<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10230

Description Uncharacterized protein
SequenceMSKSRNRNSLLSSHNRSSYTNSAKDELMAMKYVMNKPDLPLYPLNDADSAIESHSKDSSGVEPSDTNHTYPDYNPWKDHTHLPEDKKQQELQRLSNPNFLNKGYFETPIVSNEYYSARNLIQATIFSSTDNCNNVLKELSQHLTNGYKTRNEVINKIRANSNNFKIPPRVTLTITKKESWLKDLANPSIPLLKISDKLPHGIRNKVLIESVCNKGVPMTRAIWFTKCVLYGELITIRKKHQIRGSGVSTEDFEAHWLKEWTQQVSDYIYKYSKEMGNISSQEKKTSYMNKLNYLLQYVQTLYVECLLDKTFFLSLILKFLKEGLPLQSKHINELMIYSRNEGDESEDDEINDLMLDENHKWITELDLNYGLRLVCLTMMKIFWNDILKFDYLCKEVSELLLLNHYFISKISFLNNKTNFRNLSDGLNQKLLALISDHVTFLFELNTNVFILPNFWVLINSTLYKILKDGEKGRSNQENEEIQGQLELIKYRNESLVLNMRQSTSLANSMTKLSSLPGQQSNAEVEESDHTFINRSSNDILRFIQQLDGLKLGALAEILRPEGTYRTESNELSQLSASLKSTLPSWRIGLSIIIHWSVSSYRCMRKSSENILIICNFLKRQVLQSFSKTSKSSINLKIEFENEILEIIYSIVESEPSTIINYNLYVLINELYQLKIITISSYLRKLIASGIFYLTPEDVTSGQNQLAQMHLNILQNLPVLNNRQCDSILKKWIPNGFNFKEKFEMGKNVLEKEILGLVSSNTKDSENMASYKVNIDSPDYPLHYIKDLNVGLKFLLVNWVTNELKSNVTKSPKLVHITPFTITSLYNFYSLCDNLTVFFKVLIKFILKNDSGMIIFYMDSLYLVARLVLRHFKLIKFMGGTGSTVTNGSESSSAYELFKLIVLNYKDQSTREFDYFKFEGIWNFIDNAIEKKQIEPELGKPKRQLDGDNETDSPLKITSDTKQDGKSFEYSYTNFKEDLDRLTTATSNYLSDQEVLDILDTLHLETELDKHHDSLATDGLTSPSNDEHLHEAQLLNRVLDYYFKHLPELSEENESLIVKIMANIQNKLRYDETLFRTCIQNFISLLLSLADSDHLILFVKKLCLFELVNIKDIINFFQDTNEDTANDKIAEEITYKLLLEEKNEDMPCSQLLLLNLVRDTFKFRNTSTHTFTILKGLRVGDSIFSTILFVLYKEPTLSFLNHLAVTNTKLFLDELILKIPTKDSIELLNILLGWKESQYVQTLGDFSKVVSRIEEFNLPLAQVLLRRICSQELFELPKSEIQFRMKTLVESFVGNLHFDFTSRNSYFGELFNYLIWDHKVCVLNILEDLVLLNTNFVTESSPRISLLVKSSGDEINLLPVLNDFFKKFSTSSTNVVGSSGGLFQNLQNFLTKLVEVTLSIGSKDNEHENISNAVSILLRILIIHKATLTKKIVSQDGEHFLFIKNLIKLLKSTFLQHGNEKLCILLYDLLLLLKTSLTEVLTLNLELDLSEGTSPGFNMGSIEETPKVDTNNDQEWNVTPTAPATTPGGLLATPNATATPGVVATPVINLQGNPSAHLSSIFNLPEPVQQNPFKEYLNSKIDSVLTLDEFELQRSGDIHVANESNLALVPTNQDSSSLSNALGILSNSVRSSNVKVQSYYPYKLRSFEILEDSSQGLNDSCINLQLFDAYTTRENPP
Length1676
PositionKinase
OrganismSuhomyces tanzawaensis NRRL Y-17324
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Suhomyces.
Aromaticity0.09
Grand average of hydropathy-0.251
Instability index41.19
Isoelectric point5.69
Molecular weight191880.88
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10230
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.69|      15|      16|     322|     336|       1
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  322-  336 (26.62/17.02)	EGLPLQSKHINELMI
  341-  355 (26.07/16.49)	EGDESEDDEINDLML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.68|      13|      15|    1253|    1265|       2
---------------------------------------------------------------------------
 1253- 1265 (21.90/12.12)	EEFNLPLAQVLLR
 1271- 1283 (22.78/12.91)	ELFELPKSEIQFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     109.28|      25|      69|     295|     319|       3
---------------------------------------------------------------------------
  295-  319 (43.65/24.07)	LQYVQTLYVECLLDKTFFLSLILKF
  367-  389 (41.80/22.75)	LNY..GLRLVCLTMMKIFWNDILKF
  393-  410 (23.83/ 9.90)	CKEVS....ELLLLNHYFISKI...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.61|      14|      19|    1109|    1122|       4
---------------------------------------------------------------------------
 1109- 1122 (24.74/16.12)	IKDIINF...FQDTNED
 1128- 1144 (17.87/ 9.31)	IAEEITYkllLEEKNED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.65|      15|      19|    1156|    1174|       5
---------------------------------------------------------------------------
 1156- 1174 (18.11/26.11)	VRDTFkFrntSTHTFTILK
 1178- 1192 (26.54/17.79)	VGDSI.F...STILFVLYK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.77|      53|     200|     556|     648|       9
---------------------------------------------------------------------------
  558-  611 (86.88/91.68)	LRPEGTyRTESNELSQLSASLKSTLP..SWRIGLSIIIHWSVSSYRCMRK..SSENIL
  693-  749 (84.89/50.17)	LTPEDV.TSGQNQLAQMHLNILQNLPvlNNRQCDSILKKWIPNGFNFKEKfeMGKNVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     215.81|      56|     202|     995|    1050|      10
---------------------------------------------------------------------------
   48-   87 (61.10/33.09)	.........DSAIESH....SKDSSGV.EPSDTNHTYPD..Y......NPWKDH..THLPEDKK
   88-  145 (62.02/33.70)	QQELQRLSNPNFLNKGYfeTPIVSNEYYSARN...LIQATIFsstdncNNVLKELSQHLTN...
  995- 1050 (92.69/54.20)	LDILDTLHLETELDKHH..DSLATDGLTSPSNDEHLHEAQLL......NRVLDYYFKHLPELSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.48|      28|     140|    1286|    1338|      12
---------------------------------------------------------------------------
 1286- 1313 (49.07/47.82)	TLVESFVGNLHFDFT....SRNSYFGELFNYL
 1358- 1389 (42.41/ 9.54)	PVLNDFFKKFSTSSTnvvgSSGGLFQNLQNFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.58|      21|     140|    1316|    1338|      13
---------------------------------------------------------------------------
 1316- 1338 (32.14/26.35)	DHKVCVLniLEDLVLLNTNFVTE
 1458- 1478 (35.45/22.02)	NEKLCIL..LYDLLLLLKTSLTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.35|      26|     705|      21|      46|      15
---------------------------------------------------------------------------
   21-   46 (48.16/32.90)	NSAKDELMA.MKYVMNKPDLPLYPLND
  760-  786 (44.19/29.53)	NTKDSENMAsYKVNIDSPDYPLHYIKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10230 with Med12 domain of Kingdom Fungi
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