<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10254

Description Uncharacterized protein
SequenceMNGGNQQQNFIPNHQGRQMPPNQQQQQQQQQQQAASNQITAQDRIQFVNIIVSSIAKIQGSNFSIQKTKPVTEEYEKVAFQNSSSKKEYVEYLRSKITSITQARQNAMQRQQQQAQAQGQANVQQIPQHPQHQQQQQQQQIPQQYANIPNQTQQHQQFNMAQPQQQPQQPQQQQQQQMRPQSTNQMYGLQQQQQQQHQHQQQQQQQPEAHLPQQQNMKPQPQPQSQPQAQQQRAASAPGLKIDLQNLQIPPALLSKLPQVFPRGFNTWATIMPFFRQKQMTPQNMETIKEVYTMHLQLVRAKQQQDMNINKSGAPTMQSNTTAANNNNNNKPNPQFTQQVPQQKPVANQPIMQGGSNNQAPNPQQILLQQQRQQKIKQMQQQQQQQQQQQQQQQQQQQPPQQPQQQNGPPLFNQQQQSHIPNQEIPNMMRPQHHMQGIQQQQLPVQQQKPVPQQPQHSGQQQQQQQQPPQQNSGMRAPFTTEQMQAYKAQALKVIKNLQASNKLPATLTQEQENNYVRKYLFHLLNNAKQQQQQQQPQPQLQQPPQQQQQRQVQPPVQQPQQPQMGSNHTAPAPVIPQQQQQQQQQPLPQALNQQRPQPSPVLTQQQLAQLQQQQQQMQQQNMSNQSPEMMHAQLKMMQAQLHQQQQQQQRGIQGNNIQPTPQQQQQRNIPPQFNPQQQQQPPAATPVYQMLPAQPVQQQQQQQAVPPPQLLPTNQNQRLPQNRQQFARPPNQQQMNQPPQSAVTAAAGPKLFTGVQATDEDWKKLKAICQEVISTPINLKDFTDELSEDEKQQIIKMIRNSQQLILISETIIIPNFYMMTKNYDGTKKLMYSQLMIKQVLERLKNAGRFYANYELLTKVQNQITRFLGYIKEQNAKMMKAQKLPIPIQQQQQQQQQQQLQQQQQLQQQHQQPQLQPQQGRFGQPGGVPMMAQAGQPGTISPQQQFVNQQPQNTSNMQSVSQQFQQLAEQRLVPQATPTPQQLSAMNAGKMPAQFVAPNNNLSPVTATPQIAAVPLPQQGVPGAAPAKKTPTRRKSTKGPTPLQTSQAITPKSKTTPQMQHAATATATAGMVVATPQSQPSSAPAMSPEAQSILRENSALIAKEELKLKNIDNHRNRRRELCQYDPAKYLLATLADSLNLVEEEAKILDSKHQSSTPSSSSNNAKDQASSVNKSHNQTGSLTNANHSVLTPSAILTTPLAFNVKTPNSSRSFNSLMTPSGGTHSLNLSGNPQFNTMADSAKVKATVVADAFKGIVSMLPIPWKFQPNDISSSSAGNHTSMGSGSDTSVGFKSGSVFGELTGLIYPTPPDELIINNATVSTSDSEFGASGKRKFAQSVGTEETENPINRKKIKAEGDIEGFYGLSSDTDKMWNFDNW
Length1376
PositionTail
Organism[Candida] arabinofermentans NRRL YB-2248
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Pichiaceae> Ogataea> Ogataea/Candida clade.
Aromaticity0.04
Grand average of hydropathy-1.085
Instability index76.42
Isoelectric point9.92
Molecular weight155276.99
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10254
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|    1324.91|     189|     190|     369|     557|       1
---------------------------------------------------------------------------
    6-  180 (184.26/21.22)	..QQQNFIpnhqgRQ........MPP.NQQQQQQQQQQQAASNQITA.Q.D..R.....IQFVNIIVSsiaK.IQG.............................SNfsiqktkpvteeyekvafqnssskkeyveylrskitsI.TQARQNAMQRQQQ..QAQA..Q..GQA.NVQQ...IPQ....H.PQH..QQQ......QQQQQ.......IPQQYA...............................NIPNQTQQHQQ........F...N.MAQP....QQQPQQP...Q.................QQQQQQ.MRP..
  181-  368 (228.41/28.78)	.....QST.....NQ........MYGlQQQQQQQHQHQQQQQQQPEA.HlP..Q.....QQNMKP..Q...P.QPQ.............................SQ.....................................P.QAQQQRAASAPGL..KID.LQN..LQI.PPALLSKLPQ....VfPRGFNTWAtimpffRQKQM.......TPQNMETIKEVYTMHlQLvRAKQQQDMNINKS.GAPTMQSNTTAANNNNNNKPNPQF.......TQ....QVPQQKPvanQPIMQggsnnQA....PNPQ......QILL
  369-  557 (364.93/52.17)	QQQRQQKI.....KQ........MQQ.QQQQQQQQQQQQQQQQQPPQ.Q.P..Q.....QQNGPPLFN...Q.QQQ.............................SH.....................................I.PNQEIPNMMRPQH..HMQGIQQ..QQL.PVQQQKPVPQ....Q.PQHSGQQQ......QQQQQ.......PPQQNSGMRAPFTTE.QM.QAYKAQALKVIKNLQASNKLPATLTQEQENNYVRKYLFHLLN.NAKQ....QQQQQQP...QPQLQ.....QP....PQQQQQRQ.VQPPV
