<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10032

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMPSPCSSTVATSSAAASSLHSSKISTLSEASVDSTAQTGHPGIGDLQEELYQMIKSLKDQYFVELNELYNKVSIKIQQIDNQMPAQKSAEQYEKMKGFKGMLERTLHFLQVNKSNIHPGLREKIPIYERQILSILSSQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKSGMYQQLSQRNYYQQIKQGGVFPISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTPGISASPLLAEFTSADGSPANVPTQVPAKSSAAERPLDRLLKALRTTQRESLSAAVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFITHDGSGASKKMKRDTSAMPLNVSSAGSVNDSLKQSYGVGTPELQSTATSRVKWQRAEVNHALMEEIQEINQQLIDTELHVSEDDAESFTTSEGGKGTVIRCTFTAVAVCPSLKSVFASAQMSPILPLRLLVPASYPKCSPVLLDKFPDEQCRNSDDLSTKAKTKFSVLLRGLAEPMSLREIARTWDACARKVITEYAQQTGGGSFSSSYGCWESCVGAC
Length801
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.04
Grand average of hydropathy-0.572
Instability index60.32
Isoelectric point8.89
Molecular weight86548.09
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10032
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.54|      16|      16|     311|     326|       1
---------------------------------------------------------------------------
  290-  305 (25.80/ 9.90)	QQLKQQRQEHQMMQSQ
  311-  326 (31.15/13.60)	QQMMQQIQQKQTLQPQ
  330-  345 (24.59/ 9.07)	QQLKKQQQQGQMQFPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     228.32|      46|      57|     386|     431|       2
---------------------------------------------------------------------------
  158-  206 (47.10/14.14)	APSS.NiSQQLQ...........TSQGLQQ...........HdsHTSQMPQASL.psM.NTG.VQTsGAPAPQG.T...
  208-  263 (52.21/16.35)	FGVP.T.TQQNV...........TNAPQAGsnlenaqgnnfN..H...VQHGSMgaaL.Q.Q.ERT.G.PMQGAlNAQQ
  386-  431 (83.53/29.87)	FPIS.S.PQTLQ...........TSSPQIS...........H..HSPQVDQHSL...L.QSQ.VKT.GTPLHSA.NSPF
  437-  490 (45.48/13.44)	PPVApS.PMPMDsdkplsnlssvTSAGQAG...........H.......QQTSL...ApQTQsIAV.NTPGISA..SPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     409.86|     117|     577|      28|     149|       3
---------------------------------------------------------------------------
   28-  149 (188.88/153.57)	SEASV.DSTAQTGHPGIGDLQEELYQMIKSLKdqyfVELNE.LYNKVS.IKIQQIDNQMP.AQKSAEQYEKMKGFKGMLERTLHFLQVNKsNIHPGLR......EKIPIYERQILSILSSQRRKPV...QAPGQQ
  503-  559 (61.40/37.45)	.....................................................NVPTQVP.AKSSAAERP........LDRLLKALRTTQ.......R......ESLSAAVSDIGSVVSMIDRIAG...SAPGNG
  606-  732 (159.58/114.95)	SAGSVnDSLKQSYGVGTPELQSTATSRVKWQR....AEVNHaLMEEIQeINQQLIDTELHvSEDDAESFTTSEGGKGTVIRCT.FTAV...AVCPSLKsvfasaQMSPILPLRLLVPASYPKCSPVlldKFPDEQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10032 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTP
2) PLLAEFTSADGSPANVPTQVPAKSSAAERPLDRLLKALRTT
3) SQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKS
387
489
137
483
529
365










Molecular Recognition Features






MoRF SequenceStartStop




NANANA