<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09848

Description Polymerase II transcription-mediator1
SequenceMQRYAGFSGSRDGARLEASPFSSSSSSGYPVSSRRQQQLTPYKLKCDKDPLNNKLGPPDFYPQTLNCPEETLTKDYVQYGYKETVEGIEEAREIVISQIPYFCKPDVVIKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDTRRKWVEALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQLQARPAPNSTSVVASDNQRSNQWTKDVVEYLQQILDEVCSKEGAIVPPSFKEQSSPGLAAGTNQIKMKTESSPAGDSEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSDDVLELLLPIILGLVDTITLSQTYVRMFVELLVRRLNVDRPKRFSVSSVIAELLRYMVLAVPDTFVSLDCFPFPSFVVPDVYGRGALLKITSGGGILCSKRRDAYRYLSCGYAVSSIQKRAHDLAAVANPSLQARGAAKVVQALDKALVTGNLSVAYFSLFNDLSDALMEERWIKEVNPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSQNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRPKSSTRITLNKVAKGSLNDACLTAAAVDDSSGLRSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSNVAGFTRVDVLIAELIRNGIFFPQVYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDVLEETRTAEEQQLYEMMSTYSSERRLVLSELSCGHSFYASGRGEYTSSSCIRKQSDLPVASEGDKHGRVLEQVEDVKALLSSLLGFTYPPLVESKLCEIKTSFQESVTSTLTQVETGEAKSGCEDCMRSKGQKLDDSATPFQGFPLIQSGEEDIWWVKKGTKLQESFNVEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGASTSHVCESKMSCPHHEPNNDGDNVKDFDHTRAANVTAIGKSLKRLRLLERRSVSSWLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEELLSVLYVLDTCCDSVSGVKFLIWLLVKIRGVGSSGQPGRTYMLMRNRDHQVCQV
Length1084
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.07
Grand average of hydropathy-0.342
Instability index50.20
Isoelectric point8.73
Molecular weight121488.44
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09848
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.13|      25|      87|      50|      74|       2
---------------------------------------------------------------------------
   50-   74 (48.54/27.47)	PLNNK.LGPPDFYPQTLNCPEETLTK
  139-  164 (42.59/23.28)	PLSGSlLIKPGVYPEQRPCNEDTRRK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     382.77|     128|     171|     243|     384|       3
---------------------------------------------------------------------------
  243-  384 (181.23/148.04)	DVveYLQQILDEVCSKEGAIVP...PSFKEQSSpGLAAGTNQIKMKTESSPAGDSeeplvhFKWRYMVRLIQwHLTEELLVPSVLIEWLS..NQL.....QERDSDDVLELLLPIILgLVDTITLSqTYVRMFveLLVRRLNVD.RPKRFSVS
  417-  555 (201.55/121.59)	DV..YGRGALLKITSGGGILCSkrrDAYRYLSC.GYAVSSIQKRAHDLAAVANPS......LQARGAAKVVQ.ALDKALVTGNLSVAYFSlfNDLsdalmEERWIKEVNPCLQSSLM.WIGTVELS.LICSIF..FLCEWATCDyRDCRASPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.45|      15|      19|     652|     670|       4
---------------------------------------------------------------------------
  652-  670 (19.41/25.09)	LdqheVSNVAGFTRVDV..LI
  673-  689 (22.04/14.23)	L....IRNGIFFPQVYVrqLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.80|      13|      28|     853|     865|       6
---------------------------------------------------------------------------
  853-  865 (24.39/16.23)	KGQKLDDS..ATPFQ
  882-  896 (18.41/10.35)	KGTKLQESfnVEPVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      95.62|      23|      89|     897|     919|       8
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  897-  919 (36.03/20.84)	KSVKQTSRGRAKVVRK.TQSLAQL
  970-  988 (28.92/15.41)	KSLK...RLRL.LERR.SVSSWLL
  989- 1012 (30.67/16.74)	KSIRQLVDGNGMTASKaTNSISIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09848 with Med12 domain of Kingdom Viridiplantae
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