<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10186

Description GAL11-domain-containing protein
SequenceMNNLQQPQNMGSTWHSMYSPQDRQKVIQIVLSTLKDIQGNNYDAQKAQTMAQEFEKFTFMKAPSRDEYLRSIKQKITQLRSGSMRNMAAASAAANPNNIANNNNNNNTNNNINAPARNPTVPNNTAGMVNNVGPQNNMNHQSMNFLQQQAQARQQSAAQIQAQMRNNQQQQQQPPSQPQQPPTQQPQQPQGSNQGPNQGSMNNTGLQQNSQIQQIISNMIKNVPIPQALLSKIPNLPPNCNTWTQIFDCFQKKIIPHSAMPVIRDIHNTHMQFALRQHQQQRLNQFQKNQQPQQSQQQGNQNTQQNNQNKLNLPAGLPANFNLNNLTPQQKQQLLQRQLQQQQQNNNNNALQNQQKTQPQPVPQNDQNQIPPQSQQPQQPQQPQNQQGLQGQQQARPANTTITPEDIVRYSSDALTLLATLQNNGSIPRELDQNQKQSFIRKYIHHQKLSLWKQQQRNNLNIPPNQAIATNSNDAVNQAQIQRRLQAQAEAQAQQQNQQGQQGQANQGLASQIPSVSPATAFQPQPQPQGQPGVNGINNVPPQQLPLINNMHIPNQQIMRPQGQMNNLSSPLMQQRGLAPTPAMNNANLNNANAAFNPNAPSTSVPPTNPSAQAGGTNQQPPQPQGIPGAGGRPNTTANPINNILPPLNDEMKVRLRKLFEEVSRNTVPLRDVTLLLSPQDKKAVGETLAKISQQYANVDTILSYFYVLTKNLEGTKRLIQMKHMTRNIVDNLRRGVYLAGPDLLEKLRTQYQKYFDYVKEQIAMRRQLQQRQGQQRQGANGAPGSQQSPQFMNNQLNGTVPMPNQISPQLRNAMIPDQNQRNNMRPQANWNNMGKPVIGQQAPQAPIPTQPQMQQGQLPQGIQPTPNLQPRLRPQSGAFNSSPMMPNMASPMMANTVMPNAQQPAFQQTPQQQPAPTPSMKAKDLAAAQKKSISGPGSGRRKGSTKATQAAQAAQVAAANISTPAAAVVTPATLANTIKTPNSIPTPQVPQTHSNKNTPTGQSPNYPNKPSSSSSILVNKDAAVGDIFNHSGADSKLARRRELSNSDPEKFFYASLANLLELPDPEGTANNSKGSSIDMLNTPISIGSVASTTSNQANSTTTGGTTANSSPLVNGKSNAKSPLSPHNVNSSNQWTCEIRPDAIVSAFRQVDGIRELAANDIISTCSHLAELESQSKSQVPTRDEGNATTGNLESQGIKRENDQMEDFDDIEGLFDEKKIKLDDISHNQFMFEPVAFDDWKQFVVTSLQ
Length1249
PositionTail
OrganismHyphopichia burtonii NRRL Y-1933
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Hyphopichia.
Aromaticity0.04
Grand average of hydropathy-0.927
Instability index58.82
Isoelectric point9.92
Molecular weight137736.92
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10186
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     418.42|      42|      42|     465|     506|       1
---------------------------------------------------------------------------
  118-  159 (50.01/ 8.95)	NPTVPNNTAGMV.....N.NVGPQNNMNHQSMNFLQQ.QAQARQQSA.....AQ
  160-  193 (48.03/ 8.26)	IQAQMRN..........N.QQQ.....QQQPPSQPQQpPTQQPQQPQ....gSN
  316-  354 (46.40/ 7.68)	GLPANFNLNNLT.....P.Q.QKQQLLQRQ..LQQQQ.QNNNNNALQ.....NQ
  357-  399 (55.08/10.72)	TQPQPVPQND.........QNQIPP..QSQQPQQPQQpQNQQGLQGQqqarpAN
  465-  506 (71.87/16.60)	NQAIATNSNDAV.....N.QAQIQRRLQAQAEAQAQQ.QNQQGQQGQ.....AN
  585-  625 (46.76/ 7.81)	NNANLNNANAAF.....NpNAPSTSVPPTNPSAQAGG.TNQQPPQPQ.......
  786-  824 (47.02/ 7.90)	SQQSPQFMNNQL.....N.GTVPMP...NQISPQLRN.AMIPDQNQR.....NN
  827-  868 (53.24/10.08)	PQANWNNMGKPVigqqaP.QAPIP....TQPQMQQGQ.LPQ.GIQPT.....PN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     338.80|      61|     345|     522|     584|       2