  558-  710 (185.13/21.37)	QQPQQPQM.....GSnhtapapvIPQ.QQQQQQQQPLPQALNQQRPQpS.PvlT.....QQQLAQLQQ...Q.QQQ..........................mqqQN.....................................M.SNQS.PEMMHAQL..KMMQAQL..HQQ.QQQQQRGIQG.nniQ.P..TPQQQ......QQRNI.......PPQ..........................................................fNP......QQQQQPP.aaTPVYQ.mlpaQP....VQQQQQQQaVPPPQ
  713-  888 (151.51/15.61)	PTNQNQRL.................P.QNRQQFARPPNQQQMNQPPQ.S.A.vT.....AAAGPKLFT...G.VQAtdedwkklkaicqevistpinlkdftdelSE.....................................D.EKQQIIKMIR..........NS..QQLiLISETIIIPNfymmT.KNYDGTKK......LMYSQlmikqvlERLKNAG.RF.......Y.ANY.....ELLTKVQ..NQITRFLG......YIKE......Q.NAKM....MKAQKLP..............................IPI
  889- 1060 (210.66/25.74)	QQ..QQQ.................QQ.QQQQLQQQQQLQQQHQQPQL.Q.P..QqgrfgQPGGVPMMA...QaGQP.............................GT.....................................IsPQQQFVN.QQPQNtsNMQSVSQqfQQL.A..EQRLVPQ....A.TP........................TPQQLSAMNAG.........KMPAQFVAPNNNLS.....PVTATPQIAAVPLPQQGVPGAA.PAKKtptrRKSTKGP...TP.LQ.....TSqaitPKSKTTPQ.MQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.07|      40|      45|    1229|    1269|       2
---------------------------------------------------------------------------
 1229- 1264 (56.54/32.20)	.....................GNPQF.........NTMAD....SAKVKATVVADAFKGIVSMLPIPWKF
 1266- 1307 (38.63/21.07)	PNDI............ssssaGN..H.........TSMGSgsdtSVGFKSGSVFGELTGLI..YPTP...
 1308- 1373 (48.90/24.04)	PDELiinnatvstsdsefgasGKRKFaqsvgteetENPIN....RKKIKAEGDIEGFYGLSSDTDKMWNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.31|      25|      36|    1152|    1187|       3
---------------------------------------------------------------------------
 1152- 1176 (43.42/35.03)	HQSSTPSSS.SNNAKDQASSVNKSHN
 1201- 1226 (40.89/14.35)	FNVKTPNSSrSFNSLMTPSGGTHSLN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10254 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQKLPIPIQQQQQQQQQQQLQQQQQLQQQHQQPQLQPQQGRFGQPGGVPMMAQAGQPGTISPQQQFVNQQPQNTSNMQSVSQQFQQLAEQRLVPQATPTPQQLSAMNAGKMPAQFVAPNNNLSPVTATPQIAAVPLPQQGVPGAAPAKKTPTRRKSTKGPTPLQTSQAITPKSKTTPQMQHAATATATAGMVVATPQSQPSSAPAMSPEAQSILRENSA
2) EEEAKILDSKHQSSTPSSSSNNAKDQASSVNKSHNQTGSLTNANHS
3) FNTWATIMPFFRQKQMTPQNMETIKEVYTMHLQLVRAKQQQDMNINKSGAPTMQSNTTAANNNNNNKPNPQFTQQVPQQKPVANQPIMQGGSNNQAPNPQQILLQQQRQQKIKQMQQQQQQQQQQQQQQQQQQQPPQQPQQQNGPPLFNQQQQSHIPNQEIPNMMRPQHHMQGIQQQQLPVQQQKPVPQQPQHSGQQQQQQQQPPQQNSGMRAPFTTEQMQAYKAQALKVIKNLQASNKLPATLTQEQENNYVRKYLFHLLNNAKQQQQQQQPQPQLQQPPQQQQQRQVQPPVQQPQQPQMGSNHTAPAPVIPQQQQQQQQQPLPQALNQQRPQPSPVLTQQQLAQLQQQQQQMQQQNMSNQSPEMMHAQLKMMQAQLHQQQQQQQRGIQGNNIQPTPQQQQQRNIPPQFNPQQQQQPPAATPVYQMLPAQPVQQQQQQQAVPPPQLLPTNQNQRLPQNRQQFARPPNQQQMNQPPQSAVTAAAGPK
4) MNGGNQQQNFIPNHQGRQMPPNQQQQQQQQQQQAASNQI
5) YVEYLRSKITSITQARQNAMQRQQQQAQAQGQANVQQIPQHPQHQQQQQQQQIPQQYANIPNQTQQHQQFNMAQPQQQPQQPQQQQQQQMRPQSTNQMYGLQQQQQQQHQHQQQQQQQPEAHLPQQQNMKPQPQPQSQPQAQQQRAASAPGLKIDLQNLQI
881
1142
265
1
89
1099
1187
751
39
249










Molecular Recognition Features






MoRF SequenceStartStop




1) NFIPNHQG
9
16