<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09963

Description Pre-mRNA-processing protein 40A
SequenceMASNMQSSGLPQPPRPPMMGSSAQPQNLGPPMPMQFRPVMPSQHPPQFMPPAAQQFRPVGEPMAGANVGMPGQMPHFPQPGQHLPHSNQVPPVSQGVPMVYQPARPMSSAPMQQQQQTAYAGGHLPTMGAPMQPLTYTYQPTSIPPVAQPWSTGPGQSVHHVPPLVPSGHQPVSAPTTLPPVNLSEPSSSDWQEHTAAEGKKYYYNKKTRQSSWEKPVELMTPLERADASTEWKEFTTPEGRKYYFNKVTKQSKWTIPDELKVARELAENASNQQPDRESGIATSALVRSAAFEPSTAPANQSSSAVGIIASSAHDGSSNSVLSGPPLPHNVENTSSSIVGMQNGGSSTAVVPVAASTEVPLVATDAGSSRNNDENSSLTTGADAEDGTSAEDLVEAKKTMPVAGKINVTPVEEKTSEEEPVVYATKMEAKNAFKSLLESVNVESDWTWDQTMRVIINDKRYGALKTLGERKQAFNEYLNQRKKFEAEEKRIKQRKARDDFLAMLEESKELTSSTRWSKAILMFEDDERFKAVERPREREDLFENYLVELHKKEKAKAAEEHKRYVAEYRAFLESCDFIKASTQWRKVQERLEDDERYSRLEKFDRLDIFQEYIRHLEKEEEEQKRVQKDQVRRQERKNRDGFRKMLEEHVADGTLNARTRWRDYCAQIKDSQSYLAVASNTSGSTPKELFDDVIEELGKQYQEDKIQIKEVVKSGKIPMTTSWTLEEFQTATLEDDALKGISTINIKLVYDDQLERLKEKEQKDAKKRQRLGENFSDLLYSIKEISASSTWDDSKQLFEDSQEFRALDSETYARELFEECVVHLKERLKEKERLREEEKAKREKEREEKEKKKEKERKEKERKEKERDHREEREKEKGKDRSRRDEMEFDGADLNTHGAKDKKRDKDKEKKHKRRHHDTDDVSSERDDKDDAKKSRRHSSDRKKSRKHAHGSDSDSENRHKRHKKDRDSSRRNGAHELEDGELGEDGEIY
Length991
PositionUnknown
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-1.153
Instability index54.51
Isoelectric point6.27
Molecular weight113293.75
Publications









