<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10206

Description Uncharacterized protein
SequenceMYGSKTTAVKPQRAQSSRDELINNRYNLSEPEGVYPLDGSHSGINKYPDFQPWKHTIKEDHIAVDHLQRGYFESPQVGNELLSARNIMHQLLRSKNSLESLSSNVLMAMDLRARNNRVGPGTYKPPPRVTLTDQKRENWLKDLANSEVPLRKLARTIPHGVRNKTLIEQCVSKKIPITRAIWFVRCVSTNELRGLKRKGGANIEYTWVQEWTTQVLEFIEKLSHDYLKFESFQQAKESWKTNVSYLLRFVSNLYIENLVDKDSIKFWILKFFKLCKIYELPLALTIIKMFWNEISKTDYIIKEITETIILRYSVVSSCKNLLEAKDIIITDQQLNDNIKSKIMKELKFLLMNSFSQSIDNFILPNNWDQLSPIIGDILDLTDSKTKKKFDIINYRNESLMINYSLNKNREVRDVISVLDKLEGEIDYDNIISLILKDDWKFNVKLVLQWSLTRFRYRTSRVYLFTELCKRLKTHPSVSLKALEQEILESVFSLSLNPTDLILDDLFLLLNQLIQIKVFKVPIYLRRLISSGLIYQNDNHLEKQVHASILMNLKPQKGSQTSLILKNLSEFNGEGMDYDEMIKLGLSILHDNSDRTLENLHFLKSMPVGVKLQLSELYLSKILERENLFPLITYTELRKILETLLSLGDMNSVTRLIVKALDSQNLEREEFLLLTECILTNLQLVSFIVNIDDIVLSILQNSNRLMLSTSMIKFWQAFNKSFKSKYSDDIEKNINQKGVEYDLATIMMAISESELGITYDQLIQESSFHNNFQVLIRSLFNNTSCDSKGKAIIILMKVLKFHNTAEFNRIVFVHIKKTYSSSTELLKYEPLWDIIIYDLVSVQMIFETFLSFNSQIHLSFILDLLFKESTPSEPHDFFKLSLLREQFKRENPKTMINLIKMSLSESDIKMESIQSDSADIINTIMDNTTSSTYKSEQLAVFLDILISDQKMVVAAIENEDDALKNKIIIWLNETIFNRPEDIAIDYICASRLVENIKRENRFNLPLMQLLFKLKLNQNIPEDDLVTVLKAVILRSTKEKTLSFIFELLDVPLKIKLIHFLEMIFLSSPSFPSVNINDQRLDLTCLSDSLVALSSGTQNVTLSDELVFSLDVSLDHLNKVIAQGDRDVQVLYSAISLFLKIIIIHKGFLINILIERNTIKESFLNNLVNLLSTTVVSSNLKLKNLLYDLILSIKSSINEINSSQVHNVKLPVSIINLPSISSNAGKSKAALVNKQNLHDFNCVLDLYLYHKTTCSFHEFNIKPFDMVEDSNPIENLNDTAVSLQLFEASIERKNPT
Length1294
PositionKinase
OrganismCyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / CCRC 20928 / JCM 3617 / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Phaffomycetaceae> Cyberlindnera.
Aromaticity0.09
Grand average of hydropathy-0.106
Instability index41.24
Isoelectric point6.60
Molecular weight149394.29
Publications
PubMed=27535936

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10206
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     562.28|     107|     195|     197|     303|       1
---------------------------------------------------------------------------
  197-  303 (176.10/105.77)	RKGGANIEYTWVQEWTTQ.VLEF.IEKLSH..DY.LKFESF....QQAKESWKTNVSYLLRFVSNLYI...ENLVD...KDSIKFWIL..KFFKLCK.IYELP......LALTII.KMFWNEISK......TDY.IIKE
  309-  394 (71.57/38.13)	...................ILRYsVVSSCK..NL.LEAKDIiitdQQLNDNIKSKIMKELKF...LLM...NSF.....SQSIDNFILpnNWDQLSP.IIGDI......LDLTDS.K......TK......KKFdIINY
  395-  504 (103.65/58.89)	RNESLMINYSLNKNREVRdVISV.LDKLEGeiDY.DNIISL.....ILKDDWKFNVKLVLQW..........SLTRfryRTS.RVYL....FTELCKrLKTHPsvslkaLEQEILeSVFSLSLNP......TDL.ILDD
  506-  582 (73.15/39.15)	.................................F.LLLNQL....IQIK.VFKVPI.YLRRLISSGLIyqnDNHLE...K.QVHASIL..MNLKPQK.GSQTS......LILKNL.SEFNGEGMD......YDE.MIK.
  592-  658 (69.10/36.53)	............SDRTLE.NLHF.LKSMPV..GVkLQL.........................SELYL...SKILE...RENL.FPLI..TYTELRK.ILETL......LSLGDM.N......SV......TRL.IVK.
  660-  732 (68.71/36.28)	...........................LDS..QN.LEREEF....LLLTECILTNLQ.LVSFIVNI..............DDIVLSIL..Q.....N.SNRLM......LSTSMI.K.FWQAFNKsfkskySDD.IEKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      61.73|      15|      16|     850|     864|       2
---------------------------------------------------------------------------
  850-  863 (18.91/ 8.67)	....SFNSQIHLSFILDL
  864-  881 (21.76/11.19)	LfkeSTPSEPHDFFKLSL
 1047- 1061 (21.05/10.57)	L...DVPLKIKLIHFLEM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.33|      57|     173|     733|     808|       3
---------------------------------------------------------------------------
  733-  753 (16.15/ 6.19)	......................................................................................INQKGVEYDLATIMMAI...SESE
  759-  808 (32.38/46.60)	DQLIQEssfhnnfQVLIRSLFNNTSCDSKGKaIIILMkvlkfhNTAEFNR............................................................
  942- 1037 (68.80/37.77)	DILISD.......QKMVVAAIENEDDALKNK.IIIWL......NETIFNRpediaidyicasrlvenikrenrfnlplmqllfklkLNQNIPEDDLVTVLKAVilrSTKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.23|      32|     122|    1064|    1097|       5
---------------------------------------------------------------------------
 1064- 1097 (50.00/34.63)	LSSPSfpSVN.INDQRLDLTCLSDSLVALSSGTQN
 1189- 1221 (48.23/26.52)	LSIKS..SINeINSSQVHNVKLPVSIINLPSISSN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10206 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA