<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09846

Description Polymerase II transcription-mediator1
SequenceMPGAPLRRQQQLTPYKLKCDKDPLNNKYEAREIVISQIPYFCKPDVVIKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDTRRKWVEALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQARPAPNSTSVVASDNQRSNQWTKDVVEYLQQILDEVCSKEGAIVPPSFKEQSSPGLAAGTNQIKMKTESSPAGDSEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSDDVLELLLPIILGLVDTITLSQTYVRMFVELLVRRLNVDRPKRFSVSSVIAELLRYMVLAVPDTFVSLDCFPFPSFVVPDVYGRGALLKITSGGGILCSKRRDAYRYLSCGYAVSSIQKRAHDLAAVANPSLQARGAAKVVQALDKALVTGNLSVAYFSLFNDLSDALMEERWIKEVNPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSQNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRPKSSTRITLNKVAKGSLNDACLTAAAVDDSSGLRSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSNVAGFTRVDVLIAELIRNGIFFPQVYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDVLEETRTAEEQQLYEMMSTYSSERRLVLSELSCGHSFYASGRGEYTSSSCIRKQSDLPVASEGDKHGRVLEQVEDVKALLSSLLGFTYPPLVESKLCEIKTSFQESVTSTLTQVETGEAKSGCEDCMRSKGQKLDDSATPFQGFPLIQSGEEDIWWVKKGTKLQESFNVEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGASTSHVCESKMSCPHHEPNNDGDNVKDFDHTRAANVTAIGKSLKRLRLLERRSVSSWLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEELLSVLYVLDTCCDSVSGVKFLIWLLVKIRGVGSSGQPGRTYMLMRNRDHQVCQVNEALVFSSLLRYENILLATDILPDVLSALVNRNSMSATTRHPGSTAFAYVRYFLKKYRDVASVAKWEKNFRTTCDQRLLAELDNGRSIDGDLVSSSGILAGEEIDEQVRQKLNGRSSRLVQNMKEIVQRQADGIQRSLKEKKVLAGAAPRNPLTFEKEDSYQIAHDIVLGLVECIRQNGGANPDGDLSIVASAVSAIVVNAGHMIAKHLDFAGGNYQGVNSVATSLNFVRHTLLIHINSLCLLKETLGDRFSRAFEIALAVETSAAVTAAFAPPKMHRNQFQPSPEAHDAYGNHTSELSNSGKGFVGRTAKVSAAISALVVGAVVHGAVSLERMVATLKIKDGLDIMQLLRGLKSNTNGVSHPTGGFRIENSTEVSVHWFRILLGNCRTVYDGLIADILGDPYIIALSRLQRMLPLTVIFPPAYSIFAMVLWRRYIFNCEDPQLYQSFSNAINDITRHQPFREIYFRNTHRLYNLLASDVGDSKFAAMLESHSPDRNSKILPFIPLRARLFLDAIIDCNTPTIQGDGASEPCDPKDNELKLSERLMQLLDTLQPAKFHWQWVEMRLLLDEQALMEKVAAGKTTLESLRSLSPKAEGFALSDSEKGFTEVILSRLLARPDAAPLYSELVHLLGKLQESLVMDVKWILQGQDAILGRRSTRQQLVHIAQRKGLSTKAQVWKPWGWSSLLSDAIPNKTAKRKLEVTSIEEGEVVDDTVDAKRTTKTPPHSVDRSFEGIRSINKYLTEKALAELVLPCIDRSSADIRGILSVDLTKQMGAISEHIKAIALNGAKQAGSVSSGNEVPSNKSSGRRGIRGGSPNIGRRAPVGNDPSPPSASALRAALWLRLQFIIRLLPVIMADRSMRHTLASAILGLLATRMIYEDADLPLPPTNATALRRDVDSLLEPPLDVLLDRPGESLFEKLLCVLHALLGSYKPSWLKSRSASRSSIKSQRDFSAFDNEAAEGLQSALDHMELPETIRRRIQAAMPLLPPSRRPCMQCQPPQLSLAALSPLQSSTSGVGPQQKSSCVSWVPTNVSVRSKAALPSHDPETEVDPWSLLEDGTNCPPSTASGSNGSSGVTGDHANLKASSWLKGAVRVRRTELTYIGSVDDDS
Length2132
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.249
Instability index47.80
Isoelectric point8.86
Molecular weight236309.81
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09846
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.39|      26|      64|     919|     980|       1
---------------------------------------------------------------------------
  949-  975 (41.43/73.33)	LPLQPDDKTASKWRLgDEELLSVLYVL
 1905- 1930 (45.96/ 8.78)	LPLPPTNATALRRDV.DSLLEPPLDVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.09|      26|      64|      75|     100|       2
---------------------------------------------------------------------------
   75-  100 (49.11/26.95)	YGVP.LSGSLLIKPGVYPEQRPCNEDT
  138-  164 (43.98/23.42)	YNVPlLRATWFIKVTYLNQARPAPNST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     162.63|      40|      63|    2018|    2058|       3
---------------------------------------------------------------------------
  685-  711 (27.18/ 9.79)	.....RLVLSELSCGHSfYASGRGEYTSSSCI..........