Function






Annotated function


GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09963
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     163.97|      27|      27|     830|     856|       1
---------------------------------------------------------------------------
  590-  619 (24.44/ 9.45)	ERL.........EDDERYSRLEKFDRldifQEYIRH.......lEK
  620-  640 (22.34/ 7.91)	E............EEEQKRVQKDQVR....RQERKNR.........
  833-  861 (35.18/17.32)	ERL.........REEEKAKREKEREE....KEKKKEK...erK.EK
  862-  885 (37.15/18.76)	ER..........KEKERDHRE.ERE.....KEKGKDR.....S.RR
  886-  926 (21.29/ 7.14)	DEMefdgadlntHGAKDKKRDKDKEK....KHKRRHHdtddvS.SE
  927-  948 (23.57/ 8.81)	RDD.........KDDAKKSRRHSSDR....KKSRK...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     397.63|      66|      66|     414|     479|       2
---------------------------------------------------------------------------
  414-  479 (95.17/57.75)	EKTSEEEPVVY.ATKMEAKNAFKSLL.ES.V....N.VESDWTW.....DQTMRVIINDKRYGAL......KTLGERKQAFNE...YL
  483-  547 (93.15/56.36)	KKFEAEEKRIK.QRK..ARDDFLAMLeES.K....E.LTSSTRW.....SKAILMFEDDERFKAV......ERPREREDLFEN...YL
  555-  585 (26.09/10.24)	KAKAAEEHKRY.VAE......YRAFL.ES.C....DfIKASTQW............................................
  641-  695 (47.04/24.65)	...................DGFRKML.EE.HvadgT.LNARTRW.....RDYCAQIKDSQSYLAVasntsgSTPKE...LFDD...VI
  696-  755 (54.49/29.77)	....EELGKQYqEDKIQIKE....VV.KS.G....K.IPMTTSWtleefQTATL...EDDALKGI......STI.NIKLVYDD...QL
  756-  825 (81.70/48.48)	ERLKEKEQKDA.KKRQRLGENFSDLL.YSiK....E.ISASSTW.....DDSKQLFEDSQEFRAL......DSETYARELFEEcvvHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     262.95|      39|      39|     181|     219|       3
---------------------------------------------------------------------------
   25-   62 (31.28/ 9.71)	PQNL......gpP.MPMqfrpvmpS.....Q...HPPQF.....MPPAAQQ..FRPVGE...P........
   92-  133 (37.60/12.94)	PVSQgvpmvyqpA.RPM.......S.....SapmQQQQQ.....TAYAG........GH...LPTMGAPMQ
  134-  174 (45.27/16.86)	PLTY........TyQPT.......SippvaQ...PW........STGPGQSVHHVPPLV...PSG.HQPVS
  181-  219 (63.56/26.20)	PVNL........S.EPS.......S.....S...DWQEH.....TAAEGKKYYYNKKTR...QSSWEKPVE
  223-  260 (60.82/24.80)	PLER........A.D.A.......S.....T...EWKEF.....TTPEGRKYYFNKVTK...QSKWTIPDE
  264-  304 (24.41/ 6.20)	AREL........A.ENA.......S.....N...QQPDResgiaTSALVRSAAFEPSTApanQSS......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.21|      23|      27|     310|     333|       4
---------------------------------------------------------------------------
  320-  348 (30.75/23.53)	NSVL.SGpPLPHNVEntsssIVGMQNGGSS
  349-  370 (19.54/ 8.65)	TAV....vPVAASTE..vplVATDA..GSS
  376-  390 (19.92/ 8.97)	NSSLtTG...............ADAEDGTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.06|      12|      59|       9|      20|       5
---------------------------------------------------------------------------
    9-   20 (28.15/13.10)	GLP.QPPRPPMMG
   69-   81 (23.91/10.11)	GMPgQMPHFPQPG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09963 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ERLREEEKAKREKEREEKEKKKEKERKEKERKEKERDHREEREKEKGKDRSRRDEMEFDGADLNTHGAKDKKRDKDKEKKHKRRHHDTDDVSSERDDKDDAKKSRRHSSDRKKSRKHAHGSDSDSENRHKRHKKDRDSSRRNGAHELEDGELGEDGEIY
2) IPDELKVARELAENASNQQPDRESGIATSALVRSAAFEPSTAPANQSSSAVGIIASSAHDGSSNSVLSGPPLPHNVENTSSSIVGMQNGGSSTAVVPVAASTEVPLVATDAGSSRNNDENSSLTTGADAEDGTSAEDLVEAKKTMPVAGKINVTPVEEKTSEEEPVVYA
3) MASNMQSSGLPQPPRPPMMGSSAQPQNLGPPMPMQFRPVMPSQHPPQFMPPAAQQFRPVGEPMAGANVGMPGQMPHFPQPGQHLPHSNQVPPVSQGVPMVYQPARPMSSAPMQQQQQTAYAGGHLPTMGAPMQPLTYTYQPTSIPPVAQPWSTGPGQSVHHVPPLVPSGHQPVSAPTTLPPVNLSEPSSSDWQEHTAAEGKKYYYN
833
257
1
991
425
206










Molecular Recognition Features






MoRF SequenceStartStop




1) KKHKRRHH
2) RHKRHKKDR
911
960
918
968