<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09881

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNL
Length358
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.02
Grand average of hydropathy-0.848
Instability index76.31
Isoelectric point10.04
Molecular weight39388.77
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09881
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.75|      24|      25|     175|     198|       1
---------------------------------------------------------------------------
  187-  210 (35.32/ 9.78)	NGLAQGTPQDMYAAQRQMAGRQQQ
  211-  230 (32.58/ 8.36)	QQQQQAHNQFMY....QQQKLLMN
  231-  247 (28.85/ 6.42)	QKLQQ..NS..RMQPH.IQQQ..Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     125.42|      25|      26|     305|     329|       2
---------------------------------------------------------------------------
  111-  146 (27.03/ 6.82)	QNP..GNAqVIPNQNPPGPGSNpaqssaiplmS..QQQTR
  270-  293 (32.17/ 9.94)	QPG..QIA.IPQT...QSMAMQ..........SatQSGIQ
  310-  333 (38.75/13.94)	QPT..PSV.VRQQQHPQSMHQQ..........SslQ...Q
  335-  356 (27.47/ 7.09)	QPTqqPNI.PLQQQPQQLMGHQ..........S.......
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09881 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNL
2) MDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKI
96
1
358
52










Molecular Recognition Features






MoRF SequenceStartStop




1) KISLKML
2) MDGAANWR
95
1
101
8