<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09873

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKALRTTQPESLSAAVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFITHDGSGASKRMKRDTGAMPLNVSSAGSLNDSLKQSYTVGTPELQSTATSRVKCQRAEVNHVLLEEIQEINKQLIDTELHVSEDDAESFTTSDMAEGTVIKCTFTAVAVSPSLKSMFASAQMSPILPLRLLVPGSYPKCSPVLLDKFPDEQCRNSDDLSTKAKSKFSVLLRGLAEPMSLREIARTWDACARKVIAEYAQQTGGGSFSSSYGCWESCVGAS
Length560
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.04
Grand average of hydropathy-0.454
Instability index56.33
Isoelectric point8.67
Molecular weight60330.37
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP09873
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.16|      14|      15|      30|      43|       1
---------------------------------------------------------------------------
   14-   27 (19.71/ 9.72)	QGALNAQHQSNSNM
   30-   43 (22.32/12.20)	NNAMSTMQTNTNAM
   64-   77 (23.13/12.97)	NQQMKQRQQMLQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.17|      20|      20|      78|      97|       2
---------------------------------------------------------------------------
   78-   97 (34.19/18.29)	QQ.........KKILQQ.....QLPIQQLQKQQQ
  104-  131 (20.90/ 8.39)	QQlhsgndvneLKV.RQ.....GAAIKSGMYQPL
  132-  155 (22.08/ 9.27)	NQ.........RNYYQQikrgdVFPISSPQNLQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.88|      57|      70|     185|     243|       3
---------------------------------------------------------------------------
  185-  243 (95.80/56.91)	SANSPFVPSPSP.PVAPSPV..PLdsDKPLSNLSSL..TSAGQAGHQQTSLAPLTQSIAVNTPG
  255-  316 (80.08/42.05)	SADGGQVSVPTQvPTKSSAAerPL..DRLLKALRTTqpESLSAAVSDIGSVVSMIDRIAGSAPG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP09873 with Med15 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQK
2) PISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSI
3) QKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMY
4) SADGGQVSVPTQVPTKSSAAERPLDRLLKALRTT
1
147
93
255
80
237
128
288

Molecular Recognition Features

MoRF SequenceStartStop
NANANA