<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10281

Description Uncharacterized protein
SequenceMNINQQSAQRWQATLSATDRQKFIAILKQAYFQTPNPPDDVHQIAQDFESYSYQNARSKEMYASLCKHKLLEIKSGAAAAVAAAAANNSGSGNGGNIHNMIPQQLLNGAAAAGGSGATSNSNNNNNNNNNNNINNSGINNSASNISNNIANNNSNGANGQLPNLNPEQTRAFLARQAQVRQQAAQSLLQQHQQQQQQTGNSNNNNTNNNSNNNNNNNNNGNNKGNQAGGTGPQHSPAMPMAPMNPMNSTKPLAAIDLRSTPIPDALLSKIPGLPAGVHTWGQIMDLATKQVFSPEVLNTIKNVHQMHQQLLLLRQEQTLKQGVGAINANPNNKPNNNTNNFTFNTNATAAMMNQQRAALAKQAQQAAQQQMQLRAQQAQQAQQQAAAAAAAQIPGANNRFNQAQQQQQQQQQALNSNSNNQQRLPLTQSIPQQVLKDGTTQALQLLQRLQAQGAVPRDLTQEQKQAFIKKFIIHQIEQLKKNAANNNANNNNSSNNGNNNNNNNNNNNNNNNNSNNTNNNNMPLPLSANQAQVQARMQQTAAAAASNNITAPPQQQQMGGYVPPLPPHARWNGNNGIVPQQGNNNNQSNNNNNNASLQQKLALQAQNSHLPTMQHQRLQHQQQGLPTNDQHIRPNNLNPQSAQFSQIAQQAAQQQQAQQAQQQNPRGTIIATEEDKQELKKLVEDSSKFAINLRNLTNEMSPDEKKYILSQFKTLVSMLSMTDNIIPNFYFITKNKDGTSKLLSMRIMIKIIINGLKNNEFYANQLLYTKIQTQIQRYVNYIKEYQKTYASKISGINTNIPQVRNNWQQQAAQQAQQQAQAAQQRLNQQQLYQNMQGGLPQNKAMLHQQAQAQAAQQQQQQQQHQMMPSHVPHNLQPTVDSNNPLSQQAQLFQNMPAQDAALLSMTMPGTTPAQQFQAAPTGLPPSAPLTPQLIQQQAAQRFAPSMANNSMRSSPIVPAPILPNPIQQQQQLHPAQHQYQQAQQQQQQQQAQPQQKVSNTTTPTGTSVGLTSKKLTPNRRKSKTVQKANKTQQPPKVEVSSVATSNNNSSGSLTSSEKPGSNVSKMATPSSLSMSPANQAFLKEQAEKLAREEALRSEEEASRIQRQQLAAIDPTLYFLSSLSHAFGLKEEESKLVHSKNSPTFNKQMSPSMVKGITPSAILQTPTPFNVRTPASGRRSSPVTNKYNSKATNEAIIDEENNWKCTLKPAAVRSAFKEVPSIERTIFNLMIPTPPEENLTDGILKNENENENENNIKIQINDKKRKFEGDNDMGPLNKESKIGFFKESEAIDPIWDFNSISAP
Length1302
PositionTail
OrganismPachysolen tannophilus NRRL Y-2460
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Pachysolen.
Aromaticity0.04
Grand average of hydropathy-0.928
Instability index53.39
Isoelectric point9.84
Molecular weight143418.30
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10281
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     260.93|      38|      84|     103|     140|       1
---------------------------------------------------------------------------
   98-  129 (44.72/ 8.20)	HNMI...........pQQLLNGAAAAG.GSGATSNS.NNNNN..NNN
  519-  558 (40.22/ 6.59)	NNNMPlPLSAN.QaqvQARMQQTAAA....AASNNItAPPQQ..QQM
  559-  595 (47.69/ 9.26)	GGYVP.PLPP......HARWNGNNGIVpQQGNNNNQ.SNNNN..NNA
  797-  835 (44.87/ 8.26)	NTNIP.QVRNNwQ...QQAAQQAQQ.Q.AQAAQQRL..NQQQlyQNM
  836-  863 (43.62/ 7.81)	QGGLP.....Q.N...KAMLHQQAQA...QAAQQ.Q....QQ..QQQ
  969-  999 (39.81/ 6.44)	QQ....QLHPA.Q...HQY..QQAQQQ.QQQQQAQP.QQKVS..N..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     470.12|      74|     284|     157|     230|       2
---------------------------------------------------------------------------
  130-  202 (90.85/26.99)	..........NNNINNSGiNNSASNISNNiannnsngANGQLP..NLNPEQTRAFLA....RQA............................................QVRQQA..AQSL.............LQQHQQQQQQTG..N..SN
  203-  329 (77.62/21.70)	NNNTNNNSNNNNNNNNNG.NNKGNQAGGT.....gpqHSPAMPmaPMNPMNSTKPLAaidlRSTpipdallskipglpagvhtwgqimdlatkqvfspevlntiknvhQMHQQL..L..L.............LRQEQTLKQGVGaiN..AN
