<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09871

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKALRTTQPESLSAAVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFITHDGSGASKRMKRDTGAMPLNVSSAGSLNDSLKQSYTVGTPELQSTATSRVKCQRAEVNHVLLEEIQEINKQLIDTELHVSEDDAESFTTSDMAEGTVIKCTFTAVAVSPSLKSMFASAQMSPILPLRLLVPGSYPKCSPVLLDKFPDEQCRNSDDLSTKAKSKFSVLLRGLAEPMSLREIARTWDACARKVIAEYAQQTGGGSFSSSYGCWESCVGAS
Length1168
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.743
Instability index69.04
Isoelectric point9.27
Molecular weight128351.37
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09871
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     156.10|      41|      43|     196|     238|       2
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  196-  231 (65.52/18.04)	......QPTQQPNIPLQQ.QPQQLMGHQS.NLQQNQLVNQQSGA
  234-  275 (45.94/10.74)	MQQQQrLPVQSTNLLNMH.QTQQMMNQQSmPLHQPQQLANQ.GN
  669-  708 (44.64/ 7.19)	MMQNQ.QMKQRQQM.LQQmQQKKILQQQL.PIQQLQ.KQQQQGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     901.70|     133|     233|     489|     621|       3
---------------------------------------------------------------------------
    1-   65 (61.68/10.48)	............................................MSQQ.Q..T....RQPNA...STS..VQGS..........LPSVGQNL.....................SS........................................VS..QTLTLQNLSGMPQ..........................NTMNN.G......LAQGTPQDMyaaqRQM......
   66-  172 (127.02/30.17)	........AGRQQ.QQQQQQAHN...................QFMYQQQKllMNQKLQQNSRmqpHIQQQ.QTL..........LQS..TQMQSSQQPMVQ.....MSSGLQPGQ........................................IA..IPQTQ...SMAMQSATQ.SGI.............QQNALNSVQQ..PVQSL.LQQ....P..............
  299-  419 (126.01/29.87)	QQQKPIQQPQQQQHAQQ......tsmglmqpqsqqnqlqqpqQHM...........MSQFQS...QPNQ.TQQQ..........L.GMQQRLQTSAGMLLQ.....QNNIDQQKQ........................................Y....VQAQKVLQEAPSTSVDSTAQ.............TGH...P.GT.GDSQEE.LYQMIKSLK....D........
  420-  497 (84.75/17.43)	...........QYFAELNDVYNK...................ISMK..........IQNIDN...H...MPAQ...............KSAEQYERLKGFK.....GM.......................................................LERILHFLQA..NKSSI.............Q.....P.........G.FREKISIFE....RQILSIMSS
  498-  627 (229.41/61.02)	QRRKPVQAPGQQTFQQSGGQAPS...................SNMSQQHQ..TSQGLQQHDS...HTNQMPQAS..........LPSMNTGVPTSGAPGIQ.....HVPAPQASN........................................FG..VPTTQQNVTNAPQAASNPENA.............QGNNFNPVQH.GSMGTA.LQQGSTGPM....QGALN...A
  628-  746 (89.37/18.82)	QH............QSNSNMISN...................NAMS............TMQT...NTNAM.QAN..........VNSLQQLK........Q.....H....QEHQmmqnqqmkqrqqmlqqmqqkkilqqqlpiqqlqkqqqqgpIQ..V...QQ.............LH.............SGNDVNELK..VRQGAA.IKSGMYQPL....NQ..RNYYQ
  747-  845 (105.39/23.65)	QIKR......GDVF.......PI...................SS.PQNLQ..ASSPQISHYS...HVDQ...HS..........L..LQSQVKT.GTP.LHsanspFVPSPSP...............................................PVAPSPV...PLDSDKP.................LSNLSSLT...SAGQAgHQQTSLAPL...tQSI......
  846-  967 (78.07/15.42)	....AVNTPG..........ISA...................SPLLAEFT..SADGGQV..S...VPTQVPTKSsaaerpldrlLKALRTTQPESLSAAV.............SD........................................IGsvVSMIDRIAGSAPGNGS..RAAvgedlvamtkcrlQARNF..ITHdGSGASK.RMKRDTGAM.............
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09871 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLL
2) MSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQK
3) PISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSI
4) QQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMY
5) SADGGQVSVPTQVPTKSSAAERPLDRLLKALRTT
1
495
755
692
863
366
688
845
736
896










Molecular Recognition Features






MoRF SequenceStartStop




NANANA