTNLSNIGAVYNSGGRSKNHDQVTSAPLSKANSANESPSMYMNTSNITPANILQNLNSSMGNNSQSSNMGALSSRVGMNGPSGNIGQQRVNNPNSNSNSNNINNNSMNYGNNMNNRVPSTDNSMGGYGYNGNFSMSPSSILQNMNNLPNNNSSVASGNMSPNGSLNTNNNSAGMLDLNTLDLSNLDDFLQ
Length472
PositionTail
OrganismHanseniaspora osmophila
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycodaceae> Hanseniaspora.
Aromaticity0.04
Grand average of hydropathy-0.588
Instability index49.61
Isoelectric point9.61
Molecular weight49891.83
Publications
PubMed=27856586

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10303
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     341.09|      63|      64|     281|     343|       1
---------------------------------------------------------------------------
  169-  226 (58.71/14.15)	.AVSN...S...TGVNtavSS.AQKATKSPVNSVNSPS..TPAT.AKTPGSVAASNTVK..HS.....lQGNLASA
  231-  289 (77.79/21.06)	GIRKN...A...KGSG...ANaHASSGSVKKPATNSKR.GTPQA.FSPLSANTP...VTNV..SASNN.STNLSNI
  290-  351 (106.28/31.38)	GAVYN...S...GGRS...KN.HDQVTSAPLSKANSAN.ESPSM.YMNTSNITPANILQNLNSSMGNN.SQS.SNM
  352-  407 (55.73/13.08)	GALSS...RvgmNGPS...GNiGQQRVNNPNSNSNSNNiNNNSMnYGNNMN....NRVPSTDNSMG..........
  411-  460 (42.58/ 8.31)	...YNgnfS...MSPSsilQN.MNNLPNNN.SSVASGN.MSPNG.SLNTNN.NSAGML.DLN..............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.06|      39|      40|      33|      71|       2
---------------------------------------------------------------------------
   33-   71 (63.97/39.79)	LLEQVPQ.SEPNNKSASASIALNGYMAKVQNEILPLRLEF
   74-  113 (58.09/35.45)	LLKQMAHlDNPQESGKQKYLALKARLVTVTTKINDLSQEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.23|      18|      32|     117|     134|       3
---------------------------------------------------------------------------
  117-  134 (32.36/21.15)	QPLLYILKNNQ...KILET.PN
  147-  168 (23.87/13.66)	QPEIKVPLPKQfqpKIINTlPN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10303 with Med3 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PSSILQNMNNLPNNNSSVASGNMSPNGSLNTNNNSAGMLDLNTLD
2) QGNLASASTFSGIRKNAKGSGANAHASSGSVKKPATNSKRGTPQAFSPLSANTPVTNVSASNNSTNLSNIGAVYNSGGRSKNHDQVTSAPLSKANSANESPSMYMNTSNITPANILQNLNSSMGNNSQSSNMGALSSRVGMNGPSGNIGQQRVNNPNSNSNSNNINNNSMNYGNNMNNRVPSTDNSMGGYGY
3) STGVNTAVSSAQKATKSPVNSVNSPSTPATAKTPGSVAASNTVKH
419
220
173
463
411
217










Molecular Recognition Features






MoRF SequenceStartStop




1) DLQSLQKYLLE
25
35