<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10026

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDSAANWRSTQGTDPAAGGVDPNAAAPAGSDWRTQLQPEARHRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQTKTQQNPGNVQVIPNQNPPGPVSNPAQSSAIPLISQQQTRQSNASTSVQGSLPSLGQNSSSVSQASTLHNMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQKYLNQKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNL
Length353
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.02
Grand average of hydropathy-0.891
Instability index81.60
Isoelectric point9.82
Molecular weight39015.13
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10026
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.82|      22|      24|     305|     326|       1
---------------------------------------------------------------------------
  246-  264 (29.47/ 6.90)	QSTQ....MQSSQQPM.MQMSSGL
  305-  326 (42.33/13.61)	QPTQ..SVVRQQQHPQSMHQQSSL
  330-  353 (36.03/10.33)	QPTQqpNIPLQQQQPQLMNQQSNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     111.10|      19|      19|     203|     221|       2
---------------------------------------------------------------------------
  122-  140 (26.21/ 6.87)	GPVSNPAQSSAIPLISQQQ
  179-  197 (25.28/ 6.35)	NTMNNGLAQGTPQDMYAAQ
  203-  221 (34.30/11.42)	RQQQQQQQQAHNQLIYQQQ
  227-  242 (25.32/ 6.37)	KLQQNSLMPSH...IQQQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10026 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISLKMLSMESQTKTQQNPGNVQVIPNQNPPGPVSNPAQSSAIPLISQQQTRQSNASTSVQGSLPSLGQNSSSVSQASTLHNMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQ
2) MDSAANWRSTQGTDPAAGGVDPNAAAPAGSDWRTQLQPEARHRIVNKI
3) QKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNL
92
1
226
221
48
353










Molecular Recognition Features






MoRF SequenceStartStop




NANANA