<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10245

Description Uncharacterized protein
SequenceMNNQKVVALPGQIPRPEGVYPLNGEDPNSAGLGGSGSVGTGNSLNSSKGLNGSGNYTYQSNMLLNHTNVEPIYPDFKVWKHTSKDDALMRSHLQKGFFETSCVSNESHSGRQIVTQLLNRPSSSSTNGNSLNGGTPANEAVENTIKTKLNNLSEVMVKTILRRRELNKIKTKSTYKPPPRVTLTDHKREMWLKNLADPNIPLKQLSRAVPHGLRNRVLLEQCVNHKIPIHRAIWLIRCVSTNEQRQLKRKLQSSTASQSVTVGKWIVEWTEQVTLFIEQIISNCFVPANRSTWRYKLNYFIELSGNLYLQNLMNRETFLSWIVHYAGRLIHKDCTDLQGFKTLSVHYLFIKLFWFKIINVDYLSKELNENMLLAIAKLQEIPKVAKYEPLVNNLSSLFQTLIRYLFYYNSDTFIIPSCWSQLKGHLKKIIDMSNAQVSEQFKLITYRNESLMIDETGKSGLNASSGVEYNRTLTLVHQLNNMSKSTNLKDLVKLIFVDSSSEDNSLEHSDWKQLLKLLLKWTVTIYREESKDAQKIACTRSILKIRIHELSRLKSKKFKLVKQELELEIMGFVYEMAELLNFGNDNNAFNLVQVLRLTNELYSLDLFSVPSYLRRLIASGVIYLQDADKSCYIHLLILNSLPGLQDSNSRNILKRLSDSTNILLPDKNDHLAKERLRKLLDYVFQQSQEFDLYELNDILQYKDDVDPLELGKRVAIEAWFLNEFKEYLRNFSYSFSITHGNLTILNMIFSYKFNMAPQFIGLIVRHLDKTSSTIDQTALTFLLKVISYNDELLLSCISDDVLSGHQNSSPTSQSQLQQIDITSNMFHDIYCILMKWCNSNKFDITHVFELAKFNKYLIPVSLKDETAKYMERKKIINKPQKSAISLEELNQLGISSYERLTNAAEYSHHLSQTINQYWNSIKGFNTDSQSSVISLLKILQNWKPEDFSTTLLLHLRKLILPTLSLEYDLSLKFVLKLVVEGFIDLQSVIQILGKNKSKDEFSTDCNEKLIWDLLFSNTNESILSDFELFSLSFEKKVYRRENPEEYFNFLSVIFREPATPMEETQSSAHDVDIVHVGVDDVVSADVMNSLHDLSNVSVAQTPPGNAVTGVDSNIGHHHHHQIINKEESKINKFNDLVIDSIWYLTFTHMDLFVELFYKNDLNKPEIKELFTVMLDIKASDADGWIYDDLIRNLNYFNLPVSQLLFKILIEEEVSNITDDYELSAKVTQIILQILNQLKGKYNDFHLIGELFEFLDDKLKLKILYACEEIYFGSETFPKLTVNGQNLTNFLIDILTSCSRLKDHNHSVIPLSDSLVFSLNLSLERLMYFSSSLDHKKNKSELVRDLETSIMLLSRIILVHKNFLVELILKRSVNFQRDVFLINLTKLFNHRVMDKRYKLKNLLYDILISLKILISETLSQNVAPTQNFNSVPQGYSQQYSVTTPQQAALITSLSINKGTPSSTSYQSPPGHSPMPPPGSGMTTNAASASLLSSSSNGGFMSGNGGLMNVTPPNYNNKLKFMLQSPTFDHLKDTLIENEKKYFLIDSGTTTGIGPGTGNMIRFNLKSFELIEDSSTTVGLNDSCISLQYFDACIEKKNPR
Length1598
PositionKinase
Organism[Candida] arabinofermentans NRRL YB-2248
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Pichiaceae> Ogataea> Ogataea/Candida clade.
Aromaticity0.09
Grand average of hydropathy-0.252
Instability index40.43
Isoelectric point7.13
Molecular weight182743.12
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10245
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.27|      49|     128|     990|    1047|       1
---------------------------------------------------------------------------
  990- 1047 (75.19/48.95)	QILGKNKSK.DEFStDCNEKLIWDLLFSNtnesilsdFELFSLSFEKKVYRRENPEEYF
 1121- 1170 (81.08/37.31)	QIINKEESKiNKFN.DLVIDSIWYLTFTH........MDLFVELFYKNDLNKPEIKELF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.61|      21|      21|     305|     325|       2
---------------------------------------------------------------------------
  282-  303 (25.72/14.30)	SNCFVPA..NRSTWrykLNYFIEL
  305-  325 (38.25/25.23)	GNLYLQNLMNRETF...LSWIVHY
  327-  347 (32.64/20.33)	GRLIHKDCTDLQGF...KTLSVHY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.25|      17|      22|     612|     628|       4
---------------------------------------------------------------------------
  612-  628 (28.49/15.03)	YLRRLIASGVIYLQDAD
  632-  648 (26.71/13.65)	YIHLLILNSLPGLQDSN
  652-  668 (26.05/13.13)	ILKRLSDSTNILLPDKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.45|      22|      22|    1325|    1346|       5
---------------------------------------------------------------------------
  550-  566 (17.52/ 6.19)	...LSR..LKSKKFK..LVKqELE
 1325- 1346 (38.29/22.56)	LMYFSS.SLDHKKNKSELVR.DLE
 1349- 1367 (20.64/ 8.65)	IMLLSRiILVHKNFLVELI.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.68|      21|      22|    1505|    1525|       6
---------------------------------------------------------------------------
 1498- 1512 (18.90/ 6.35)	.......FMSGNGGLMNVTPPN
 1513- 1533 (34.24/17.06)	YNNKLK.FMLQSPTFDHLKDTL
 1534- 1555 (28.54/13.07)	IENEKKyFLIDSGTTTGIGPGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     226.16|      78|     134|    1237|    1320|       7
---------------------------------------------------------------------------
 1237- 1320 (119.55/102.62)	LKGKYN...DFHLIG..ELF..EFLDDKLKLK.ILYaceEIYFGSETFPKLTVNgQNLTNflIDILTSCSRLKDHNHSV.IPLSDSLVFSLNL
 1368- 1454 (106.61/72.37)	LKRSVNfqrDVFLINltKLFnhRVMDKRYKLKnLLY...DILISLKILISETLS.QNVAP..TQNFNSVPQGYSQQYSVtTPQQAALITSLSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.77|      19|      40|     188|     207|       9
---------------------------------------------------------------------------
  188-  207 (30.60/23.62)	REMWLKNLADPNIPlKQLSR
  231-  249 (34.18/21.62)	RAIWLIRCVSTNEQ.RQLKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.81|      39|      49|     673|     711|      11
---------------------------------------------------------------------------
  673-  711 (66.60/40.53)	KERLRKLLDYVFQQSQEFDLYELNDILQYKDDVDPLELG
  725-  761 (65.94/40.05)	KEYLRN.FSYSFSITHG.NLTILNMIFSYKFNMAPQFIG
  898-  927 (41.26/22.18)	.ERLTNAAEYSHHLSQTINQY.WNSIKGFNTD.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.34|      17|      21|     480|     496|      12
---------------------------------------------------------------------------
  480-  496 (27.57/18.25)	NNMSKSTNLKDLVKLIF
  503-  519 (28.77/19.43)	DNSLEHSDWKQLLKLLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10245 with Med12 domain of Kingdom Fungi
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