<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09875

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKALEHGFERY
Length819
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.901
Instability index72.88
Isoelectric point9.71
Molecular weight91078.84
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09875
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     141.68|      38|      39|      81|     119|       2
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   68-  111 (60.88/12.67)	TQS.GIQQnalnsvQQPVQSLLQQPTPSVVRQQQHPQSMHQQS..SL
  431-  470 (43.78/ 6.67)	QQS.GGQA......PSSNMSQQHQTSQGLQQHDSHTNQMPQASlpSM
  578-  610 (37.01/ 6.15)	QQLkQHQE......HQMMQN..QQ....MKQRQQMLQQMQQKK..IL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.10|      38|      39|     665|     702|       4
---------------------------------------------------------------------------
  173-  206 (50.59/10.97)	QQMMNQQSMPLHQPQQL.ANQGNV.SSLNQ.QQQQLL..
  263-  299 (47.29/ 9.68)	QPNQTQQQLGM..QQRLQTSAGMLlQQNNIDQQKQYVQA
  665-  702 (60.22/14.70)	QQIKRGDVFPISSPQNLQASSPQI.SHYSHVDQHSLLQS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.94|      20|      86|     532|     551|       5
---------------------------------------------------------------------------
   48-   66 (29.69/ 8.07)	GLQPGQIAIPQTQSMAM.QS
  215-  230 (28.00/ 7.03)	HMLQQQK.PIQ...QPQQQQ
  532-  550 (30.24/ 8.40)	.LQQGSTGPMQGALNAQHQS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      53.44|      15|      19|     473|     490|       6
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  473-  486 ( 9.97/10.25)	.......GVPTSGaPgiQHVP
  487-  503 (21.20/ 7.95)	APQAsnfGVPTTQ....QNVT
  720-  731 (22.27/ 8.78)	SPSP...PVAPS..P....VP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.00|      19|      41|     319|     337|       7
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  319-  337 (29.64/18.63)	HPGTGDSQEELYQMIKSLK
  341-  359 (25.70/15.01)	FAELNDVYNKISMKIQNID
  360-  378 (28.66/17.73)	NHMPAQKSAEQYERLKGFK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.94|      22|     454|     145|     166|       9
---------------------------------------------------------------------------
   25-   45 (28.13/ 6.83)	QQQTL.LQSTQMQSSQQPmVQM.
  407-  425 (28.54/ 7.06)	ERQILSIMSSQRRK...P.VQAP
  611-  631 (34.27/10.20)	.QQQLPIQQLQKQQQQGP.IQVQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.28|      15|      15|     139|     153|      10
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  139-  153 (25.44/ 9.78)	QQNQLVNQQSGAVEM
  155-  169 (25.84/10.05)	QQQRLPVQSTNLLNM
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.66|      28|      33|     741|     769|      13
---------------------------------------------------------------------------
  741-  759 (24.21/ 9.92)	................LSSLTSA..GQAGHQQTSLAP
  761-  795 (32.01/17.09)	TQSIAVNTPgisasplLAEFTSAdgGQVS..VPTQVP
  796-  818 (30.45/11.57)	TKSSAAERP.......LDRLLKA..LEHGFER.....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09875 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLL
2) MSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQK
3) PISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIA
4) PLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRL
5) QQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMY
7
414
674
775
611
285
607
765
808
655










Molecular Recognition Features






MoRF SequenceStartStop




1) LEHGFERY
2) RPLDRLLK
812
803
819
810