<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09866

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKALRTTQPESLSAAVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFITHDGSGASKRMKRDTGAMPLNVSSAGSLNDSLKQSYTVGTPELQSTATSRVKCQRAEVNHVLLEEIQEINKQLIDTELHVSEDDAESFTTSDMAEGTVIKCTFTAVAVSPSLKSMFASAQMSPILPLRLLVPGSYPKCSPVLLDKFPDEQCRNSDDLSTKAKSKFSVLLRGLAEPMSLREIARTWDACARKVIAEYAQQTGGGSFSSSYGCWESCVGAS
Length1307
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.727
Instability index65.91
Isoelectric point9.32
Molecular weight143283.12
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09866
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     639.64|      62|      64|     236|     297|       2
---------------------------------------------------------------------------
   68-  145 (48.64/ 8.07)	L.TElH..........KIAVRFEEkiytaatsqsdylrkiSLKMLSmESQKK...........................TQQ.......NPG........NAQVI...P....NQN..PP...G........PG....S.N...PA.....QSSAI........PLM.SQQQ..T
  146-  188 (46.70/ 7.42)	R.QP.N.................A................STSVQG.SLPS............................VGQ.......N...................lsSVSQT..LT...L........QN....L.S...GM..................PQN.TMNN..G
  189-  268 (89.74/21.97)	L.AQ.GtpqdmyaaqrQMAGRQQQ................QQQQQA.HNQFM...........................YQQ.......QKLlmnqklqqNSRMQ...P..HIQQQ..QT...L........LQ....S.T...QM.....QSSQQ........PMV.QMSS..G
  269-  333 (79.73/18.58)	L.QP.G..........QIAIPQTQ................SMAMQS.ATQSG...........................IQQ.......NAL........NSVQQ...P...V.....QS...L........LQqptpSvV...RQ.....QQHPQ........SMH.QQSSlqQ
  334-  402 (74.09/16.68)	T.QPtQ..........QPNIPLQQ................QPQQLM.GHQSN...........................LQQ.......NQL.....vnqQSG.A...V..EMQQQ..QR...L.......pVQ....S.TnllNM.....HQTQQ........MMN.QQSM..P
  403-  458 (71.84/15.92)	LhQP.Q..........QLA.NQGN...................VSS.LNQQ.............................QQ.......QLL....gtvpNVRM.......HMLQQ..QK...P........IQ....Q.P...QQ.....QQHAQ............QTSM..G
  474-  522 (54.49/10.05)	................QHMMSQFQ................SQPNQT.QQQLG.......................................M........QQRLQ...T.....SA..GM...L........LQ....Q.N...NI.....D.QQK........QYV.QAQK..V
  672-  763 (49.49/ 8.36)	L.Q.............QH.DSHTN................QMP.QA.SLPSMntgvptsgapgiqhvpapqasnfgvptTQQ.......NVT........NAPQAasnP..E.NAQ..GNnfnP........VQ....H.G...SMgtalqQGSTG........PM....QG..A
  764-  827 (65.57/13.80)	L.N...............AQHQSN................SNMISN.NAMST...........................MQT.......N.T........NA.MQ...A..NVNSL..QQ...LkqhqehqmMQ....N.Q...QM.....KQRQQ........MLQ.QMQQ..K
  830-  906 (59.36/11.70)	L.QQ............QLPIQQLQ................KQQQQG.PIQ.............................VQQlhsgndvNEL........KVRQG...A..AIKSGmyQP...L........NQ....R.N...YY.....QQIKRgdvfpissPQNlQASS..P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.93|      22|      25|     596|     618|       3
---------------------------------------------------------------------------
  575-  598 (22.13/ 9.15)	..IQN.IDNHM..PAQKSAEQ..yerlkGFK
  599-  620 (39.68/22.90)	GMLER.ILHFL..QANKSSIQ.P.....GFR
  624-  651 (18.12/ 8.05)	SIFERqILSIMssQRRK.PVQaP..gqqTFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     102.75|      26|      33|     964|     989|       4
---------------------------------------------------------------------------
  918-  938 (25.30/ 9.33)	...SL..LQSQVKTGTP............LHSA..NSPFV
  939-  972 (30.89/13.26)	PSPS.PPVAPS...PVPldsdkplsnlssLTSA..GQAGH
  973- 1009 (23.10/ 7.78)	QQTSLAPLTQSIAVNTP..gisaspllaeFTSAdgGQVS.
 1010- 1036 (23.47/ 8.04)	.VPTQVP.TKSSAAERP.........ldrLLKA..LRTTQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09866 with Med15 domain of Kingdom Viridiplantae
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