<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09861

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETLKKHLPVSVPEGLTELHKIAVRFEEKIYTAATSQSDYLRKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPEPGLPPQGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLAKSAAAAASWNRAKCPYAYVTATKANSATTAATACSADINGFDATSVSAESASATSTTYDVAVPVSA
Length483
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.03
Grand average of hydropathy-0.749
Instability index73.39
Isoelectric point9.54
Molecular weight52579.23
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09861
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     154.32|      25|      26|     316|     340|       1
---------------------------------------------------------------------------
  125-  155 (31.53/ 6.32)	PGPEPGLPPQGSNPaQSsaiplMSQQQTRQP
  216-  236 (33.82/ 7.36)	QQQQ....QQQAHN.QF.....MYQQQKLLM
  316-  340 (49.04/14.28)	QQPTPSVVRQQQHP.QS.....MHQQSSLQQ
  343-  367 (39.92/10.13)	PTQQPNIPLQQQPQ.QL.....MGHQSNLQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.09|      19|      21|     369|     389|       2
---------------------------------------------------------------------------
  254-  271 (28.83/ 8.26)	QTLLQST...QMQSSQQPMVQ
  369-  389 (30.80/13.85)	QLVNQQSgaVEMQQQQRLPVQ
  401-  416 (25.46/ 6.32)	QMMNQQS..MPLHQPQQL...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.19|      19|      22|     437|     455|       3
---------------------------------------------------------------------------
  417-  431 (19.73/10.29)	....AKSAAAAASWNRAKC
  437-  455 (31.05/20.42)	TATKANSATTAATACSADI
  461-  477 (26.41/16.27)	TSVSAESAS..ATSTTYDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.54|      28|     110|     163|     193|       4
---------------------------------------------------------------------------
  162-  191 (38.58/18.51)	QGSLPSvGQNLSSVSQTLTLQ..nLSGMPQNT
  273-  303 (42.96/17.83)	SSGLQP.GQIAIPQTQSMAMQsatQSGIQQNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09861 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDGAANWRPTQGADPATVAAVGGVDPNAAAPTGSDWRTQLQPEARQRIVNKIMETL
2) RKISLKMLSMESQKKTQQNPGNAQVIPNQNPPGPEPGLPPQGSNPAQSSAIPLMSQQQTRQPNASTSVQGSLPSVGQNLSSVSQTLTLQNLSGMPQNTMNNGLAQGTPQDMYAAQRQMAGRQQQQQQQQAHNQFMYQQQKLLMNQKLQQNSRMQPHIQQQQTLLQSTQMQSSQQPMVQMSSGLQPGQIAIPQTQSMAMQSATQSGIQQNALNSVQQPVQSLLQQPTPSVVRQQQHPQSMHQQSSLQQTQPTQQPNIPLQQQPQQLMGHQSNLQQNQLVNQQSGAVEMQQQQRLPVQSTNLLNMHQTQQMMNQQSMPLHQPQQLAKSAAAA
1
94
56
423










Molecular Recognition Features






MoRF SequenceStartStop




1) MDGAANWR
2) YLRKISLKMLS
1
92
8
102