<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09815

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMNIAVLPVMLSSKLLPEMEVEETTKREQLLSGITNLPVPTQIEKLKVRIDMIGSACETAEKVIAECRKSYGLGSRQGTNLGPTLDKAQAAKIQEQEGLLRAAVNYGEGLRVPGDQRHPQSLPIHLIEVLPLGDGAQNFGDSSGSYPKNMSTFAPNSVNSQGNQIQASGGQLLGRPAPSPGTTGTPNFENVSTPPMPYANSPRSGTNMMNTPSPQQHLTPQQQRQKLMQHSQPLHQPVRPSAAGMLAQVPGQQQMQYNQALSQQFHNRQMQPGRMQPGMAQSQLNQGTQLRSHLGQFTGAANNAMFNAAQASSNSQMMANMHGSQSLMPQMQSVFPFALVDRQERHDFLITEGAVYNIKIAEFVAFVFALSCFRTVSFFAHNFLYLMCCFIIISQYGMAGGHPHRSHPQMLTDQMFGMGATNSSMMGMQQQQQGLYGNMQAGAQNVPQGMAGLQNQTQNPNFTQQRQQNQQ
Length470
PositionHead
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.493
Instability index53.25
Isoelectric point8.95
Molecular weight51458.84
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants
GO - Biological Function
GO - Biological Process
defense response to fungus	GO:0050832	IEA:EnsemblPlants
regulation of flower development	GO:0009909	IEA:EnsemblPlants

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP09815
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     386.01|      69|     207|     190|     258|       1
---------------------------------------------------------------------------
   70-  149 (57.03/17.00)	......YGLG.....SRQGTNL..GPTLDKAQAAKiqeqegllraavnygeglrvPGDQRH...PQSLPIHLiEVLPLGDG....AQN..FG.DSSGSYPK..nM
  150-  190 (34.82/ 7.64)	STFAPNSVNSqgnqiQASGGQL..LGRPAPSPGTT....................GTPN..........................................fenV
  191-  258 (122.48/44.58)	STPPMPYANS.....PRSGTNM..MNTPSPQQHLT....................PQQQRQKLMQHSQPLHQ.PVRPSAAGML..AQV..PG.QQQMQYNQ....
  266-  316 (45.73/12.24)	....................NR..QMQPGRMQPGM....................AQSQLNQGTQLRSHLGQ.FTGAANNAMFnaAQA..SS.NSQM........
  317-  366 (42.60/10.92)	....M..ANM.....HGSQSLMpqMQSVFPFA.LV....................DRQERHDFLITEGAVYN..IK..IAEFV..AFV.................
  405-  469 (83.35/28.09)	SHPQM..LTD.....QMFG..M..GATNSS..MMG....................MQQQQQGLYGNMQAGAQ.NVPQGMAGLQ..NQTqnPNfTQQRQQNQ....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.42|      10|      16|     367|     376|       2
---------------------------------------------------------------------------
  367-  376 (18.12/11.34)	FALSCFRTVS
  384-  393 (20.30/13.41)	YLMCCFIIIS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP09815 with Med8 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GDGAQNFGDSSGSYPKNMSTFAPNSVNSQGNQIQASGGQLLGRPAPSPGTTGTPNFENVSTPPMPYANSPRSGTNMMNTPSPQQHLTPQQQRQKLMQHSQPLHQPVRPSAAGMLAQVPGQQQMQYNQALSQQFHNRQMQPGRMQPGMAQSQLNQGTQLRSH
132
292

Molecular Recognition Features

MoRF SequenceStartStop
NANANA