<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10301

Description Serine/threonine-protein kinase SSN3
SequenceMNGNFNNNANQVPQHITQQQQMLQQSSQTRNAYQDQYSQLQSLQQQQQQQHAHQTSQQQRQVFLMAGNNMFTIGPYKKRKDACRVSVLEKYEIIGYIAAGTYGKVYKAKGKKDALXNQESANKVNLLEISSKNHNADDFASIRNTATKKSIINRSKNNEETTITDIINKKNKLSTPVSDSSSKSADNAXNDAEKKGLKTGSVNGSSGKINLSTSGGNLGPASAELQNQKAHAKPKTQXPQFYAIKKFKTEREGVEQLHYTGISQSACREMALCRELNNKHLTELVEIFLEKKSIYMVFEFAEHDLLQIIHSHSHPEKKLIPPQMLKSIMWQVIDGVSYLHQNWILHRDLKPANIMVTVDGCIKIGDLGLARRYNNLLQTLYTGDKVVVTIWYRAPELLLGARHYTPAIDMWAVGCIFAELIGLRPLFKGEEAKIDSKKTVPFQASQFKKIIEILGTPTTQSWKDIEKFPEYPQVNNRFPHYESNLLNWYQACNGKDKWCFDLLCKLLIYNPIDRIDATAALDHPYFKNNEPPVSENVFEGLSYKYPPRRIHTSDNDIMGIGKVAQQQQQQQLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQHLESQAQGVFDNQVQQPQVNQTNNTFSNNLQEATLIDPNISSRASYSAPLKMRATGTAQDLTDTQVQHKQNQASSNVQSTSFHQPAPNDLYRPLGVQTASGSTKKSTDLSAQASAAAILKQQQQLQYLQQQGKNLTPQQLQRLKQMHAKKTKQNSFDKGINERIMAAAATAAAAVSKPGDTANKKRKK
Length815
PositionKinase
OrganismHanseniaspora osmophila
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycodaceae> Hanseniaspora.
Aromaticity0.07
Grand average of hydropathy-0.869
Instability index55.59
Isoelectric point9.44
Molecular weight92188.53
Publications
PubMed=27856586

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10301
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.48|      15|      15|     575|     589|       1
---------------------------------------------------------------------------
  574-  588 (33.95/ 9.22)	LQQQQQQQQQQQQQQ
  589-  600 (27.88/ 6.44)	QQQ...QQQQQQQQQ
  601-  615 (34.65/ 9.53)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.67|      36|      50|     625|     665|       2
---------------------------------------------------------------------------
  633-  684 (42.53/26.76)	AQGVFDNQVQQPQvNQTnntfSNNLQEATLIDPnissrasysapLKMRATGT
  685-  724 (57.15/23.73)	AQDLTDTQVQHKQ.NQA....SSNVQSTSFHQP.......apndLYRPLGVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.44|      20|      30|     354|     373|       5
---------------------------------------------------------------------------
  354-  369 (22.52/13.10)	........IMVTVDGCIKI........GDLGL
  370-  399 (19.05/10.06)	ARRY..nnLLQTLYTGDKVvvtiwyraPELLL
  401-  423 (29.87/19.51)	ARHYtpaiDMWAV.GCIFA........ELIGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.73|      20|      23|     131|     152|       7
---------------------------------------------------------------------------
  131-  150 (33.43/22.16)	SKNHNADDFASIRNTATKKS
  155-  174 (32.30/15.03)	SKNNEETTITDIINKKNKLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.06|      22|      23|     305|     326|       8
---------------------------------------------------------------------------
  305-  326 (39.84/26.51)	LLQIIHSHSHPEKKLIPPQMLK
  329-  350 (40.22/26.84)	MWQVIDGVSYLHQNWILHRDLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.67|      15|      15|     739|     753|       9
---------------------------------------------------------------------------
  739-  753 (23.33/ 8.50)	QASAAAILKQQ.QQLQ
  756-  771 (22.34/ 7.82)	QQQGKNLTPQQlQRLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10301 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KINLSTSGGNLGPASAELQNQKAHAKPKTQ
2) MNGNFNNNANQVPQHITQQQQMLQQSSQTRN
3) NADDFASIRNTATKKSIINRSKNNEETTITDIINKKNKLSTPVSDSSSKSADNAXNDAEKKGLKTGSVNGSS
4) QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQHLESQAQGVFDNQVQQPQVNQTNNTFSNNLQEATLIDPNISSRASYSAPLKMRATGTAQDLTDTQVQHKQNQASSNVQSTSFHQPAPNDLYRPLGVQTASGSTKKSTDLSAQASA
5) QYLQQQGKNLTPQQLQRLKQMHAKKTKQNSFDKGINER
208
1
135
583
753
237
31
206
742
790










Molecular Recognition Features






MoRF SequenceStartStop




NANANA