<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09879

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKAVKIPC
Length1036
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.859
Instability index68.96
Isoelectric point9.79
Molecular weight114347.76
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09879
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     335.70|      43|      43|     335|     377|       2
---------------------------------------------------------------------------
  180-  225 (40.23/ 7.25)	MPQN.TMNNGLAQgTPQdmyaaqrQMAGRQQ.QQQQQQAHNQ.....FMYQ.QQ
  231-  259 (38.18/ 6.31)	QKLQ.Q.NSRMQP.HIQ.......Q...QQT.LLQSTQ..........MQS.SQ
  335-  377 (84.18/27.47)	QPTQ.QPNIPLQQ.QPQ.......QLMGHQS.NLQQNQLVNQQSGAVEMQQ.QQ
  379-  421 (46.78/10.26)	LPVQ.STNLLNMH.QTQ.......QMMNQQSmPLHQPQQLANQ.GNVSSLN.QQ
  483-  524 (41.06/ 7.63)	QPNQtQQQLGMQQ.RLQ.......TSAGML...LQQNN.IDQQKQYVQAQKvLQ
  715-  754 (42.09/ 8.10)	VPTT.QQNV..TN.APQ.......A.ASNPE.NAQGNNFNPVQHGSMGTAL.QQ
  813-  854 (43.19/ 8.61)	QMKQ.RQQM.LQQmQQK.......KILQQQL.PIQQLQ.KQQQQGPIQVQQ.LH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     123.16|      26|      33|     105|     130|       4
---------------------------------------------------------------------------
  105-  130 (48.41/18.64)	SQKKTQQNPGNAQV......IPNQNPPGPGSN
  141-  164 (40.38/13.93)	SQQQTRQ.P.NAST......SVQGSLPSVGQN
  662-  693 (34.37/10.39)	MSQQHQTSQGLQQHdshtnqMPQASLPSMNTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.80|      13|      20|     760|     773|       7
---------------------------------------------------------------------------
  760-  773 (20.03/12.79)	MQGALNAQhQSNSN
  783-  795 (23.77/10.13)	MQTNTNAM.QANVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.96|      30|      37|     879|     914|       8
---------------------------------------------------------------------------
  875-  906 (52.77/34.49)	YQPLNQRNYYQ.QIKRG................DVFPisSPQNLQASSP
  911-  957 (41.19/14.40)	YSHVDQHSLLQsQVKTGtplhsanspfvpspspPVAP..SPVPLDSDKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.00|      19|      39|     539|     557|       9
---------------------------------------------------------------------------
  539-  557 (29.64/16.92)	HPGTGDSQEELYQMIKSLK
  561-  579 (25.70/13.62)	FAELNDVYNKISMKIQNID
  580-  598 (28.66/16.10)	NHMPAQKSAEQYERLKGFK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     117.41|      23|      38|     270|     292|      10
---------------------------------------------------------------------------
  267-  289 (41.87/17.42)	SGL.................Q.PG...QIAIPQ...TQSMA.MQSATQ
  290-  332 (24.98/ 6.81)	SGIqqnalnsvqqpvqsllqQ.PT...PSVVRQqqhPQSMH.QQSSLQ
  613-  639 (25.91/ 7.39)	SSI.................Q.PGfreKISIFE...RQILSiMSSQRR
  640-  656 (24.65/ 6.60)	KPV.................QaPG...QQTF...........QQSGGQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09879 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLL
2) MDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKI
3) MSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQK
4) PISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSI
5) QQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMY
96
1
634
894
831
505
52
827
984
875










Molecular Recognition Features






MoRF SequenceStartStop




1) RPLDRLLKAVKIPC
1023
1036