<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10099

Description Uncharacterized protein
SequenceMPTNSRYPAGTNPYAPSAASKHPASTRGHRPAGSKAPSQHQSQQILPVRKHIVEEAEVEEFEPPRWRTVMHKKVDFGYPDFYPSRPGFGQTEDVLTEENVKNGFTGKLFISEAAETFSMHGPIHQHLTNGCLNMLVQLGKEVIQKQEDTLPQFTDRSFRIPVRVVWNDSKRLAFLSDLANPQIPLHRLMLNQVPHGFKGIELLDAMYSPSTSGGHNRPSAGASQTLSESIPVERAVWFIRVLGANEITAHRARTHQTAAASVTVPSPVAATPSSTNTINASPSLPQGSNDWYTQEFTNIIITWLRGQLAQLALPNTGKAPAKPNTNVKSGGGVLQDAKTRARWLSKWDYSNRLLGELDTKQLLSTRLFAGWLSDHLSHVNLAQLGFLLQVISKHLLDISKHQSSARHCLRAACEKLKELRGSPGKDLLGKVDQALVDIIKTLYIADSDVLLSPATWFQHSALLSSIISPSSLQWGDLQRRNQSLMFTPSAAETSSNPRRQQMEEIRKLDSICENTDMVALANSYFDSSSSACHFPLDLPKIEEKVFNLLNWSMGQFQLGAHRPYAVYTLLKHWYDQHEDYQNRQSRPQMVDLFDVVYKWMDTSSAAKDEDNVQAIGITVGELTRRGMFSYGRYLQNLIANGYTARHQRLDGSCVSHHLALLRVLPIFVMAKDLLQQRRIALSGDSLHARKQDEEEEERMIEIHREQIKEYVPEVFGLASHGQSDQLKAQVDHQLPSSTQMTRYLYVYSRFLTAHKAGEILKAHDGQPSMTASVFARVTQVFRQSRGYATIADFIIRALREAEDPQILDVIIDIIHRDADVWTAMDFWPRLGDKLLDKYHMLEREGKDHERLVDLLRELAVKGRLNEEEEDEVKHLPVNPSQSSKVQKSEAPIADALEALPHVLSSNKDALAVSVVPALFAQNGDFDSWSSTWWATIVDVILRATVDQRSTLNGTLALHVSSVHAQCGHPFNDCVSGWLSGMTPIARLDLFGKKSSEIITRLLLFLVSQRYLSTMVLLEGTVFPIWKQTSAFALPPRKRLSSKMIQAISSSMDVVAQLLVSPPLNPSLPPLSIEESIITQASRQSVLQPPNVISLIQNLPVLVVFSQSRLLPEDMSAKIDDCVKRLGRTAEFKTAAFRNLSVLKDAFLAREWSEPGMEQELEGRMVDALKMIMSEDTLQSSPKGSLPEYDSSTRFSAWRWTRVVLEMRVEFKTLAARIKAPETTAKEVQEARQTLNQLVQATLERETNAEDVDLLAEVFKGVDSVVTQEILAAGMDRLASLLGQAIGAETETQLEAAVKVIDQLLRLLQSTTSYLSTSGTPQFFLDPTIHSSRHKLLDLLALALQSVERHFSTDWEQSLPHGISPPQPGTLLKIVVELLKFTLGTMAGDGSAGGMGVVRPNFGHLSVCFFRAVMAGQHILDESSAKSMADILAYIVDCTPPQSRSASQVSLLGETVSPHTQNTLASFPDLTAALPHLSPVPRSMSLVSLDASADDNTRDNIHINGDAYDLESAMPLDDRKWELFDYLGPSRKAYGPQDMYLASNPLRDQSSIPVSLFHPRMTRDAPPDSGQVRENKDDELPEDGEVKTTALPSPVEEDSGKGKPWERFASERNVGDGLSGEVTGARQLATRLFAVVDDISGEGRGEQESGELLETKKKVTIGRKEKKGSGTSKDPIAFDDANSEESGSEAPAAKKAKTSKTAAGASVAGSDATAPVNGAGRPATSGKAPARKSTGGKTTSKKAAVGKSTKEVTEDKPKAKRRRKSTME
Length1767
PositionKinase
OrganismCryptococcus amylolentus CBS 6039
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Cryptococcus.