---------------------------------------------------------------------------
  206-  258 (70.65/19.63)	LQQNSQIQ..QI..ISNMIKNVPiPQAL.L...SKIPN..L.P.......P....NcNTWTQIFDcfQKKIIPHS
  522-  582 (118.55/39.84)	FQPQPQPQ.GQP..GVNGINNVP.PQQLPLINNMHIPNQQIMR.......PQGQMN.NLSSPLMQ..QRGLAPTP
  628-  689 (63.68/14.14)	....PGAG.GRPntTANPINNIL.P...PLNDEMKVRLRKLFEevsrntvPLRDVT.LLLSP.QD..KKAVGETL
  869-  919 (85.92/26.07)	LQPRLRPQsGAF..NSSP..MMP.NMASPMMANTVMPNAQ..Q.......PAFQ.....QTP.QQ..Q.P.APTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.39|      19|      19|     977|     995|       3
---------------------------------------------------------------------------
  983- 1000 (32.79/13.65)	NSIPTPQVPQTHS.NK.NTP
 1046- 1064 (24.79/ 8.48)	NSDPEKFFYASLA.NLLELP
 1065- 1084 (21.81/ 6.56)	DPEGTANNSKGSSiDMLNTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.01|      21|     174|     263|     284|       4
---------------------------------------------------------------------------
  263-  284 (35.80/20.84)	IRD.IHNTHMQfALRQHQQQRLN
  440-  461 (32.21/13.62)	IRKyIHHQKLS.LWKQQQRNNLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.25|      16|      48|     705|     721|       6
---------------------------------------------------------------------------
  702-  718 (22.71/19.34)	ILSYFYvLTKN..........LEGTKR
  719-  744 (19.54/10.43)	LIQMKH.MTRNivdnlrrgvyLAGPDL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10186 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) APSRDEYLRSIKQKITQLRSGSMRNMAAASAAANPNNIANNNNNNNTNNNINAPARNPTVPNNTAGMVNNVGPQNNMNHQSMNFLQQQAQARQQSAAQIQAQMRNNQQQQQQPPSQPQQPPTQQPQQPQGSNQGPNQGSMNNTGLQQNSQIQQIISNM
2) ESQSKSQVPTRDEGNATTGNLESQGIKRENDQMEDFDD
3) HSAMPVIRDIHNTHMQFALRQHQQQRLNQFQKNQQPQQSQQQGNQNTQQNNQNKLNLPAGLPANFNLNNLTPQQKQQLLQRQLQQQQQNNNNNALQNQQKTQPQPVPQNDQNQIPPQSQQPQQPQQPQNQQGLQGQQQARPANTTITPEDIVR
4) LLATLQNNGSIPRELDQNQKQSFIRKYIHHQKLSLWKQQQRNNLNIPPNQAIATNSNDAVNQAQIQRRLQAQAEAQAQQQNQQGQQGQANQGLASQIPSVSPATAFQPQPQPQGQPGVNGINNVPPQQLPLINNMHIPNQQIMRPQGQMNNLSSPLMQQRGLAPTPAMNNANLNNANAAFNPNAPSTSVPPTNPSAQAGGTNQQPPQPQGIPGAGGRPNTTANPINNILPPL
5) LPDPEGTANNSKGSSIDMLNTPISIGSVASTTSNQANSTTTGGTTANSSPLVNGKSNAKSPLSPHNVNSSN
6) RRQLQQRQGQQRQGANGAPGSQQSPQFMNNQLNGTVPMPNQISPQLRNAMIPDQNQRNNMRPQANWNNMGKPVIGQQAPQAPIPTQPQMQQGQLPQGIQPTPNLQPRLRPQSGAFNSSPMMPNMASPMMANTVMPNAQQPAFQQTPQQQPAPTPSMKAKDLAAAQKKSISGPGSGRRKGSTKATQAAQAAQVAAANISTPAAAVVTPATLANTIKTPNSIPTPQVPQTHSNKNTPTGQSPNYPNKPSSSSSILVNKD
62
1173
257
417
1063
766
219
1210
409
648
1133
1022










Molecular Recognition Features






MoRF SequenceStartStop




1) AAQVAA
2) KDLAAAQK
954
924
959
931