<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10022

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQKYLNQKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQTSAGMLLQQNNIDQKQYVQAQRGLQEAPSTSVDSTAQTGHPGIGDLQEELYQMIKSLKDQYFVELNELYNKVSIKIQQIDNQMPAQKSAEQYEKMKGFKGMLERTLHFLQVNKSNIHPGLREKIPIYERQILSILSSQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKSGMYQQLSQRNYYQQIKQGGVFPISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTPGISASPLLAEFTSADGSPANVPTQVPAKSSAAERPLDRLLKADCWISAW
Length853
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.959
Instability index78.29
Isoelectric point9.70
Molecular weight95111.15
Publications
PubMed=19965430

Function

Annotated function 
ECO:0000256	RuleBase:RU364148
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP10022
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     122.40|      24|      24|     133|     156|       1
---------------------------------------------------------------------------
  133-  156 (47.64/11.87)	QPTQ..SVVRQ.QQHPQSMHQQSSLQQ
  158-  183 (37.43/ 7.15)	QPTQqpNIPLQ.QQQPQLMNQQSNLQQ
  294-  318 (37.33/ 7.10)	QPQQ..HMMSQfQSQPNQMQQQLGMQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.88|      29|      38|     699|     735|       5
---------------------------------------------------------------------------
  221-  249 (42.64/ 8.37)	QQ.....SMSLHQPQQL.ANQGNMSSQNQQ..QQQLL
  699-  735 (36.24/18.38)	QQikqggVFPISSPQTLqTSSPQISHHSPQvdQHSLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.25|      30|      42|       6|      44|       7
---------------------------------------------------------------------------
   25-   58 (46.45/ 6.58)	QRQMAGRQQQQQ......QQQAHNQLiyqqQKYLNQKLQQ
   59-   94 (48.81/ 8.27)	NSLMPSHIQQQQpllqstQMQSSQQP....MMQMSSGLQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     200.53|      44|     165|     319|     362|       8
---------------------------------------------------------------------------
   96-  121 (36.73/ 8.96)	......QT...AIP.......................QTQ.SMTM.......................HSAT.....QSGIQQNPLN
  319-  351 (46.23/13.34)	.....................................RLQTSAGMLLQQ............NNIDQKQYVQA.....QRGLQEAPST
  352-  407 (47.04/13.71)	SVDSTAQT...GHP....................gigDLQEE...LYQMikslkdqyfvelNELYNKVSIKI.....QQIDNQMPAQ
  454-  518 (37.62/ 9.37)	SILS.SQR...RKPvqapgqqtfqqssgqapssnisqQLQTSQG..LQQ............HDSHTSQMPQAslpsmNTGVQ....T
  519-  570 (32.90/ 7.19)	SGAPAPQGtnfGVP.........ttqqnvtnapqagsNLENAQG.................NNFNHVQHGSM.....GAALQQ....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.96|      19|      37|     610|     629|       9
---------------------------------------------------------------------------
  610-  629 (30.18/12.07)	LQQLKQQRQEHQmMQSQQMK
  650-  668 (34.78/10.65)	IQQLKKQQQQGQ.MQFPQLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.34|      31|      57|     736|     766|      11
---------------------------------------------------------------------------
  736-  766 (57.81/24.75)	QSQ.VKTGTPLHSANSP....FVPSP.SPPVAPSPMP
  767-  794 (41.50/15.83)	MDS.DK...PLSNLSSV....TSAGQ.AGHQQTSLAP
  795-  830 (36.03/12.84)	QTQsIAVNTPGISA.SPllaeFTSADgSPANVPTQVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.76|      11|      22|     576|     586|      12
---------------------------------------------------------------------------
  576-  586 (19.77/ 7.60)	MQGALNAQQQS
  599-  609 (19.99/ 7.78)	MQTNNNANANS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10022 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLI
2) PISSPQTLQTSSPQISHHSPQVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPMPMDSDKPLSNLSSVTSAGQAGHQQTSLAPQTQSIAVNTPG
3) QKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQ
4) SPLLAEFTSADGSPANVPTQVPAKSSAAER
5) SQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQIQQKQTLQPQLPIQQLKKQQQQGQMQFPQLHSGNDVNELKVRQGAAIKS
1
708
54
809
458
45
805
321
838
686










Molecular Recognition Features






MoRF SequenceStartStop




NANANA