Aromaticity0.06
Grand average of hydropathy-0.361
Instability index49.86
Isoelectric point6.41
Molecular weight195244.00
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10099
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     161.87|      36|      36|    1665|    1700|       1
---------------------------------------------------------------------------
 1636- 1663 (31.20/13.85)	........DDISGEGRGEQESGELLETKK.KVTIGRK
 1665- 1700 (57.27/31.45)	KKGSGTSKDPIAFDDANSEESGSEAPAAK.KAKTSKT
 1702- 1732 (33.35/15.30)	...AGAS...VAGSDATAPVNGAGRPATSgKAPARKS
 1733- 1764 (40.05/19.82)	TGGKTTSKK..AAVGKSTKEVTEDKPKAK.RRRKS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.54|      54|     263|     561|     617|       2
---------------------------------------------------------------------------
  561-  617 (92.22/73.24)	HRPYAVYTLLKHW...YDQHED.YQ..NRQSR..PQMVDLF.DVVYKwmdTSSAAKDEDNVQAIGI
  815-  877 (71.32/46.91)	HRDADVWTAMDFWprlGDKLLDkYHmlEREGKdhERLVDLLrELAVK...GRLNEEEEDEVKHLPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.13|      14|      38|     387|     400|       3
---------------------------------------------------------------------------
  387-  400 (22.73/16.60)	LLQVISKHLLDISK
  427-  440 (22.41/16.25)	LLGKVDQALVDIIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.01|      18|      43|     915|     932|       4
---------------------------------------------------------------------------
  915-  932 (36.10/22.81)	VPALFAQNGD.FDSWSSTW
  959-  977 (32.91/20.14)	VSSVHAQCGHpFNDCVSGW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.32|      14|     264|     197|     210|       5
---------------------------------------------------------------------------
  197-  210 (24.37/15.30)	FKGIEL....LDAMYSPS
  457-  470 (23.86/14.81)	FQHSAL....LSSIISPS
  472-  489 (20.09/11.09)	LQWGDLqrrnQSLMFTPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.09|      28|      35|    1418|    1450|       6
---------------------------------------------------------------------------
 1418- 1450 (43.76/32.66)	IldessAKSMADILAYIVDCT...P...PQSRSASQVSL
 1455- 1488 (41.33/21.08)	V.....SPHTQNTLASFPDLTaalPhlsPVPRSMSLVSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.29|      19|      35|    1298|    1316|       8
---------------------------------------------------------------------------
 1298- 1316 (29.69/14.64)	KVIDQLLRLLQSTTSYLST
 1334- 1352 (29.60/14.58)	KLLDLLALALQSVERHFST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.80|      42|     451|    1098|    1167|       9
---------------------------------------------------------------------------
 1125- 1167 (67.84/75.71)	LGRTAEFKTAAFRNlSVLKDAFLAREW....SEPGMEQELEGRMVDA
 1579- 1624 (67.96/28.18)	LPEDGEVKTTALPS.PVEEDSGKGKPWerfaSERNVGDGLSGEVTGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.14|      32|     264|     355|     386|      10
---------------------------------------------------------------------------
   89-  104 (16.66/ 6.18)	...............GQTEDVLTE..EN.VKN.GF
  106-  139 (40.14/27.85)	GKLFISEAAETFSMHGPIHQHLTNgcLNmLVQLG.
  355-  386 (55.34/41.87)	GELDTKQLLSTRLFAGWLSDHLSH..VN.LAQLGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.70|      15|      15|    1263|    1277|      17
---------------------------------------------------------------------------
 1263- 1277 (23.96/18.41)	SVVTQEILAAGMDRL
 1279- 1293 (23.74/18.16)	SLLGQAIGAETETQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.58|      10|      36|    1361|    1370|      18
---------------------------------------------------------------------------
 1361- 1370 (19.97/ 9.41)	GISPPQPGTL
 1395- 1404 (19.60/ 9.10)	GVVRPNFGHL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10099 with Med12 domain of Kingdom Fungi
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