<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09851

Description Polymerase II transcription-mediator1
SequenceMQRYAGFSGSRDGARLEASPFSSSSSSGYPVSSRRQQQLTPYKLKCDKDPLNNKLGPPDFYPQTLNCPEETLTKDYVQYGYKETVEGIEEAREIVISQIPYFCKPDVVIKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDTRRKWVEALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQLQARPAPNSTSVVASDNQRSNQWTKDVVEYLQQILDEVCSKEGAIVPPSFKEQSSPGLAAGTNQIKMKTESSPAGDSEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSDDVLELLLPIILGLVDTITLSQTYVRMFVELLVRRLNVDRPKRFSVSSVIAELLRYMVLAVPDTFVSLDCFPFPSFVVPDVYGRGALLKITSGGGILCSKRRDAYRYLSCGYAVSSIQKRAHDLAAVANPSLQARGAAKVVQALDKALVTGNLSVAYFSLFNDLSDALMEERWIKEVNPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSQNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRPKSSTRITLNKVAKGSLNDACLTAAAVDDSSGLRSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSNVAGFTRVDVLIAELIRNGIFFPQVYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDVLEETRTAEEQQLYEMMSTYSSERRLVLSELSCGHSFYASGRGEYTSSSCIRKQSDLPVASEGDKHGRVLEQVEDVKALLSSLLGFTYPPLVESKLCEIKTSFQESVTSTLTQVETGEAKSGCEDCMRSKGQKLDDSATPFQGFPLIQSGEEDIWWVKKGTKLQESFNVEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGASTSHVCESKMSCPHHEPNNDGDNVKDFDHTRAANVTAIGKSLKRLRLLERRSVSSWLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEELLSVLYVLDTCCDSVSGVKFLIWLLVKIRGVGSSGQPGRTYMLMRNRDHQVCQVNEALVFSSLLRYENILLATDILPDVLSALVNRNSMSATTRHPGSTAFAYVRYFLKKYRDVASVAKWEKNFRTTCDQRLLAELDNGRSIDGDLVSSSGILAGEEIDEQVRQKLNGRSSRLVQNMKEIVQRQADGIQRSLKEKKVLAGAAPRNPLTFEKEDSYQIAHDIVLGLVECIRQNGGANPDGDLSIVASAVSAIVVNAGHMIAKHLDFAGGNYQGVNSVATSLNFVRHTLLIHINSLCLLKETLGDRFSRAFEIALAVETSAAVTAAFAPPKMHRNQFQPSPEAHDAYGNHTSELSNSGKGFVGRTAKVSAAISALVVGAVVHGAVSLERMVATLKIKDGLDIMQLLRGLKSNTNGVSHPTGGFRIENSTEVSVHWFRILLGNCRTVYDGLIADILGDPYIIALSRLQRMLPLTVIFPPAYSIFAMVLWRRYIFNCEDPQLYQSFSNAINDITRHQPFREIYFRNTHRLYNLLASDVGDSKFAAMLESHSPDRNSKILPFIPLRARLFLDAIIDCNTPTIQGDGASEPCDPKDNELKLSERLMQLLDTLQPAKFHWQWVEMRLLLDEQALMEKVAAGKTTLESLRSLSPKAEGFALSDSEKGFTEVILSRLLARPDAAPLYSELVHLLGKLQESLVMDVKWILQGQDAILGRRSTRQQLVHIAQRKGLSTKAQVWKPWGWSSLLSDAIPNKT
Length1779
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.07
Grand average of hydropathy-0.256
Instability index45.23
Isoelectric point8.73
Molecular weight198532.86
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09851
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     254.07|      85|     416|    1164|    1268|       1
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  252-  355 (125.56/68.05)	LDEVCSKEGAIVppsfkeqSSPGLAAGtNQIKMKTESSPAGDSEEPLVHFK..WRYMVRLIQWHLTEELLVPSvliewlsnqlqERDSDDVLELLLPIILGLVDTI
 1166- 1259 (128.52/102.25)	LDNGRSIDGDLV.......SSSGILAG.EEIDEQVRQKLNGRSSRLVQNMKeiVQRQADGIQRSLKEKKVLAG....aaprnplTFEKEDSYQIAHDIVLGLVECI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.96|      46|     414|    1089|    1142|       3
---------------------------------------------------------------------------
 1089- 1142 (58.40/56.14)	VFSSLLRYENILLATDilPDVLSALvnRNSMSATTRHpgsTAFAYVrYFLKKYR
 1510- 1555 (86.56/52.04)	IFAMVLWRRYIFNCED..PQLYQSF..SNAINDITRH...QPFREI.YFRNTHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.92|      48|     415|     921|     972|       4
---------------------------------------------------------------------------
  921-  972 (70.80/70.12)	AARIEGSqGASTSHVCESKMSCPHHEPNNDGDNVKDfDHTraANVTAIGKSL
 1342- 1389 (83.12/62.50)	ALAVETS.AAVTAAFAPPKMHRNQFQPSPEAHDAYG.NHT..SELSNSGKGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.67|      11|      18|      41|      51|       7
---------------------------------------------------------------------------
   41-   51 (21.59/12.50)	PYKLKCDKDPL
   62-   72 (21.08/12.03)	PQTLNCPEETL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.58|      15|     533|     758|     776|      10
---------------------------------------------------------------------------
  741-  756 (22.55/ 9.41)	STYSSERRLVLSElSC
  759-  773 (29.04/16.82)	SFYASGRGEYTSS.SC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.84|      13|      18|     369|     386|      11
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  369-  381 (22.37/19.60)	LVRRLNVDRPKRF
  390-  402 (22.47/ 7.12)	LLRYMVLAVPDTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.63|      22|     416|     855|     882|      13
---------------------------------------------------------------------------
  843-  865 (37.74/32.79)	KSGCEDC.MRSKgQKLDDS..ATPFQ
  871-  896 (25.88/15.76)	QSGEEDIwWVKKgTKLQESfnVEPVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.69|      14|      18|     657|     670|      16
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  657-  670 (23.50/15.93)	VSNVAGFTRVDV..LI
  674-  689 (21.18/13.54)	IRNGIFFPQVYVrqLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.63|      45|     660|     986|    1030|      17
---------------------------------------------------------------------------
  986- 1030 (76.30/46.96)	WLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEE
 1643- 1687 (73.33/44.85)	WQWVEMRLLLDEQALMEKVAAGKTTLESLRSLSPKAEGFALSDSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.47|      27|     891|     802|     829|      19
---------------------------------------------------------------------------
  802-  829 (43.11/31.06)	LLSSLLGF.TYPPLVeSKLCEIKTSFQES
 1694- 1721 (40.36/24.15)	ILSRLLARpDAAPLY.SELVHLLGKLQES
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09851 with Med12 domain of Kingdom Viridiplantae
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