<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09817

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMDPAAAALGAVPAAGAPPPGAAAGDQQAAPRVERLSAGVQQQLNLEGMRARAVGLYKAISRILEDFDVIIRTNPSASPKWQDVLGQFSMVSMELFNIVEDIKNVSKVFVVYPRNVNAENATILPVMLSSKLLPEMEVEETTKREQLLSGITNLPVPTQIEKLKVRIDMIGSACETAEKVIAECRKSYGLGSRQGTNLGPTLDKAQAAKIQEQEGLLRAAVNYGEGLRVPGDQRHPQSLPIHLIEVLPLGDGAQNFGDSSGSYPKNMSTFAPNSVNSQGNQIQASGGQLLGRPAPSPGTTGTPNFENVSTPPMPYANSPRSGTNMMNTPSPQQHLTPQQQRQKLMQHSQPLHQPVRPSAAGMLAQSALPQLQDLQGQAQQKLQVPGQQQMQYNQALSQQFHNRQMQPGRMQPGMAQSQLNQGTQLRSHLGQFTGAANNAMFNAAQASSNSQMMANMHGSQSLMPQMQYGMAGGHPHRSHPQMLTDQMFGMGATNSSMMGMQQQQQGLYGNMQAGAQNVPQGMAGLQNQTQNPNFTQQRQQNQQ
Length542
PositionHead
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.04
Grand average of hydropathy-0.570
Instability index53.11
Isoelectric point9.13
Molecular weight58519.50
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09817
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.01|      20|      23|     181|     201|       1
---------------------------------------------------------------------------
  181-  201 (31.68/23.13)	AECRKSYGLgSRQGTNLGPTL
  207-  226 (33.33/19.22)	AKIQEQEGL.LRAAVNYGEGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     343.62|      52|      53|     328|     379|       2
---------------------------------------------------------------------------
  229-  261 (36.60/ 7.06)	...........PGD.QRH..PQ.........SLPIH....LiEV.L..PLGDG.......AQN.....FGD.SSGS..
  270-  316 (34.81/ 6.39)	............AP.NS..VNSQGNQIQASGGQLLG....R.PApS..PGTTGTpnfenVSTPPMPY.AN........
  328-  378 (85.35/25.24)	...........PSP.QQHLTPQQQRQKLMQHSQPLH....Q.PV.R..PSAAGM.....LAQSALPQ.LQD.LQGQAQ
  379-  429 (54.38/13.69)	Q......klqvPG..QQQMQYNQAL......SQQFHnrqmQ.PG.RmqP...GM......AQSQLNQ.GTQ.LRSHLG
  430-  491 (60.89/16.11)	QftgaannamfNAA.QA..SSNSQMMANMHGSQSLM....P.QM.Q..YGMAGG.....HPHRSHPQmLTDqMFGMGA
  492-  541 (71.59/20.11)	T.............nSSMMGMQQQQQGLYGNMQAGA....Q.NV.P..QGMAGL.....QNQTQNPN.FTQ.QRQQNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09817 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GDGAQNFGDSSGSYPKNMSTFAPNSVNSQGNQIQASGGQLLGRPAPSPGTTGTPNFENVSTPPMPYANSPRSGTNMMNTPSPQQHLTPQQQRQKLMQHSQPLHQPVRPSAAGMLAQSALPQLQDLQGQAQQKLQVPGQQQMQYNQALSQQFHNRQMQPGRMQPGMAQSQLNQGTQLRSHLGQFTGAANNAMFNAAQASSNSQMMANMHGSQSLMPQMQYGMAGGHPHRSHPQMLTDQMFGMGATNSSMMGMQQQQQGLYGNMQAGAQNVPQGMAGLQNQTQNPNFTQQRQQNQQ
249
542










Molecular Recognition Features






MoRF SequenceStartStop




NANANA