<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09863

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLLQQNNIDQQKQYVQAQKVLQEAPSTSVDSTAQTGHPGTGDSQEELYQMIKSLKDQYFAELNDVYNKISMKIQNIDNHMPAQKSAEQYERLKGFKGMLERILHFLQANKSSIQPGFREKISIFERQILSIMSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQKKILQQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMYQPLNQRNYYQQIKRGDVFPISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSIAVNTPGISASPLLAEFTSADGGQVSVPTQVPTKSSAAERPLDRLLKAVSNLPPSCLLSFDN
Length906
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.892
Instability index74.47
Isoelectric point9.77
Molecular weight100362.98
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09863
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     451.82|      63|      64|     553|     615|       3
---------------------------------------------------------------------------
   36-  104 (64.38/10.00)	...QN.LSGMPQNTMNNGLAQ...GT..................PQdmyaaqrQMAGRQQQQQQQQA.HNQFMY.Q.........QQK....LLMNQ...KlQQNS....rmQ........PHI
  105-  156 (63.09/ 9.60)	QQQQTlLQSTQMQSSQQPMVQ...................................MS....SGLQP.GQIAIP.Q.........TQS....MAMQS...A.TQSG......I........QQN
  223-  280 (66.95/10.79)	QLVNQ.QS....G.AVEMQQQ..QRL..................PV.......QSTNLLNMHQTQQMmNQQSMPlH.........QPQ....QL..A...N.QGNV......S........SLN
  296-  374 (52.87/ 6.46)	HMLQQ.QKPIQQPQQQQHAQQ..TSMglmqpqsqqnqlqqpqqhMM.......SQ...FQSQPNQTQ.QQLGMQ.QrlqtsagmlLQQ....N..NI...D.QQ....................
  553-  595 (60.69/ 8.87)	.......................TGV..................PT.......SGAPGIQHVPAPQA.SNFGVP.T.........TQQ....NVTNA...P.QAAS......N........PEN
  596-  667 (74.73/13.18)	AQGNN.FNPVQHGSMGTALQQgsTG...................PM.......QGALNAQHQSNSNMiSNNAMS.T.........MQT....N.TNA...M.QANV......NslqqlkqhQEH
  668-  740 (69.11/11.45)	QMMQN.QQMKQRQQMLQQMQQ..KKI..................LQ.......QQLP.IQQLQKQQQ.Q..GPI.Q.........VQQlhsgNDVNElkvR.QGAAiksgmyQ........PLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.56|      28|      35|     803|     830|       4
---------------------------------------------------------------------------
  766-  800 (24.79/10.28)	..SPQISHySHVDqhsllqsqVK..........TGTPLHSANSPFVP
  801-  828 (49.46/30.19)	SPSPPVAP.SPVP........LD..........SDKPLSNLSSLTSA
  829-  864 (31.31/15.54)	GQAGHQQT.SLAP........LTqsiavntpgiSASPL..LAEFTSA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.20|      16|     241|     515|     530|       7
---------------------------------------------------------------------------
  515-  530 (30.61/10.48)	GGQAPSSNMSQQHQTS
  532-  547 (29.59/ 9.84)	GLQQHDSHTNQMPQAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.74|      21|     203|       4|      25|       9
---------------------------------------------------------------------------
    4-   24 (37.83/23.19)	QQTRQPNASTSV....QGSLPSVGQ
  381-  405 (32.91/14.13)	QKVLQEAPSTSVdstaQTGHPGTGD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09863 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLANQGNVSSLNQQQQQLLGTVPNVRMHMLQQQKPIQQPQQQQHAQQTSMGLMQPQSQQNQLQQPQQHMMSQFQSQPNQTQQQLGMQQRLQTSAGMLL
2) MSSQRRKPVQAPGQQTFQQSGGQAPSSNMSQQHQTSQGLQQHDSHTNQMPQASLPSMNTGVPTSGAPGIQHVPAPQASNFGVPTTQQNVTNAPQAASNPENAQGNNFNPVQHGSMGTALQQGSTGPMQGALNAQHQSNSNMISNNAMSTMQTNTNAMQANVNSLQQLKQHQEHQMMQNQQMKQRQQMLQQMQQK
3) PISSPQNLQASSPQISHYSHVDQHSLLQSQVKTGTPLHSANSPFVPSPSPPVAPSPVPLDSDKPLSNLSSLTSAGQAGHQQTSLAPLTQSI
4) QQQLPIQQLQKQQQQGPIQVQQLHSGNDVNELKVRQGAAIKSGMY
1
495
755
692
366
688
845
736










Molecular Recognition Features






MoRF SequenceStartStop




1) RPLDRLLK
884
891