<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09843

Description Polymerase II transcription-mediator1
SequenceMQRYAGFSGSRDGARLEASPFSSSSSSGYPVSSRRQQQLTPYKLKCDKDPLNNKLGPPDFYPQTLNCPEETLTKDYVQYGYKETVEGIEEAREIVISQIPYFCKPDVVIKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDTRRKWVEALAQPNKRLRSLSEHVPHGYRRKSLFEGLIRYNVPLLRATWFIKVTYLNQLQARPAPNSTSVVASDNQRSNQWTKDVVEYLQQILDEVCSKEGAIVPPSFKEQSSPGLAAGTNQIKMKTESSPAGDSEEPLVHFKWRYMVRLIQWHLTEELLVPSVLIEWLSNQLQERDSDDVLELLLPIILGLVDTITLSQTYVRMFVELLVRRLNVDRPKRFSVSSVIAELLRYMVLAVPDTFVSLDCFPFPSFVVPDVYGRGALLKITSGGGILCSKRRDAYRYLSCGYAVSSIQKRAHDLAAVANPSLQARGAAKVVQALDKALVTGNLSVAYFSLFNDLSDALMEERWIKEVNPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRASPSQNVKFTGRRDLSQIHMAVSILKNKMDEMNNLSRPKSSTRITLNKVAKGSLNDACLTAAAVDDSSGLRSNAKNVDEKKDTNDIFESPGPLHDIIVCWLDQHEVSNVAGFTRVDVLIAELIRNGIFFPQVYVRQLIISGITDKNDTMLDVERKRRHHRTLKQLPGSSLFDVLEETRTAEEQQLYEMMSTYSSERRLVLSELSCGHSFYASGRGEYTSSSCIRKQSDLPVASEGDKHGRVLEQVEDVKALLSSLLGFTYPPLVESKLCEIKTSFQESVTSTLTQVETGEAKSGCEDCMRSKGQKLDDSATPFQGFPLIQSGEEDIWWVKKGTKLQESFNVEPVQKSVKQTSRGRAKVVRKTQSLAQLAAARIEGSQGASTSHVCESKMSCPHHEPNNDGDNVKDFDHTRAANVTAIGKSLKRLRLLERRSVSSWLLKSIRQLVDGNGMTASKATNSISILPLQPDDKTASKWRLGDEELLSVLYVLDTCCDSVSGVKFLIWLLVKIRGVGSSGQPGRTYMLMRNRDHQVCQVNEALVFSSLLRYENILLATDILPDVLSALVNRNSMSATTRHPGSTAFAYVRYFLKKYRDVASVAKWEKNFRTTCDQRLLAELDNGRSIDGDLVSSSGILAGEEIDEQVRQKLNGRSSRLVQNMKEIVQRQADGIQRSLKEKKVLAGAAPRNPLTFEKEDSYQIAHDIVLGLVECIRQNGGANPDGDLSIVASAVSAIVVNAGHMIAKHLDFAGGNYQGVNSVATSLNFVRHTLLIHINSLCLLKETLGDRFSRAFEIALAVETSAAVTAAFAPPKMHRNQFQPSPEAHDAYGNHTSELSNSGKGFVGRTAKVSAAISALVVGAVVHGAVSLERMVATLKIKDGLDIMQLLRGLKSNTNGVSHPTGGFRIENSTEVSVHWFRILLGNCRTVYDGLIADILGDPYIIALSRLQRMLPLTVIFPPAYSIFAMVLWRRYIFNCEDPQLYQSFSNAINDITRHQPFREIYFRNTHRLYNLLASDVGDSKFAAMLESHSPDRNSKILPFIPLRARLFLDAIIDCNTPTIQGDGASEPCDPKDNELKLSERLMQLLDTLQPAKFHWQWVEMRLLLDEQALMEKVAAGKTTLESLRSLSPKAEGFALSDSEKGFTEVILSRLLARPDAAPLYSELVHLLGKLQESLVMDVKWILQGQDAILGRRSTRQQLVHIAQRKGLSTKAQVWKPWGWSSLLSDAIPNKTAKRKLEVTSIEEGEVVDDTVDAKRTTKTPPHSVDRSFEGIRSINKYLTEKALAELVLPCIDRSSADIRGILSVDLTKQMGAISEHIKAIALNGAKQAGSVSSGNEVPSNKSSGRRGIRGGSPNIGRRAPVGNDPSPPSASALRAALWLRLQFIIRLLPVIMADRSMRHTLASAILGLLATRMIYEDADLPLPPTNATALRRDVDSLLEPPLDVLLDRPGESLFEKLLCVLHALLGSYKPSWLKSRSASRSSIKSQRDFSAFDNEAAEGLQSALDHMELPETIRRRIQAAMPLLPPSRRPCMQCQPPQLSLAALSPLQSSTSGVGPQQKSSCVSWVPTNVSVRSKAALPSHDPETEVDPWSLLEDGTNCPPSTASGSNGSSGVTGDHANLKASSWLKGAVRVRRTELTYIGSVDDDS
Length2195
PositionKinase
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.265
Instability index48.43
Isoelectric point8.75
Molecular weight243240.18
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09843
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.39|      26|      64|     982|    1043|       1
