<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09884

Description Putative mediator of RNA polymerase II transcription subunit 19b
SequenceMISFGISGPRELSGAVDLISRYKLLNHHSFFCKKPLPLAISDTNYLNNVVGDTEIRKGEGMELDQLFQNSCSSEKTAYIQPFDMETLGQAFQLRETAPVDLPSAEKGTPTISGKSKVKSKDKVKKHKKHKEKDRDKEKEQKKHKHRHKDRSKDKDKDKDKDKEKKKDKSGNHDLGGDHSKKHEKKRKQEVTGSSANVQNHKKTQKHKIQ
Length209
PositionHead
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.04
Grand average of hydropathy-1.412
Instability index24.62
Isoelectric point9.71
Molecular weight23907.83
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
transcription factor binding	GO:0008134	IBA:GO_Central
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP09884
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.89|      21|      21|     129|     149|       1
---------------------------------------------------------------------------
  129-  149 (39.77/12.68)	HKEKDRDKEKEQKKHKHRHKD
  153-  173 (34.12/10.13)	DKDKDKDKDKEKKKDKSGNHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.58|      11|      20|     180|     190|       2
---------------------------------------------------------------------------
  180-  190 (17.63/ 9.52)	KKHEKKRKQEV
  198-  208 (18.96/10.85)	QNHKKTQKHKI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP09884 with Med19 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) QAFQLRETAPVDLPSAEKGTPTISGKSKVKSKDKVKKHKKHKEKDRDKEKEQKKHKHRHKDRSKDKDKDKDKDKEKKKDKSGNHDLGGDHSKKHEKKRKQEVTGSSANVQNHKKTQKHKIQ
89
209

Molecular Recognition Features

MoRF SequenceStartStop
1) HKKTQKHKIQ
2) KDKVKKHKKHKEKDRDKEKEQKKHKHRHKDRSKDKDKDKDKDKEKKKDKSGNHDLGGDHSKKHEKKRKQEVT
200
120
209
191