<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP10012

Description Polymerase II transcription-mediator2
SequenceMHRYSSNSAGFSGGRDGARLEASPFSSSSSGYPVSSRRQQQLVPYKLKCDKDPLNNKLGPPDFYPQTPNCPEETLTKEYAQAGYKETVEGIEEAREIVLSQIPYFCKPDAVIKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDARRKWIEALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQTRQTPNSISVAGSDNQRSNQWTKDVVEYLQHILDEFCSKEGAFVHPSFREQSSPGPTAGTNQIKMKTEASPAAGDIEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSVDVLELLLPIMLGLVDTITLSQTYVRMFVELLVRRLNDASVVDSPKGPSVSSVIAELLRYMVLAVPDTFISLDCFPLPSFVVPDVYGRGALLKITSSGGISSSKRCDAYRYLSCGYAVCSIQKRAYDLATVANPNLQARGAAKVVQALDIALVTGNLSVAYSSLFNDLSDTLMEERWIKEVSPSLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSRNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRSKSSTRVTLNNITKGSSLTDACLTAAAVDDTSGLQSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSSVAGFTRVDVLIVELIRNGIFFPQAYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDILEETRTVEEQQLYEMMSTYSSERRLVLSELSCDHSFYASGRGEYTASSCIRKQSDLPLASGGDKHGRVPEQVEDVKALLSSLLGFTYPSPVESEPRQIKTSFQESATSTLSQVETGEAKSGCEVCMRSKGQKLDDTATPFQGFSLIQSDEEDIWWVRKGTKLQESFNIEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGTSTSHVCESKMSCPHHKPNIDGDNVKDFDHTRVANLTEIGKSLKRLRLLERRSVSSWLLKTVRQLIEGNETTAAKATNSISILSLQSDDKTTSKWRLGDEELLSVLYLLDTCCDLVSCARFLVWLLAKIRGGMGSSGQPGRSSMHTRNRDHQVCQVSEALVFSSLLRYENILLAADILPDVLSALVNRNSVSAIVRHPGSTAFAYVRYFLKKYRDVAGVAKWEKSFRTTCDQRLLAELDNGRSIDGELISSSGVSAGEEIDEQVRQKLNGRSSRLVQNMKEIVQRQADEIQRSLKEKKVLATPRNPPTFEKEDSYQIAHDIVSGLVECIRQNGGANPDGDLSTVASAVSAIVANAGHVIAKHLDFAGGNYQGVNSVSNSLNFVRHTLRVHINSLCLLKETLGDRFSRAFEIALAVETSGAVTAAFASPKMHRNQFQPSPEAHDAYGNHTSDLSNSGKGFVGRTAKVSAAVSALVVGAVVHGAVSLERMVAALKIKDGLDILQLLRGLKSSSNGVSRPTGTFRIEHSTDVLVHWFRVLLGNCRTVYDGLIADILGDSYILALSRLQQMLPLSVIFPPAYSIFAMVLWRRYIFNREDPQLYQSLSNAISDITRHQPFREICFRNTHRLYNLLASDVGDSEFAAMLETHSPDRNSKILPFIPLRARLFLDALIDCNTPTIQGDGASEPCDPKDNELKLSERLMQLLDTLQPAKFHWQWVEMRLLLDEQALMEKVAAGKTALESLRSLSPKAEGFTLSDSEKGFTEVILSRLLARPDAAPLYSEAVRLLGKLQESLVMDVKWILQGQDAILGRRSTRQQLVHIAQRKGLSTKAQVWKPWGWSSLLSDVIPNKTAKRKLEVTSIEEGEVVDDTVDAKRPSKTPPHSVDRSFEAIRSINKYLTEKALAELVLPCIDRSSADIRGILSVDLIKQMGTISEHIKAIARNGAKQAGSVPSGNEVPSSKSSGRKGIRGGSPNIGRRAPVGNDPSPPSASALRAALWLRLQFIIRLLPVIMADRSMRQTLASAILGLLATRMIYEDADLPLPPTNATALRREVDSLLEPPLDVLLDRPGESLFERLLCVLHALLGSYKPSWLKSRSASRSTIRIQRDFSAFDNEAAEGLQSALDHMELPETIRRRIQAAMPLLPPSRHPSLQCQPPQLSLAALTPLQSSTSGVGPQQKSCSASWVPTNVSGRSKAALPSHDPEMEVDPWNLLEDGTSCPSTASGSHGASGVTGDHANLKACSWLKGAVRVRRTELTYIGSLDDDT
Length2200
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.279
Instability index51.57
Isoelectric point8.63
Molecular weight243482.78
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP10012
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.15|      27|      50|     342|     391|       1
---------------------------------------------------------------------------
  342-  368 (46.19/59.58)	VL.ELLLPIMLGLVDT.ITLSQTYVRMFV
  392-  420 (39.96/12.48)	VIaELLRYMVLAVPDTfISLDCFPLPSFV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.19|      27|      50|    2080|    2107|       2
---------------------------------------------------------------------------
 2080- 2107 (46.08/25.28)	PSRHPSLQCQPPQLsLAALTPLQSSTSG
 2133- 2159 (53.11/25.89)	PSHDPEMEVDPWNL.LEDGTSCPSTASG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     261.88|      89|     372|    1052|    1148|       9
---------------------------------------------------------------------------
 1052- 1148 (139.59/97.62)	VSCARFLVWLLAK........IRGGMGSSGQPGRSSMHTRNrDHQvcqvSEALV..FSSLL...R..YENilLAADILPD....VLSALVNRNSVSaIVRHPGSTAFAYV...RYFLKK
 1419- 1529 (122.29/66.75)	VSLERMVAALKIKdgldilqlLRGLKSSSNGVSRPTGTFRI.EHS....TDVLVhwFRVLLgncRtvYDG..LIADILGDsyilALSRLQQMLPLS.VIFPPAYSIFAMVlwrRYIFNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.48|      35|      49|     172|     220|      10
---------------------------------------------------------------------------
  120-  168 (41.15/25.33)	KRLRAINESRAQKRKAGQVYgvplSGslLIKPGVypeqrPCnedARRKW
  177-  211 (63.33/46.24)	KRLRSLSEHVPHGYRRKSLF....EG..LIRYNV.....PL...LRATW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP10012 with Med12 domain of Kingdom Viridiplantae
Unable to open file!