 2018- 2058 (70.96/42.41)	QCqPPQLSLAALSPLQS.STSGVGPQQKSSCVSWVPTNVSVR
 2083- 2118 (64.49/34.31)	NC.PP..STASGSNGSS.GVTGDHANLKAS..SWLKGAVRVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.22|      16|      64|     919|     940|       4
---------------------------------------------------------------------------
  919-  940 (23.90/24.53)	SVSS.....WLLKSIRqlvdgnGMTAS
  981- 1001 (24.31/11.44)	SVSGvkfliWLLVKIR......GVGSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     452.95|     141|     299|     445|     597|       5
---------------------------------------------------------------------------
  445-  597 (224.52/172.23)	ERWIKEVNPCLQ....SSLMWIGTVELSLICSiffLCEWATCDYRDCRASPSQNVKF..TGRRDLSQIHMAvsilkNKMDEMNNLSRPKSSTRIT...LNKVAKGSLNDACLTAAAVDDSSGlrSNAKNVDEKKDTNDIFEsPGPLHDiIVCWLDQHEVSNV
  753-  902 (228.43/144.31)	ESKLCEIKTSFQesvtSTLTQVETGEAKSGCE...DCMRSKGQKLDDSATPFQGFPLiqSGEEDIWWVKKG.....TKLQESFNVEPVQKSVKQTsrgRAKVVRKTQSLAQLAAARIEGSQG..ASTSHVCESKMSCPHHE.PNNDGD.NVKDFDHTRAANV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.61|      33|      63|    1316|    1348|       6
---------------------------------------------------------------------------
 1316- 1348 (52.64/35.65)	TSELSNSGKGF.VGRTAKVSAAISALVVG...AVVHG
 1378- 1414 (49.97/33.43)	TNGVSHPTGGFrIENSTEVSVHWFRILLGncrTVYDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.91|      41|      70|    1601|    1643|       7
---------------------------------------------------------------------------
 1601- 1637 (50.48/25.34)	.............................GKTTLESLRS....LSPKAEGFALSDSEKGFTEVILSRLLA
 1640- 1709 (47.13/26.63)	DAAPlyselvhllgklqeslvmdvkwilqGQDAILGRRStrqqLVHIAQRKGLSTKAQVWKPWGWSSLLS
 1710- 1771 (38.29/14.68)	DAIPnktakrklevtsieegevvddtvdaKRTTKTPPHS....VDRSFEG..IRSINKYLTEKALAEL..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.02|      38|     433|    1101|    1145|      11
---------------------------------------------------------------------------
 1101- 1145 (54.44/46.75)	AELD.NGRSIDGDlvsssGilAGEEIDEQVRQ.KLNGRSSRLVQNMK
 1535- 1574 (58.58/34.10)	AIIDcNTPTIQGD.....G..ASEPCDPKDNElKLSERLMQLLDTLQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09846 with Med12 domain of Kingdom Viridiplantae
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