<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10020

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDSAANWRSTQGTDPAAGGVDPNAAAPAGSDWRTQLQPEARHRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQTKTQQNPGNVQVIPNQNPPGPVSNPAQSSAIPLISQQQTRQSNASTSVQGSLPSLGQNSSSVSQASTLHNMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQKYLNQKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQTSAGMLLQQNNIDQKQYVQAQRGLQEAPSTSVDSTAQTGHPGIGDLQEELYQMIKSLKDQYFVELNELYNKVSIKIQQIDNQMPAQKSAEQYEKMKGFKGMLERTLHFLQVNKSNIHPGLREKIPIYERQILSILSSQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQI
Length810
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.982
Instability index75.18
Isoelectric point9.75
Molecular weight90462.90
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10020
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     169.96|      40|      41|     312|     351|       1
---------------------------------------------------------------------------
  304-  347 (70.25/14.32)	HQptQSvvRQQQHPQSMHQQSSLQQTQPTQQPNIPLQ.......QQQPQLM
  348-  391 (45.49/ 6.19)	NQ..QSnlQQN...QLMNQQSGVVETQ..QQQRLPVQsnnllnmQQTQQMM
  438-  472 (54.23/ 9.06)	IQ..QP..QQQQHAQ...Q.TSMGLIQPQSQQN.QLQ.......QPQQHMM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     321.90|      57|      57|     189|     245|       3
---------------------------------------------------------------------------
   21-   67 (51.45/ 8.15)	...DPNAAA...P..AGSDWR........TQlQPEARH.RIVNKIMET.....LK.KHL......PVSVPEG.L..............TEL
   83-  157 (59.36/10.63)	TSQSDYLRKislKMLSMESQT........KT.QQNPGNvQVIPNQNPP.....GPvSNPAQSSAIP.LISQQ.QtrqsnastsvqgslPSL
  189-  245 (104.90/24.94)	TPQDMYAAQ...RQMAGRQQQ........QQ.QQQAHN.QLIYQQQKY.....LN.QKLQQNSLMPSHIQQQ.Q..............PLL
  248-  303 (52.90/ 8.60)	T............QMQSSQQPmmqmssglQP.GQTA.....IPQTQSMtmhsaTQ.SGIQQNPL..NSVQQSvQ..............PLL
  770-  809 (53.29/ 8.73)	TMQTNNNA.....NANSLQQL........KQ.QRQEHQ.MMQSQQMKQ.....RQ.QMMQQ..............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.59|      14|      16|     695|     709|       4
---------------------------------------------------------------------------
  695-  709 (21.73/13.28)	APQGTNFGVpTTQQN
  730-  743 (22.86/ 9.20)	HVQHGSMGA.ALQQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.99|      20|      20|     541|     560|       7
---------------------------------------------------------------------------
  541-  560 (33.90/26.89)	EELYQMIKSLKD.....QYFVELNE
  582-  606 (29.09/21.94)	AEQYEKMKGFKGmlertLHFLQVNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.64|      25|     147|     512|     536|       9
---------------------------------------------------------------------------
  512-  536 (43.15/19.78)	QAQRGLQEAPS..........TSVDSTAQ...T.GHPGI
  614-  641 (31.74/12.44)	REKIPIYERQI..........LSILSSQRrkpV.QAPGQ
  661-  694 (22.75/ 6.67)	QTSQGLQQHDShtsqmpqaslPSMNTGVQ...TsGAP..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10020 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISLKMLSMESQTKTQQNPGNVQVIPNQNPPGPVSNPAQSSAIPLISQQQTRQSNASTSVQGSLPSLGQNSSSVSQASTLHNMSVMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQLIYQQQ
2) MDSAANWRSTQGTDPAAGGVDPNAAAPAGSDWRTQLQPEARHRIVNKI
3) QKLQQNSLMPSHIQQQQPLLQSTQMQSSQQPMMQMSSGLQPGQTAIPQTQSMTMHSATQSGIQQNPLNSVQQSVQPLLHQPTQSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQQPQLMNQQSNLQQNQLMNQQSGVVETQQQQRLPVQSNNLLNMQQTQQMMNQQSMSLHQPQQLANQGNMSSQNQQQQQLLGTGPNARMHMLQQQKVIQQPQQQQHAQQTSMGLIQPQSQQNQLQQPQQHMMSQFQSQPNQMQQQLGMQQRLQ
4) SQRRKPVQAPGQQTFQQSSGQAPSSNISQQLQTSQGLQQHDSHTSQMPQASLPSMNTGVQTSGAPAPQGTNFGVPTTQQNVTNAPQAGSNLENAQGNNFNHVQHGSMGAALQQERTGPMQGALNAQQQSSSNMISNNAMSTMQTNNNANANSLQQLKQQRQEHQMMQSQQMKQRQQMMQQI
92
1
226
630
221
48
493
810










Molecular Recognition Features






MoRF SequenceStartStop




NANANA