<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09876

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKALNVINMLINLHNILS
Length1046
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.840
Instability index69.44
Isoelectric point9.80
Molecular weight115510.10
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09876
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     673.53|      79|      79|     244|     322|       2
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  114-  165 (65.20/ 9.44)	G..NA..QVI...........PNQNP...PGPG..S.NPAQsSAIP................LMSQQQTR..QPNASTSV........QG...SL......PSV...GQNL
  169-  243 (79.71/13.40)	S..QT..LTL.QNLS...GM.....PQNTMNNG..L.AQGT....PQ.......DMYAAqrqMAGRQQQQ.QQQQAHNQF........MYQQQKLLmNQKLQQNSRMQPHI
  244-  322 (142.78/30.64)	Q..QQ..QTL.LQST...QMQSSQQPMVQMSSG..L.QPGQ.IAIPQ.......TQSMA...MQSATQSG.IQQNALNSV........QQPVQSLL.QQPTPSVVRQQQHP
  323-  370 (62.98/ 8.83)	QsmHQ..QSS.LQQT.....QPTQQPNIPLQQ.....QPQQ.L..M...................GHQSN.LQQN.............Q.....L.........VNQQSGA
  374-  452 (76.97/12.65)	Q..QQ..QRLpVQSTnllNMHQTQQMMNQQSMP..LhQPQQ.LA.NQ.......GN......VSSLNQQ...QQQLLGTVpnvrmhmlQQ..QKPI.QQP.....QQQQHA
  576-  646 (58.85/ 7.70)	Q..NI..DNH.M.PA...QKSAEQYERLKGFKG..M.LERI.LHFLQ...........A...NKSSIQPG.FREK.ISIF........ERQILSIM.SSQRRKPV..QAPG
  647-  689 (53.61/ 6.27)	Q..Q....TF.QQS.......GGQAPSSNMSQ...............................QHQTSQG.LQQHDSHTN........QMPQASL....PS..........
  808-  870 (62.53/ 8.71)	.........M.MQNQ...QMKQRQQMLQQMQQKkiL.QQ.Q.LPIQQ...............LQKQQQQGpIQVQQLHSG........ND.VNE.L.K......VRQGAAI
  871-  957 (70.90/10.99)	K..SGmyQPL.NQRN...YYQQIKRGDVFPISS..P.QNLQ.ASSPQishyshvDQHSL...LQSQVKTG.TPLHSANSP........FVPSPSPP.VAPSP.VPLDSDKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.93|      15|      15|     707|     721|       3
---------------------------------------------------------------------------
  707-  721 (29.15/14.22)	APQASNFGVPTTQQN
  725-  738 (20.15/ 6.93)	APQAAS.NPENAQGN
  772-  786 (20.63/ 7.32)	SNMISNNAMSTMQTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.11|      14|      15|     494|     507|       4
---------------------------------------------------------------------------
  494-  507 (25.55/ 9.00)	QQRLQTSAGMLLQQ
  512-  525 (21.56/ 6.40)	QQKQYVQAQKVLQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.47|      26|      35|     961|     989|       5
---------------------------------------------------------------------------
  968- 1003 (28.23/24.43)	GQAGhqQTSLAPlTQSIAVNTPgisasplLAEFTSA
 1006- 1031 (43.25/24.43)	GQVS..VPTQVP.TKSSAAERP.......LDRLLKA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09876 with Med15 domain of Kingdom Viridiplantae
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