<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10030

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMLSMESQTKTQQNPGNVQVIPNQNPPGPAPGLPPQVSNPAQSSAIPLISQQQTRQSNASTSVQGSLPSLGQNSSSVSQASTLHNMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQKYLNQKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSLHQQQHQQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQTSAGMLLQQNNIDQKQYVQAQRGLQEAPSTSVDSTAQTGHPGIGDLQEELYQMIKSLKDQYFVELNELYNKVSIKIQQIDNQMPAQKSAEQYEKMKGFKGMLERTLHFLQVNKSNIHPGLREKIPIYERQILSILSSQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKSGMYQQLSQRNYYQQIKQGGVFPISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTPGISASPLLAEFTSADGSPANVPTQVPAKSSAAERPLDRLLKALRTTQRESLSAAVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFITHDGSGASKKMKRDTSAMPLNVSSAGSVNDSLKQSYGVGTPELQSTATSRVKWQRAEVNHALMEEIQEINQQLIDTELHVSEDDAESFTTSEGGKGTVIRCTFTAVAVCPSLKSVFASAQMSPILPLRLLVPASYPKCSPVLLDKFPDEQCRNSDDLSTKAKTKFSVLLRGLAEPMSLREIARTWDACARKVITEYAQQTGGGSFSSSYGCWESCVGAC
Length1213
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.788
Instability index71.75
Isoelectric point9.31
Molecular weight133353.68
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10030
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.30|      24|      24|     217|     240|       1
---------------------------------------------------------------------------
  217-  240 (45.71/13.28)	QPTQ..SVVRQ.QQHPQSMHQQSSLQQ
  242-  267 (38.55/ 9.64)	QPTQqpNIPLQ.QQQPQLMNQQSNLQQ
  385-  409 (37.04/ 8.88)	QPQQ..HMMSQfQSQPNQMQQQLGMQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     547.98|      77|      77|     674|     750|       3
---------------------------------------------------------------------------
   85-  137 (47.03/ 6.56)	...........MSVM.PQNTMN.NG..LAQGTP.........Q...D.MYAA...QrQMAGRQ..Q...QQ.............................QQQQahnqliyQ.Q.QKYLN...
  138-  208 (71.62/14.54)	..................QKLQQNS..LMPSHI.........Q.QQQPLLQS...T.QMQSSQ..QpMMQMssgLQPG.QTAI...P.Q...TQSMTMHSATQS.......GiQ.QNPLNSVQ
  422-  514 (51.11/ 7.89)	NNidqkqyvqAQRGLQ...EAPSTS..VDSTAQtghpgigdlQEELYQMIKSlkdQ.YFVELN..E.LYNK...VSIKiQQID...N.Q...MPAQ..KSAEQY.......E.KmKGFKGML.
  515-  575 (64.23/12.15)	ER........TLHFLQVNKSNIHPG..LRE.KI.........PIYERQIL.S......................ILSS.QRRK...PvQ...APGQQ.TFQQSS.......G.Q.APSSNI..
  576-  638 (56.07/ 9.50)	...........SQQLQT.....S.....QGL.Q.........QHDSH....T...S.QMPQASlpS.MNTG...VQTS.GAPA...P.QgtnFGVPTTQQNVTN.......A.P.QAGSN...
  639-  683 (52.28/ 8.27)	..............L...ENAQGNN..FNHVQ..............HGSMGA..................A...LQQE.RT..............GPMQGALNA.......Q.Q.QSSSNMIS
  684-  760 (135.00/35.11)	NN........AMSTMQTNNNANANS..LQQLKQ.........QRQEHQMMQS...Q.QMKQRQ..Q.MMQQ...IQQK.QTLQ...P.Q...LPIQQLKKQQQQ.......G.Q.MQFPQLHS
  761-  838 (70.64/14.22)	GN........DVNELKVRQGAAIKSgmYQQL.S.........QRNYY........Q.QIKQGG.....VFP...ISSP.QTLQtssP.Q.....ISHHSPQVDQ.hsllqsQ.V.KTGTPLHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     229.86|      58|      72|     839|     896|       4
---------------------------------------------------------------------------
  839-  896 (102.01/54.46)	AN.SP....FVPS.PSPPVAPSPMPMD.S...DKPLSNL......SSVTSAGQAGHQQTSL.APQTQSIAVNTPG
  897-  969 (63.67/31.02)	ISaSPllaeFTSAdGSPANVPTQVPAK.SsaaERPLDRLlkalrtTQRESLSAAVSDIGSV.VSMIDRIAGSAPG
  989- 1041 (64.18/31.33)	QA.RN....FITH.DGSG.ASKKMKRDtS...AMPL.NV......SSAGSVNDSLKQSYGVgTPELQSTA.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.85|      35|      78|     268|     305|       5
---------------------------------------------------------------------------
  268-  305 (53.65/26.27)	NQLMN..QQSGVVETQQQQRLPVQ.SNNLLNmQQTQQmmNQ
  345-  382 (56.20/19.61)	NARMHmlQQQKVIQQPQQQQHAQQtSMGLIQ.PQSQQ..NQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.30|      17|      18|      35|      51|       6
---------------------------------------------------------------------------
   35-   51 (28.31/13.13)	QVSNPAQS..SAIPLISQQ
   54-   72 (22.99/ 9.08)	RQSNASTSvqGSLPSLGQN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10030 with Med15 domain of Kingdom Viridiplantae
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