<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09893

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMNVQLYMQNLDRIKCRLLEGTNAQDVRALVLDMQARLLLDMLGKGIESALTNPSTLLPEPWQASSDMLSSIDADKMTVEPALLPNIQGYVDAVLDLASHFITRLRRYASFCRTLASHVGPSSTTGTSRNMVTSPTNSSPSPSNNQGNQGGSTSATGNSQMQEWVQGAIAKISNNSDGAATATQNPMSTRTSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCLLFRRRQSPRLLASSQKNQDSAMQKIQHMMNAKTEDNSSTVRSGLGAAKVEEGHSARGGQFVLGGAKGPEENPIGKSVRIGSGNAGQGYTSDEVKVLFLILVDLCRRTSTLPHPLPASQVGSSSIIIRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELQPPAEEWHRRNMFGGPWSEPDDFGPLDNMPRLKISGSINSHLSDMEVDAVSSIGIDLWPRKRRLSERDAAFGLKTSVGLGGYLGVMGSRRDVVTAVWRTGLDGDWYKCIRCLRQTCAFAHPGAPNQTNEREAWWISRWSHACPMCGGSWVKVV
Length552
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.298
Instability index42.77
Isoelectric point8.72
Molecular weight60163.79
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09893
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     316.31|      99|     113|      76|     187|       1
---------------------------------------------------------------------------
   79-  143 (97.40/60.11)	...............................................EPALLP...NIQ.GY..V.DAV.LDLASHFITRLRRYASFC.........RTL.A.SHVGPSSTTGTSRNMVTSPT..NSSPSPSN
  144-  271 (133.04/98.77)	NQGN..QGGSTSATGNSQMQEWVQGAIAKISNNSDGaatatqnpmstRTSFMPisiNTG.TFpgT.PAVrLIGDCHFLHRLCQLLLFCllfrrrqspRLL.AsSQKNQDSAMQKIQHMMNAKTedNSSTVRSG
  278-  351 (85.87/51.19)	EEGHsaRGGQFVLGGAKGPEENPIGKSVRIGSGNAG.......................qGY..TsDEV.KVLFLILVDLCRRTSTLP.........HPLpA.SQVGSSS.......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.43|       9|      45|     374|     383|       2
---------------------------------------------------------------------------
  374-  383 (16.07/13.76)	LGPhMQNMPR
  422-  430 (20.36/11.43)	FGP.LDNMPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.54|      40|      44|     431|     470|       3
---------------------------------------------------------------------------
  431-  470 (69.33/49.27)	LKISGSINSHLSDM..EVDAVSSI...GID.LWPRKRRLSERDAAF
  472-  517 (57.21/39.35)	LKTSVGLGGYLGVMgsRRDVVTAVwrtGLDgDWYKCIRCLRQTCAF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09893 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLASSQKNQDSAMQKIQHMMNAKTEDNSSTVRSGLGAAK
2) SSTTGTSRNMVTSPTNSSPSPSNNQGNQGGSTSATGNSQ
238
121
276
159










Molecular Recognition Features






MoRF SequenceStartStop




NANANA