<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09877

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKAINLHNILS
Length1039
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.857
Instability index69.84
Isoelectric point9.80
Molecular weight114712.10
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09877
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     724.16|      79|      79|     244|     322|       2
---------------------------------------------------------------------------
   43-  113 (50.63/ 7.59)	E..AR..QRI.VNKI....METLKKhlP.VSVPEG..L.TElHK.IAVRF.......EEKIY...TAATSQS.....DYLRKI........SLKMLSME.SQK.....KTQQNP
  114-  165 (65.20/13.01)	G..NA..QVI...........PNQN..P...PGPG..S.NP.AQsSAIP................LMSQQQTR..QPNASTSV........QG...SL......PSV...GQNL
  169-  243 (79.71/18.41)	S..QT..LTL.QNLS...GM.......PQNTMNNG..L.AQ.GT....PQ.......DMYAAqrqMAGRQQQQ.QQQQAHNQF........MYQQQKLLmNQKLQQNSRMQPHI
  244-  322 (142.78/41.88)	Q..QQ..QTL.LQST...QMQSSQQ..PMVQMSSG..L.QP.GQ.IAIPQ.......TQSMA...MQSATQSG.IQQNALNSV........QQPVQSLL.QQPTPSVVRQQQHP
  323-  370 (62.98/12.19)	QsmHQ..QSS.LQQT.....QPTQQ..PNIPLQQ.....QP.QQ.L..M...................GHQSN.LQQN.............Q.....L.........VNQQSGA
  374-  452 (76.97/17.39)	Q..QQ..QRLpVQSTnllNMHQTQQ..MMNQQSMP..LhQP.QQ.LA.NQ.......GN......VSSLNQQ...QQQLLGTVpnvrmhmlQQ..QKPI.QQP.....QQQQHA
  576-  646 (58.85/10.65)	Q..NI..DNH.M.PA...QKSAEQY..ERLKGFKG..M.LE.RI.LHFLQ...........A...NKSSIQPG.FREK.ISIF........ERQILSIM.SSQRRKPV..QAPG
  647-  689 (53.61/ 8.70)	Q..Q....TF.QQS.......GGQA..PSSNMSQ................................QHQTSQG.LQQHDSHTN........QMPQASL....PS..........
  808-  870 (62.53/12.02)	.........M.MQNQ...QMKQRQQ..MLQQMQQKkiL.QQ..Q.LPIQQ...............LQKQQQQGpIQVQQLHSG........ND.VNE.L.K......VRQGAAI
  871-  957 (70.90/15.13)	K..SGmyQPL.NQRN...YYQQIKR..GDVFPISS..P.QN.LQ.ASSPQishyshvDQHSL...LQSQVKTG.TPLHSANSP........FVPSPSPP.VAPSP.VPLDSDKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.04|      15|      15|     707|     721|       3
---------------------------------------------------------------------------
  707-  721 (29.14/11.78)	APQASNFGVPTTQQN
  772-  786 (20.90/ 6.24)	SNMISNNAMSTMQTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.66|      28|      37|     961|     989|       5
---------------------------------------------------------------------------
  499-  531 (34.73/14.50)	TSA..GmllqqNNIDQQKQYVQ.AQKVLQEAP.......STSV
  965- 1000 (36.08/19.44)	TSA..G.....QAGHQQTSLAPlTQSIAVNTPgisasplLAEF
 1001- 1028 (35.86/15.24)	TSAdgG.....QVS..VPTQVP.TKSSAAERP.......LDRL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09877 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLL
2) MDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKI
3) MSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQK
4) PISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSI
5) QQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMY
96
1
634
894
831
505
52
827
984
875










Molecular Recognition Features






MoRF SequenceStartStop




1) NLHNIL
1033
1038