<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10211

Description Rxt3-domain-containing protein
SequenceMREIPENINTTIPSTLRGTGFCIHNTLKKSMSNNDTNIARNPRGNLSFLMDAPEKSNPSSDASGVGQGTGIRLPPISFLNNITQVSGSQVKIPKLLNNIDSPMSQPTVTQTEAFTPAQSQAQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVESLPIVTSKLTPPVQFTFSTQKTSPRTLPLKEEITKPDIDSESDEEIIKYYEKKYGINDFTDEEKHDILQHERRARIEKHKNPNYKTYLCYSIIKRLNAVKPTKPSVKEEGAKKKEPPSKKQPAQSTPVISTVSTVSKKAEAPRPTVKKDIIVDNSDVLTYASKFPRTHLGSLIYTPFPRRESYRQLNIFKDVKFLNNDIVPLIPELREYVNSIITVRIPSWLIGDLKNNKNYQHRAIWGTDIYTDDSDILMILKHNGFLPAVDEELEQEEIKMKKQTPGNLTNKSNIVQSVPNFRQFVNIIGGDIHVDLIVLPPLVKYTGVYRNGVNSRSWKGHDGMSLALYGVRYGEKGSSVDDMNDVGTKKRRLDEIVEQSQNVKGEAWKIDKTAWKRVKEQ
Length550
PositionTail
OrganismCyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / CCRC 20928 / JCM 3617 / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Phaffomycetaceae> Cyberlindnera.
Aromaticity0.06
Grand average of hydropathy-0.795
Instability index56.52
Isoelectric point9.29
Molecular weight62556.03
Publications
PubMed=27535936

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process
histone deacetylation	GO:0016575	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP10211
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.02|      15|      15|     122|     136|       1
---------------------------------------------------------------------------
  122-  136 (31.85/15.32)	QIQQQQQQQQQQQQQ
  138-  152 (32.17/15.53)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.32|      13|      15|      78|      90|       2
---------------------------------------------------------------------------
   78-   90 (22.79/13.45)	FLNNI.TQVSGSQV
   95-  108 (19.53/10.54)	LLNNIdSPMSQPTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.64|      16|      87|     354|     369|       3
---------------------------------------------------------------------------
  354-  369 (28.57/19.10)	DIVPLIPELREYVNSI
  442-  457 (29.08/19.58)	NIVQSVPNFRQFVNII
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.10|      16|      91|     294|     314|       4
---------------------------------------------------------------------------
  299-  314 (27.84/26.15)	RPTVKKDIIVDNSDVL
  391-  406 (30.25/15.28)	RAIWGTDIYTDDSDIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.14|      11|      15|     191|     201|       5
---------------------------------------------------------------------------
  191-  201 (19.62/12.44)	KPDIDSESDEE
  209-  219 (20.52/13.34)	KYGINDFTDEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.24|      17|     267|      36|      53|       6
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   10-   26 (31.63/21.74)	TTIPSTLRGT.GFCIHNT
   36-   53 (26.61/22.56)	TNIARNPRGNlSFLMDAP
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP10211 with Med15 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) IHNTLKKSMSNNDTNIARNPRGNLSFLMDAPEKSNPSSDASGVGQGTGIRLP
2) PTKPSVKEEGAKKKEPPSKKQPAQSTPVISTVSTVSK
3) VKIPKLLNNIDSPMSQPTVTQTEAFTPAQSQAQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVESLP
4) VQFTFSTQKTSPRTLPLKEEITKPDIDSESDEEII
23
257
90
169
74
293
159
203

Molecular Recognition Features

MoRF SequenceStartStop
1) KIDKTAWKRV
2) YKTYLCYSIIKRL
538
240
547
252