<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10292

Description ATP-dependent RNA helicase DBP6
SequenceMFAARFVPGAIESKVSKKNTEKSAPKKVLPLKRSREITEKDHEEEESMDDESSDEDSSEDSXKDSSEDSSEDSSEDSSEESTTDDSNEDKQGKEGLSEQISTIKDKTEIVLNEQNTNDDTDKSSTLTETKEYSDSKHSSVLSRFKQTLTIQDELQKKNKNKGLEGAXLEEYNDQQGAQEDADVVLHDLAPIPQPAKIYSNAHDSATSLKLDTSTAWSHTTKIIYNNGMIKSWEDLPLSKLLVKNVKHNFKSEKAFPIQTSLITTVLPLLQFNYNINKRMYPQRTGDILVNASTGSGKTLAYALPIIEILKKRTINRTRCVVIVPTKMLIHQVFETFNKLTQGTSLVLTTTKLEMSLKEEITKFEKQQPDILIITPGRLVDHINSGSISLQDLKFLVLDEADRLLNQSFQNWCDLVMNELKKHDKLNNVIKMVFSATLTTNTEKLHHLHLNTTNTKLFIMDSIKLYHIPSSLQEHNIKISSSKSVYKPLYLTKVLKNLNSISNSLEKAFKVLVFVKSNESSIRLSPLIQALWKENESQISSINSNNSKQENKVVLERFSKTQTFNLHAGISVLISTDIMSRGIDINDITHVVNYDVPISSQQYVHRSGRTARALRSGDVYNLLVGRGEYNFWKNQIDIDLSRDVGGCEVVEEDTTGNSDAALEENHYLSLNELEVAEYKKCLQSFSSX
Length687
PositionKinase
OrganismHanseniaspora osmophila
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycodaceae> Hanseniaspora.
Aromaticity0.06
Grand average of hydropathy-0.581
Instability index48.64
Isoelectric point5.63
Molecular weight77197.83
Publications
PubMed=27856586

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
helicase activity	GO:0004386	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10292
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.36|      23|      23|      81|     103|       5
---------------------------------------------------------------------------
   81-  103 (36.28/22.96)	STTDDSNEDK...QGKEGLSEQISTI
  115-  140 (30.08/17.64)	NTNDDTDKSStltETKEYSDSKHSSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.19|      23|      24|     325|     348|       6
---------------------------------------------------------------------------
  324-  347 (33.60/25.78)	PT...KMLIHQVFETFNKlTQGTSLVL
  348-  373 (32.59/20.05)	TTtklEMSLKEEITKFEK.QQPDILII
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.78|      12|      15|     510|     521|       7
---------------------------------------------------------------------------
  510-  521 (19.23/10.88)	VLVFVKSNESSI
  527-  538 (21.56/13.04)	IQALWKENESQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.44|      12|      24|     391|     405|       8
---------------------------------------------------------------------------
  391-  405 (15.62/19.07)	DLkflVLDE...ADRLLN
  413-  427 (17.82/10.49)	DL...VMNElkkHDKLNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10292 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MFAARFVPGAIESKVSKKNTEKSAPKKVLPLKRSREITEKDHEEEESMDDESSDEDSSEDSXKDSSEDSSEDSSEDSSEESTTDDSNEDKQGKEGLSEQISTIKDKTEIVLNEQNTNDDTDKSSTLTETKEYSDSKHS
2) TLTIQDELQKKNKNKGLEGAXLEEYNDQQGAQEDADVVLH
1
147
138
186










Molecular Recognition Features






MoRF SequenceStartStop




1) EFQTIRDYIKFLDL
223
236