<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10029

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQKYLNQKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQTSAGMLLQQNNIDQKQYVQAQRGLQEAPSTSVDSTAQTGHPGIGDLQEELYQMIKSLKDQYFVELNELYNKVSIKIQQIDNQMPAQKSAEQYEKMKGFKGMLERTLHFLQVNKSNIHPGLREKIPIYERQILSILSSQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKSGMYQQLSQRNYYQQIKQGGVFPISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTPGISASPLLAEFTSADGSPANVPTQVPAKSSAAERPLDRLLKALRTTQRESLSAAVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFITHDGSGASKKMKRDTSAMPLNVSSAGSVNDSLKQSYGVGTPELQSTATSRVKWQRAEVNHALMEEIQEINQQLIDTELHVSEDDAESFTTSEGGKGTVIRCTFTAVAVCPSLKSVFASAQMSPILPLRLLVPASYPKCSPVLLDKFPDEQCRNSDDLSTKAKTKFSVLLRGLAEPMSLREIARTWDACARKVITEYAQQTGGGSFSSSYGCWESCVGAC
Length1122
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.786
Instability index72.46
Isoelectric point9.28
Molecular weight123812.35
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10029
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.82|      43|      43|     159|     201|       2
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  130-  200 (65.09/16.18)	LlhqptqsvvrqqqhpqsmhqqsslqqtqPTQQPNIPLQQQQPQLMNQQS.NLQQ.NQLMNQQSGVVETQQQQ
  201-  246 (48.22/ 9.66)	R...........................lPVQSNNLLNMQQTQQMMNQQSmSLHQpQQLANQGNMSSQNQQQQ
  288-  318 (44.51/ 8.23)	................................QQN.QLQQPQQHMMSQFQ.S.QP.NQ.MQQQLGM.....QQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     382.06|      54|      56|     634|     687|       3
---------------------------------------------------------------------------
   52-  106 (71.35/20.75)	LNQK.....L..QQNSLmpshiQQQQPLLQSTQMQSSQQ.PMMQMSSGLQP...GQTA...IP.....QTQ.S.........MT
  453-  493 (58.30/15.22)	LS.I.....LSSQRRKP.....VQAPGQQTFQQ..SS..........GQAP...SSNI...SQ.....QLQTS.........QG
  494-  539 (55.66/14.11)	LQ..........QHDSH.....TSQMPQASLPSMNTGVQ......TSGAPA...PQGTnfgVP.....TTQQN.........VT
  540-  598 (43.12/ 8.80)	NAPQ.....AG.SNL.......ENAQGN.NF......NHVQHGSM..GAALqqeRTGP...MQgalnaQQQSSsnmisnnamST
  599-  643 (60.15/16.01)	MQTNnnanaNSLQQLKQ.....QRQEHQM....MQSQ....QMKQRQ.........QM...MQ.....QIQQK.........QT
  644-  697 (93.48/30.12)	LQPQ.....LPIQQLKK.....QQQQGQMQFPQLHSGNDVNELKVRQGAAI...KSGM...YQ.....QLSQR.........NY
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.22|      15|      36|     708|     722|       4
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  708-  722 (26.02/12.58)	PISSPQTLQTSSPQI
  733-  746 (19.35/ 7.00)	SLLQSQ.VKTGTPLH
  747-  760 (20.85/ 8.24)	SANSP.FVPSPSPPV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     273.80|      86|     576|     345|     442|       5
---------------------------------------------------------------------------
  325-  411 (117.11/57.84)	.GML......LQQN..........NIDQ..KqyvqaqrglqeAPST...............................................................................................................................................................................................................................................................................................................................................SVDSTAQTGHPGIGD...LQEELYQMIK.SLKDQYFVELNEL..........YNKVSIKIQQIDNQMPAQKSAE
  420-  442 ( 7.42/ 8.24)	KGMLERTLHFLQVNK........SNIHPGlR........................................................................................................................................................................................................................................................................................................................................................................................................................................
  778-  836 (54.62/19.91)	..............................................ekipiyerqilsilssqrrkpvqapgqqtfqqssgqapssnisqqlqtsqglqqhdshtsqmpqaslpsmntgvqtsgapapqgtnfgvpttqqnvtnapqagsnlenaqgnnfnhvqhgsmgaalqqertgpmqgalnaqqqsssnmisnnamstmqtnnnananslqqlkqqrqehqmmqsqqmkqrqqmmqqiqqkqtlqpqlpiqqlkkqqqqgqmqfpqlhsgndvnelkvrqgaaiksgmyqqlsqrnyyqqikqggvfpisspqtlqtsspqishhspqvdqhsllqsqvktgtplhsanspfvpspsppvapspmpmdsdkplsnlsSVTSAGQAGHQ........QTSLAPQTQ.S......IAVNTPgisaspllaeFTSADGSPANVPTQVPAKSSAA
  837-  922 (94.66/40.23)	ERPLDRLLKALRTTQreslsaavSDI..G.............SVVS...............................................................................................................................................................................................................................................................................................................................................MIDRIAGSA.PGNGSraaVGEDLVAMTKcRLQARNFITHD............GSGASKKMKRDTSAMP......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.97|      36|     235|      13|      49|       6
---------------------------------------------------------------------------
   13-   49 (62.18/30.46)	LAQGTPQDMYAAQRQMAGRQQQQQQ..QQAHNQLIyQQQ
  249-  286 (62.79/26.75)	LGTGPNARMHMLQQQKVIQQPQQQQhaQQTSMGLI.QPQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10029 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLI
2) PISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTP
3) PLLAEFTSADGSPANVPTQVPAKSSAAERPLDRLLKALRTT
4) QKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQ
5) SQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKS
1
708
810
54
458
45
804
850
321
686










Molecular Recognition Features






MoRF SequenceStartStop




NANANA