<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10013

Description Polymerase II transcription-mediator2
SequenceMLLGPPDFYPQTPNCPEETLTKEYAQAGYKETVEGIEEAREIVLSQIPYFCKPDAVIKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDARRKWIEALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQTRQTPNSISVAGSDNQRSNQWTKDVVEYLQHILDEFCSKEGAFVHPSFREQSSPGPTAGTNQIKMKTEASPAAGDIEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSVDVLELLLPIMLGLVDTITLSQTYVRMFVELLVRRLNDASVVDSPKGPSVSSVIAELLRYMVLAVPDTFISLDCFPLPSFVVPDVYGRGALLKITSSGGISSSKRCDAYRYLSCGYAVCSIQKRAYDLATVANPNLQARGAAKVVQALDIALVTGNLSVAYSSLFNDLSDTLMEERWIKEVSPSLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSRNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRSKSSTRVTLNNITKGSSLTDACLTAAAVDDTSGLQSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSSVAGFTRVDVLIVELIRNGIFFPQAYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDILEETRTVEEQQLYEMMSTYSSERRLVLSELSCDHSFYASGRGEYTASSCIRKQSDLPLASGGDKHGRVPEQVEDVKALLSSLLGFTYPSPVESEPRQIKTSFQESATSTLSQVETGEAKSGCEVCMRSKGQKLDDTATPFQGFSLIQSDEEDIWWVRKGTKLQESFNIEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGTSTSHVCESKMSCPHHKPNIDGDNVKDFDHTRVANLTEIGKSLKRLRLLERRSVSSWLLKTVRQLIEGNETTAAKATNSISILSLQSDDKTTSKWRLGDEELLSVLYLLDTCCDLVSCARFLVWLLAKIRGGMGSSGQPGRSSMHTRNRDHQVCQVSEALVFSSLLRYENILLAADILPDVLSALVNRNSVSAIVRHPGSTAFAYVRYFLKKYRDVAGVAKWEKSFRTTCDQRLLAELDNGRSIDGELISSSGVSAGEEIDEQVRQKLNGRSSRLVQNMKEIVQRQADEIQRSLKEKKVLATPRNPPTFEKEDSYQIAHDIVSGLVECIRQNGGANPDGDLSTVASAVSAIVANAGHVIAKHLDFAGGNYQGVNSVSNSLNFVRHTLRVHINSLCLLKETLGDRFSRAFEIALAVETSGAVTAAFASPKMHRNQFQPSPEAHDAYGNHTSDLSNSGKGFVGRTAKVSAAVSALVVGAVVHGAVSLERMVAALKIKDGLDILQLLRGLKSSSNGVSRPTGTFRIEHSTDVLVHWFRVLLGNCRTVYDGLIADILGDSYILALSRLQQMLPLSVIFPPAYSIFAMVLWRRYIFNREDPQLYQSLSNAISDITRHQPFREICFRNTHRLYNLLASDVGDSEFAAMLETHSPDRNSKILPFIPLRARLFLDALIDCNTPTIQGDGASEPCDPKDNELKLSERLMQLLDTLQPAKFHWQWVEMRLLLDEQALMEKVAAGKTALESLRSLSPKAEGFTLSDSEKGFTEVILSRLLARPDAAPLYSEAVRLLGKLQESLVMDVKWILQGQDAILGRRSTRQQLVHIAQRKGLSTKAQVWKPWGWSSLLSDVIPNKTAKRKLEVTSIEEGEVVDDTVDAKRPSKTPPHSVDRSFEAIRSINKYLTEKALAELVLPCIDRSSADIRGILSVDLIKQMGTISEHIKAIARNGAKQAGSVPSGNEVPSSKSSGRKGIRGGSPNIGRRAPVGNDPSPPSASALRAALWLRLQFIIRLLPVIMADRSMRQTLASAILGLLATRMIYEDADLPLPPTNATALRREVDSLLEPPLDVLLDRPGESLFERLLCVLHALLGSYKPSWLKSRSASRSTIRIQRDFSAFDNEAAEGLQSALDHMELPETIRRRIQAAMPLLPPSRHPSLQCQPPQLSLAALTPLQSSTSGVGPQQKSCSASWVPTNVSGRSKAALPSHDPEMEVDPWNLLEDGTSCPSTASGSHGASGVTGDHANLKACSWLKGAVRVRRTELTYIGSLDDDT
Length2145
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.256
Instability index50.69
Isoelectric point8.47
Molecular weight237494.33
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10013
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.15|      27|      50|     287|     336|       1
---------------------------------------------------------------------------
  287-  313 (46.19/60.83)	VL.ELLLPIMLGLVDT.ITLSQTYVRMFV
  337-  365 (39.96/12.95)	VIaELLRYMVLAVPDTfISLDCFPLPSFV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.19|      27|      50|    2025|    2052|       2
---------------------------------------------------------------------------
 2025- 2052 (46.08/35.98)	PSRHPSLQCQPPQLsLAALTPLQSSTSG
 2078- 2104 (53.11/36.85)	PSHDPEMEVDPWNL.LEDGTSCPSTASG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.08|      45|      48|     126|     170|       5
---------------------------------------------------------------------------
  126-  170 (76.94/53.93)	SLSEHVPHGYRRKSLFEGLIRYNVPLL.....RATWFIKVTYLNQTRQTP
  172-  221 (66.14/45.16)	SISVAGSDNQRSNQWTKDVVEYLQHILdefcsKEGAFVHPSFREQSSPGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.99|      10|      49|     938|     947|       9
---------------------------------------------------------------------------
  938-  947 (18.30/ 9.58)	WLLKTVRQLI
  988-  997 (18.69/ 9.95)	YLLDTCCDLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     154.06|      45|     368|    1049|    1093|      14
---------------------------------------------------------------------------
 1040- 1077 (53.57/44.28)	.......ALVFSSLLRYENILLAADIL....PD....VLSALVNRNSVSAIVR
 1078- 1097 (22.80/12.79)	HPGSTAFAYVRYFLKKYRDV.................................
 1426- 1455 (25.49/15.55)	................YDG..LIADIL....GDsyilALSRLQQMLPLS.VIF
 1456- 1492 (52.19/42.87)	PPAYSIFAMV..........LWRRYIFnredPQ....LYQSL..SNAISDITR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10013 with Med12 domain of Kingdom Viridiplantae
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