---------------------------------------------------------------------------
 1012- 1038 (41.43/88.05)	LPLQPDDKTASKWRLgDEELLSVLYVL
 1968- 1993 (45.96/10.68)	LPLPPTNATALRRDV.DSLLEPPLDVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     162.63|      40|      63|    2081|    2121|       2
---------------------------------------------------------------------------
  748-  774 (27.18/ 9.27)	.....RLVLSELSCGHSfYASGRGEYTSSSCI..........
 2081- 2121 (70.96/40.02)	QCqPPQLSLAALSPLQS.STSGVGPQQKSSCVSWVPTNVSVR
 2146- 2181 (64.49/32.38)	NC.PP..STASGSNGSS.GVTGDHANLKAS..SWLKGAVRVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.22|      16|      64|     982|    1003|       3
---------------------------------------------------------------------------
  982- 1003 (23.90/25.62)	SVSS.....WLLKSIRqlvdgnGMTAS
 1044- 1064 (24.31/11.98)	SVSGvkfliWLLVKIR......GVGSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     504.71|     160|     304|     483|     660|       4
---------------------------------------------------------------------------
  483-  660 (243.06/222.02)	KALVTGNLSVAYFSLfndLSDALMEerwIK.EVNPCLQSSLMWIGTVELSLICSiffLCEWATCDYRDCRASPSQNVKF..TGRRDLSQIHMAvsilkNKMDEMNNLSRPKSSTRIT...LNKVAKGSLNDACLTAAAVDDSSGlrSNAKNVDEKKDTNDIFEsPGPLHDiIVCWLDQHEVSNV
  800-  965 (261.64/184.26)	KALLSSLLGFTYPPL...VESKLCE...IKtSFQESVTSTLTQVETGEAKSGCE...DCMRSKGQKLDDSATPFQGFPLiqSGEEDIWWVKKG.....TKLQESFNVEPVQKSVKQTsrgRAKVVRKTQSLAQLAAARIEGSQG..ASTSHVCESKMSCPHHE.PNNDGD.NVKDFDHTRAANV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.61|      33|      63|    1379|    1411|       6
---------------------------------------------------------------------------
 1379- 1411 (52.64/39.80)	TSELSNSGKGF.VGRTAKVSAAISALVVG...AVVHG
 1441- 1477 (49.97/37.33)	TNGVSHPTGGFrIENSTEVSVHWFRILLGncrTVYDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.91|      41|      70|    1664|    1706|       7
---------------------------------------------------------------------------
 1664- 1700 (50.48/27.05)	.............................GKTTLESLRS....LSPKAEGFALSDSEKGFTEVILSRLLA
 1703- 1772 (47.13/28.42)	DAAPlyselvhllgklqeslvmdvkwilqGQDAILGRRStrqqLVHIAQRKGLSTKAQVWKPWGWSSLLS
 1773- 1834 (38.29/15.75)	DAIPnktakrklevtsieegevvddtvdaKRTTKTPPHS....VDRSFEG..IRSINKYLTEKALAEL..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.02|      38|     433|    1164|    1208|      12
---------------------------------------------------------------------------
 1164- 1208 (54.44/45.71)	AELD.NGRSIDGDlvsssGilAGEEIDEQVRQ.KLNGRSSRLVQNMK
 1598- 1637 (58.58/33.35)	AIIDcNTPTIQGD.....G..ASEPCDPKDNElKLSERLMQLLDTLQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09843 with Med12 domain of Kingdom Viridiplantae
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