<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10206

Description Uncharacterized protein
SequenceMYGSKTTAVKPQRAQSSRDELINNRYNLSEPEGVYPLDGSHSGINKYPDFQPWKHTIKEDHIAVDHLQRGYFESPQVGNELLSARNIMHQLLRSKNSLESLSSNVLMAMDLRARNNRVGPGTYKPPPRVTLTDQKRENWLKDLANSEVPLRKLARTIPHGVRNKTLIEQCVSKKIPITRAIWFVRCVSTNELRGLKRKGGANIEYTWVQEWTTQVLEFIEKLSHDYLKFESFQQAKESWKTNVSYLLRFVSNLYIENLVDKDSIKFWILKFFKLCKIYELPLALTIIKMFWNEISKTDYIIKEITETIILRYSVVSSCKNLLEAKDIIITDQQLNDNIKSKIMKELKFLLMNSFSQSIDNFILPNNWDQLSPIIGDILDLTDSKTKKKFDIINYRNESLMINYSLNKNREVRDVISVLDKLEGEIDYDNIISLILKDDWKFNVKLVLQWSLTRFRYRTSRVYLFTELCKRLKTHPSVSLKALEQEILESVFSLSLNPTDLILDDLFLLLNQLIQIKVFKVPIYLRRLISSGLIYQNDNHLEKQVHASILMNLKPQKGSQTSLILKNLSEFNGEGMDYDEMIKLGLSILHDNSDRTLENLHFLKSMPVGVKLQLSELYLSKILERENLFPLITYTELRKILETLLSLGDMNSVTRLIVKALDSQNLEREEFLLLTECILTNLQLVSFIVNIDDIVLSILQNSNRLMLSTSMIKFWQAFNKSFKSKYSDDIEKNINQKGVEYDLATIMMAISESELGITYDQLIQESSFHNNFQVLIRSLFNNTSCDSKGKAIIILMKVLKFHNTAEFNRIVFVHIKKTYSSSTELLKYEPLWDIIIYDLVSVQMIFETFLSFNSQIHLSFILDLLFKESTPSEPHDFFKLSLLREQFKRENPKTMINLIKMSLSESDIKMESIQSDSADIINTIMDNTTSSTYKSEQLAVFLDILISDQKMVVAAIENEDDALKNKIIIWLNETIFNRPEDIAIDYICASRLVENIKRENRFNLPLMQLLFKLKLNQNIPEDDLVTVLKAVILRSTKEKTLSFIFELLDVPLKIKLIHFLEMIFLSSPSFPSVNINDQRLDLTCLSDSLVALSSGTQNVTLSDELVFSLDVSLDHLNKVIAQGDRDVQVLYSAISLFLKIIIIHKGFLINILIERNTIKESFLNNLVNLLSTTVVSSNLKLKNLLYDLILSIKSSINEINSSQVHNVKLPVSIINLPSISSNAGKSKAALVNKQNLHDFNCVLDLYLYHKTTCSFHEFNIKPFDMVEDSNPIENLNDTAVSLQLFEASIERKNPT
Length1294
PositionKinase
OrganismCyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / CCRC 20928 / JCM 3617 / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Phaffomycetaceae> Cyberlindnera.
Aromaticity0.09
Grand average of hydropathy-0.106
Instability index41.24
Isoelectric point6.60
Molecular weight149394.29
Publications
PubMed=27535936

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10206
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     562.28|     107|     195|     197|     303|       1
---------------------------------------------------------------------------
  197-  303 (176.10/105.77)	RKGGANIEYTWVQEWTTQ.VLEF.IEKLSH..DY.LKFESF....QQAKESWKTNVSYLLRFVSNLYI...ENLVD...KDSIKFWIL..KFFKLCK.IYELP......LALTII.KMFWNEISK......TDY.IIKE
  309-  394 (71.57/38.13)	...................ILRYsVVSSCK..NL.LEAKDIiitdQQLNDNIKSKIMKELKF...LLM...NSF.....SQSIDNFILpnNWDQLSP.IIGDI......LDLTDS.K......TK......KKFdIINY
  395-  504 (103.65/58.89)	RNESLMINYSLNKNREVRdVISV.LDKLEGeiDY.DNIISL.....ILKDDWKFNVKLVLQW..........SLTRfryRTS.RVYL....FTELCKrLKTHPsvslkaLEQEILeSVFSLSLNP......TDL.ILDD
  506-  582 (73.15/39.15)	.................................F.LLLNQL....IQIK.VFKVPI.YLRRLISSGLIyqnDNHLE...K.QVHASIL..MNLKPQK.GSQTS......LILKNL.SEFNGEGMD......YDE.MIK.
  592-  658 (69.10/36.53)	............SDRTLE.NLHF.LKSMPV..GVkLQL.........................SELYL...SKILE...RENL.FPLI..TYTELRK.ILETL......LSLGDM.N......SV......TRL.IVK.
  660-  732 (68.71/36.28)	...........................LDS..QN.LEREEF....LLLTECILTNLQ.LVSFIVNI..............DDIVLSIL..Q.....N.SNRLM......LSTSMI.K.FWQAFNKsfkskySDD.IEKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      61.73|      15|      16|     850|     864|       2
---------------------------------------------------------------------------
  850-  863 (18.91/ 8.67)	....SFNSQIHLSFILDL
  864-  881 (21.76/11.19)	LfkeSTPSEPHDFFKLSL
 1047- 1061 (21.05/10.57)	L...DVPLKIKLIHFLEM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.33|      57|     173|     733|     808|       3
---------------------------------------------------------------------------
  733-  753 (16.15/ 6.19)	......................................................................................INQKGVEYDLATIMMAI...SESE
  759-  808 (32.38/46.60)	DQLIQEssfhnnfQVLIRSLFNNTSCDSKGKaIIILMkvlkfhNTAEFNR............................................................
  942- 1037 (68.80/37.77)	DILISD.......QKMVVAAIENEDDALKNK.IIIWL......NETIFNRpediaidyicasrlvenikrenrfnlplmqllfklkLNQNIPEDDLVTVLKAVilrSTKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.23|      32|     122|    1064|    1097|       5
---------------------------------------------------------------------------
 1064- 1097 (50.00/34.63)	LSSPSfpSVN.INDQRLDLTCLSDSLVALSSGTQN
 1189- 1221 (48.23/26.52)	LSIKS..SINeINSSQVHNVKLPVSIINLPSISSN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10206 with Med12 domain of Kingdom Fungi
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