<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10276

Description Uncharacterized protein
SequenceMNKNHKGTGNATETSPIKRYVLEKPKDVFPLNGDEPFSNSNSSNNPPSSFHNAGKKHYVYPDFNPWSYNPQQDVVMQNHLQKGYYSAPVVNNELLSAKNMVHQLLNTDNMNNSSAGTTVTSNSDSDQIVNKTTSTNSKLNALSENIIEAMNLRQEYNRVHVKSAYKPPPRVTLTDHKKELWLQNLANPDDPLSRLSRTIPHGIRNKLLLDQCCSKKIPIPRAIWFVKCVGTNELRGLRRKNAPGSIVATGGNNAKISENNWIHDWTIQVTEYMEKIARDCFTYKEKETAPTSNIENSWKDNLNYIIKLTAHLYLEELINQEVFLNWIVKFLKKIYNDEKSENSYEYSTGDFKLISFHIIIIKLFWFQLIKVDYLSNELSEFMLLNYLKLLEDTTLTKSIRKSLLSNLKFLIFYLFYYNSSSFIIPNNWLLLKPVLQKIIDLNNPIISAQFEIISYRNESLMIDFPDNNLNPASSVSIIKKLDSFNGSNINELSKLIFEITNKTLDDNNESTPDNTSNDWKLHLKLLLNWCVSSYRKNDDTQRVYLTVSIVRYYLWSLSSRPALAKSAIKTKKLEIEIEILEFIYAINDKFSKSLVGTHEQELPVNIDNFLILVNKLYVSKLFTVSSYLRRLISSGIIYLPKALDNCMVHLLIIQNLPILNNTQCNTILKTLTNEEVGSSMDMDMEFQKSKKIISIFLDYMIDNDDLLNFDNDYNWEFLNSLNLGLKFLTADHLFNELRTRINNSQKLVTVTKEKIAVCYKLFEILNNNSKFFQEFLSYVLVNENRMINLYLETLYFITEIVSSNYTLVNSLTPLVWDGNGSTASTVFTRILVMVISNYNFLKSNDSFNFIDFWKFSIEVTKENNLLNDLNNLVIYETTNRENELGKEDLLEILRDFKIENLNPDEFLDQYHFKDNVVMLLHNFLDQIRLESINGEYLSQSLESIIKLLQVLKNSNRTSLDTILMEYINNDILPSLYLDFDAYLKFIMKLLIHEFMSLMQVIQIFGKEETIADNITGNSNHKLIWYLLLREDINCHLTHYESLKFKLIKQNFELTHPSYILKYIVKGILEAQSNTNITAVSPDSTAAVVMETQMGNVMDHLPTPVSNNNATPLPLISGATPMIIDSVHFKNTFLSAFHKKISKVFNKLLFTNAPLLIEQVVSNDFINEDEMLEIFNELLLLDSKAIFNSKDLYRVMEVLNNFNLPICQVALKIIFENEFGSDKSDDFKLISIQDILMMLFSNSRQMEEKRIQNDNNNCRLLSQLFDLLSPDLKLLVLNAAESYFLRSENFPKVYLPSSENESLVPYLIDIINNCSKTSNNCEHKALPLTDSLIFSLNLSLEKLIDSCDKVINVSDSNYQSSLSENIIERNSTVMGKEHEELCTSISLFLKIILIHKTFLVDLILKRSVDLSTDTFLQNLVKLYSSTIVSHNSKLKNLLYDILLSLEILFTEAISVNMESFKAQEEASTANGASNESSARANTGSIMQLPPLNTKNKLSIFLKDLKLRDGLIDLNNTQKLYLYNEKAELYQKFKSKPFDLIEDSNPIIGMNNSSVSLQLFNALIEKKNPG
Length1568
PositionKinase
OrganismPachysolen tannophilus NRRL Y-2460
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Pachysolen.
Aromaticity0.10
Grand average of hydropathy-0.199
Instability index31.92
Isoelectric point5.70
Molecular weight180476.77
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10276
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     253.46|      75|      91|     471|     545|       1
---------------------------------------------------------------------------
  471-  501 (29.39/ 9.31)	...............................................................PASSVSII..KKLDSFNGSNINELSKLIFEITN
  502-  588 (103.07/49.71)	KTLDDNNE.STPDNTSNDWKLHLKLLLN..WCVSSY.RKNDDTQRVYLtvsivryylwslssrPALAKSAIktKKLEI....EI.EILEFIYAIND
  592-  673 (93.14/44.27)	KSLVGTHEqELPVNIDNFLILVNKLYVSklFTVSSYlRRLISSGIIYL.........pkaldnCMVHLLII..QNLPILNNTQCNTILK...TLTN
  674-  705 (27.85/ 8.46)	EEVGSSMD.M..DMEFQKSKKIISIFLD..YMID.....NDD......................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.75|      28|      29|    1130|    1157|       2
---------------------------------------------------------------------------
 1130- 1157 (44.90/23.81)	NTFLSAFHKKISKVFNKLLFTNAPLLIE
 1162- 1187 (38.52/19.36)	NDFIN..EDEMLEIFNELLLLDSKAIFN
 1195- 1216 (28.33/12.24)	MEVLNNFNLPICQVALKIIFEN......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     195.59|      54|      55|     884|     937|       3
---------------------------------------------------------------------------
  265-  316 (78.98/50.29)	WTIQVteYMEKIARDCF....TYKEK..ETAPTSNIENSWKDNL..NYIIKLTAH................LYLEE
  884-  922 (53.83/31.46)	.....................LGKEDLLEILRDFKIENLNPDEFLDQYHFKDNVV................MLLHN
  923-  993 (62.78/38.16)	FLDQI..RLESINGEYLsqslESIIKLLQVLKNSNRTSL..DTILMEY.INNDILpslyldfdaylkfimkLLIHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.73|      37|      54|    1308|    1344|       4
---------------------------------------------------------------------------
 1308- 1344 (64.86/34.27)	D.IINNC....SKT..SNNCEHKALPLTDSLI.........FSLNLSLEKLID
 1364- 1408 (49.06/24.18)	N.IIERN....S.T..VMGKEHEELCTSISLFlkiilihktFLVDLILKRSVD
 1412- 1446 (21.80/ 6.76)	DtFLQNLvklySSTivSHNSKLKNL.LYDILL..........SLEI.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.64|      12|      49|     353|     367|       5
---------------------------------------------------------------------------
  353-  364 (21.16/10.88)	LISFHIIIIKLF
 1228- 1239 (21.48/11.76)	LISIQDILMMLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.65|      59|     606|     381|     453|       6
---------------------------------------------------------------------------
  381-  446 (91.53/63.11)	FMLLNYLKLL........EDTTLTKsIRKSLLSNlkflifYLFYYNSSSFIIPNNWLLLKPVLQK...IIDLNNPII
  805-  874 (89.12/38.36)	YTLVNSLTPLvwdgngstASTVFTR.ILVMVISN......YNFLKSNDSFNFIDFWKFSIEVTKEnnlLNDLNNLVI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10276 with Med12 domain of Kingdom Fungi
Unable to open file!