<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09844

Description Polymerase II transcription-mediator1
SequenceMGIALQALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQLQARPAPNSTSVVASDNQRSNQWTKDVVEYLQQILDEVCSKEGAIVPPSFKEQSSPGLAAGTNQIKMKTESSPAGDSEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSDDVLELLLPIILGLVDTITLSQTYVRMFVELLVRRLNVDRPKRFSVSSVIAELLRYMVLAVPDTFVSLDCFPFPSFVVPDVYGRGALLKITSGGGILCSKRRDAYRYLSCGYAVSSIQKRAHDLAAVANPSLQARGAAKVVQALDKALVTGNLSVAYFSLFNDLSDALMEERWIKEVNPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSQNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRPKSSTRITLNKVAKGSLNDACLTAAAVDDSSGLRSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSNVAGFTRVDVLIAELIRNGIFFPQVYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDVLEETRTAEEQQLYEMMSTYSSERRLVLSELSCGHSFYASGRGEYTSSSCIRKQSDLPVASEGDKHGRVLEQVEDVKALLSSLLGFTYPPLVESKLCEIKTSFQESVTSTLTQVETGEAKSGCEDCMRSKGQKLDDSATPFQGFPLIQSGEEDIWWVKKGTKLQESFNVEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGASTSHVCESKMSCPHHEPNNDGDNVKDFDHTRAANVTAIGKSLKRLRLLERRSVSSWLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEELLSVLYVLDTCCDSVSGVKFLIWLLVKIRGVGSSGQPGRTYMLMRNRDHQVCQVNEALVFSSLLRYENILLATDILPDVLSALVNRNSMSATTRHPGSTAFAYVRYFLKKYRDVASVAKWEKNFRTTCDQRLLAELDNGRSIDGDLVSSSGILAGEEIDEQVRQKLNGRSSRLVQNMKEIVQRQADGIQRSLKEKKVLAGAAPRNPLTFEKEDSYQIAHDIVLGLVECIRQNGGANPDGDLSIVASAVSAIVVNAGHMIAKHLDFAGGNYQGVNSVATSLNFVRHTLLIHINSLCLLKETLGDRFSRAFEIALAVETSAAVTAAFAPPKMHRNQFQPSPEAHDAYGNHTSELSNSGKGFVGRTAKVSAAISALVVGAVVHGAVSLERMVATLKIKDGLDIMQLLRGLKSNTNGVSHPTGGFRIENSTEVSVHWFRILLGNCRTVYDGLIADILGDPYIIALSRLQRMLPLTVIFPPAYSIFAMVLWRRYIFNCEDPQLYQSFSNAINDITRHQPFREIYFRNTHRLYNLLASDVGDSKFAAMLESHSPDRNSKILPFIPLRARLFLDAIIDCNTPTIQGDGASEPCDPKDNELKLSERLMQLLDTLQPAKFHWQWVEMRLLLDEQALMEKVAAGKTTLESLRSLSPKAEGFALSDSEKGFTEVILSRLLARPDAAPLYSELVHLLGKLQESLVMDVKWILQGQDAILGRRSTRQQLVHIAQRKGLSTKAQVWKPWGWSSLLSDAIPNKTAKRKLEVTSIEEGEVVDDTVDAKRTTKTPPHSVDRSFEGIRSINKYLTEKALAELVLPCIDRSSADIRGILSVDLTKQMGAISEHIKAIALNGAKQAGSVSSGNEVPSNKSSGRRGIRGGSPNIGRRAPVGNDPSPPSASALRAALWLRLQFIIRLLPVIMADRSMRHTLASAILGLLATRMIYEDADLPLPPTNATALRRDVDSLLEPPLDVLLDRPGESLFEKLLCVLHALLGSYKPSWLKSRSASRSSIKSQRDFSAFDNEAAEGLQSALDHMELPETIRRRIQAAMPLLPPSRRPCMQCQPPQLSLAALSPLQSSTSGVGPQQKSSCVSWVPTNVSVRSKAALPSHDPETEVDPWSLLEDGTNCPPSTASGSNGSSGVTGDHANLKASSWLKGAVRVRRTELTYIGSVDDDS
Length2034
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.215
Instability index47.92
Isoelectric point8.60
Molecular weight224901.61
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09844
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     187.45|      59|      64|     821|     882|       1
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  821-  882 (95.41/58.86)	SvssWLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEELLSVLYVLDTCCD
 1454- 1480 (29.73/10.63)	...............................PCDPKD...NELKL.SERLMQLLDTLQPAKF
 1481- 1526 (62.31/31.74)	H...WQWVEMRLLLDEQALMEKVAAGKTTLESLRSLSPKAEGFALSDSE.............
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     452.95|     141|     300|     347|     499|       2
---------------------------------------------------------------------------
  347-  499 (224.52/233.80)	ERWIKEVNPCLQ....SSLMWIGTVELSLICSiffLCEWATCDYRDCRASPSQNVKF..TGRRDLSQIHMAvsilkNKMDEMNNLSRPKSSTRIT...LNKVAKGSLNDACLTAAAVDDSSGlrSNAKNVDEKKDTNDIFEsPGPLHDiIVCWLDQHEVSNV
  655-  804 (228.43/195.94)	ESKLCEIKTSFQesvtSTLTQVETGEAKSGCE...DCMRSKGQKLDDSATPFQGFPLiqSGEEDIWWVKKG.....TKLQESFNVEPVQKSVKQTsrgRAKVVRKTQSLAQLAAARIEGSQG..ASTSHVCESKMSCPHHE.PNNDGD.NVKDFDHTRAANV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.02|      28|     300|    1534|    1568|       3
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 1534- 1568 (38.94/37.47)	LSRLLARPDAApLYSELV...H.LLGKLQESlvmdvkWI
 1829- 1860 (42.08/22.64)	LDVLLDRPGES.LFEKLLcvlHaLLGSYKPS......WL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.39|      15|     300|     275|     289|       4
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  275-  289 (30.41/16.71)	SKRRDAYRYLSCG...YA
  584-  601 (22.98/10.90)	SERRLVLSELSCGhsfYA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.78|      35|      62|    1920|    1960|       7
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 1920- 1959 (50.86/42.34)	QCqPPqlSLAALSPLQSSTSGVGPQQKSScvSWVPTNVSV
 1985- 2019 (64.93/30.10)	NC.PP..STASGSNGSSGVTGDHANLKAS..SWLKGAVRV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     173.58|      56|     435|    1273|    1374|      14
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  113-  172 (85.04/46.41)	GLAAGTNQIKMKTESSPAGDSEEPLVHfkW.RYMV...RLIQWHLTEELLVPSVLIEwLSnQLQ
 1275- 1334 (88.54/151.58)	GLKSNTNGVSHPTGGFRIENSTEVSVH..WfRILLgncRTVYDGLIADILGDPYIIA.LS.RLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.38|      28|      28|    1721|    1748|      15
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 1721- 1748 (50.14/24.94)	GNE.VPSNKSSGRRGIRGGSPNIGRRAPV
 1749- 1777 (44.24/21.20)	GNDpSPPSASALRAALWLRLQFIIRLLPV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09844 with Med12 domain of Kingdom Viridiplantae
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