<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10089
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MSLNPNHLPSPAPTPSEALLQPGASTPAPPAAPAVPDQEAIRTAVENQLLQLAQDLYEMEISAGYVRENREDAVPGYLENINKALVNLSQLSSQMTDSVPHQIVEHVDRHKNPHTYTKQAITRATGENQYALGRVLGLESFRRQLHEAVSENFPEVPLPERRHQPIKPPQETNGGGEEGPESAQNVPNGGGAGETGAPDGPAAVNGHHQP |
Length | 210 |
Position | Middle |
Organism | Cryptococcus amylolentus CBS 6039 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes>
Tremellales> Cryptococcaceae> Cryptococcus.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.737 |
Instability index | 59.87 |
Isoelectric point | 5.11 |
Molecular weight | 22531.56 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP10089
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 42.28| 13| 15| 176| 189| 1
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176- 189 (20.73/13.85) GEEG.PESAQNVpNG
193- 206 (21.56/ 9.25) GETGaPDGPAAV.NG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.53| 17| 37| 39| 56| 5
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39- 56 (22.52/20.86) EAIRTAVENqLLQLAQDL
79- 95 (28.02/20.19) ENINKALVN.LSQLSSQM
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