  331-  417 (88.80/26.17)	NNKPNNNTNNFTFNTNAT.AAMMNQQRAAlakqaqqaAQQQM........QLRAQQA....QQA............................................Q..QQA..AAAAaaqipgannrfnqAQQQQQQQQQAL..N..SN
  418-  489 (66.83/17.39)	SNNQQRLPLTQSIPQQVL.KDGTTQALQL...lqrlqAQGAVP.rDLTQEQKQAFI............................................................KKFI.............IHQIEQLKKNAA..NnnAN
  629-  664 (61.30/15.18)	DQHIRPNN......................................LNP.QSAQF........S............................................QIAQQA..AQQ...............QQAQQAQQQ........N
  883-  948 (84.73/24.55)	NPLSQQAQLFQ.........NMPAQDAAL........LSMTMP..GTTPAQ..QFQA....APT............................................GLPPSAplTPQL.............IQQ.QAAQRFAP..S.mAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.61|      12|      18|     490|     501|       3
---------------------------------------------------------------------------
  490-  501 (24.30/ 9.21)	NNNSSNNGNNNN
  507-  518 (24.32/ 9.23)	NNNNNNNSNNTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.90|      34|      43|    1056|    1089|       4
---------------------------------------------------------------------------
 1036- 1059 (19.86/ 6.17)	KVEVSS..VAT..SnnnSSGSLT...................................................sSEKP
 1060- 1100 (48.44/25.04)	GSNVSK..MAT..P...SSLSMSP.........................ANQAF.LKEQAE.KL....areealrSEEE
 1101- 1150 (28.09/11.61)	ASRIQRqqLAAidP...TLYFLSS.........................LSHAFgLKEEES.KLvhsknsptfnkQMSP
 1151- 1208 (26.51/10.57)	..SMVK..GIT..P...SAILQTPtpfnvrtpasgrrsspvtnkynskaTNEAI.IDEENNwKC...........TLKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10281 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAANNSGSGNGGNIHNMIPQQLLNGAAAAGGSGATSNSNNNNNNNNNNNINNSGINNSASNISNNIANNNSNGANGQLPNLNPEQTRAFLARQAQVRQQAAQSLLQQHQQQQQQTGNSNNNNTNNNSNNNNNNNNNGNNKGNQAGGTGPQHSPAMPMAPMNPMNSTKPLAAIDLRSTP
2) EEESKLVHSKNSPTFNKQMSPSMVKGITPSAILQTPTPFNVRTPASGRRSSPVTNKYNSKATNEA
3) HQIEQLKKNAANNNANNNNSSNNGNNNNNNNNNNNNNNNNSNNTNNNNMPLPLSANQAQVQARMQQTAAAAASNNITAPPQQQQMGGYVPPLPPHARWNGNNGIVPQQGNNNNQSNNNNNNASLQQKLALQAQNSHLPTMQHQRLQHQQQGLPTNDQHIRPNNLNPQSAQFSQIAQQAAQQQQAQQAQQQNPRGTIIATEEDKQ
4) LKQGVGAINANPNNKPNNNTNNFTFNTNATAAMMNQQRAALAKQAQQAAQQQMQLRAQQAQQA
5) PEENLTDGILKNENENENENNIKIQINDKKRKFEGDNDM
6) QGGLPQNKAMLHQQAQAQAAQQQQQQQQHQMMPSHVPHNLQPTVDSNNPLSQQAQLFQNMPAQDAALLSMTMPGTTPAQQFQAAPTGLPPSAPLTPQLIQQQAAQRFAPSMANNSMRSSPIVPAPILPNPIQQQQQLHPAQHQYQQAQQQQQQQQAQPQQKVSNTTTPTGTSVGLTSKKLTPNRRKSKTVQKANKTQQPPKVEVSSVATSNNNSSGSLTSSEKPGSNVSKMATPSSLSMSPANQAFLKEQAEKLAREEALRSEEEASRIQRQ
7) QQAAAAAAAQIPGANNRFNQAQQQQQQQQQALNSNSNNQQRLPLTQSIPQQVLKDGTTQAL
84
1130
474
319
1234
836
383
261
1194
677
381
1272
1107
443










Molecular Recognition Features






MoRF SequenceStartStop




1) ESKIGFFKESEAIDPIWDFNSISA
2) FIAILKQAYF
1278
23
1301
32