<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09814

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMDPAAAALGAVPAAGAPPPGAAAGDQQAAPRVERLSAGVQQQLNLEGMRARAVGLYKAISRILEDFDVIIRTNPSASPKWQDVLGQFSMVSMELFNIVEDIKNVSKVFVVYPRNVNAENATILPVMLSSKLLPEMEVEETTKREQLLSGITNLPVPTQIEKLKVRIDMIGSACETAEKVIAECRKSYGLGSRQGTNLGPTLDKAQAAKIQEQEGLLRAAVNYGEGLRVPGDQRHPQSLPIHLIEVLPLGDGAQNFGDSSGSYPKNMSTFAPNSVNSQGNQIQASGGQLLGRPAPSPGTTGTPNFENVSTPPMPYANSPRSGTNMMNTPSPQQHLTPQQQRQKLMQHSQPLHQPVRPSAAGMLAQVPGQQQMQYNQALSQQFHNRQMQPGRMQPGMAQSQLNQGTQLRSHLGQFTGAANNAMFNAAQASSNSQMMANMHGSQSLMPQMQSVFPFALVDRQERHDFLITEGAVYNIKIAEFVAFVFALSCFRTVSFFAHNFLYLMCCFIIISQYGMAGGHPHRSHPQMLTDQMFGMGATNSSMMGMQQQQQGLYGNMQAGAQNVPQGMAGLQNQTQNPNFTQQRQQNQQ
Length587
PositionHead
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.401
Instability index49.50
Isoelectric point8.72
Molecular weight63872.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
defense response to fungus	GO:0050832	IEA:EnsemblPlants
regulation of flower development	GO:0009909	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09814
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     386.01|      69|     207|     307|     375|       1
---------------------------------------------------------------------------
  187-  266 (57.03/17.33)	......YGLG.....SRQGTNL..GPTLDKAQAAKiqeqegllraavnygeglrvPGDQRH...PQSLPIHLiEVLPLGDG....AQN..FG.DSSGSYPK..nM
  267-  307 (34.82/ 7.92)	STFAPNSVNSqgnqiQASGGQL..LGRPAPSPGTT....................GTPN..........................................fenV
  308-  375 (122.48/45.06)	STPPMPYANS.....PRSGTNM..MNTPSPQQHLT....................PQQQRQKLMQHSQPLHQ.PVRPSAAGML..AQV..PG.QQQMQYNQ....
  383-  433 (45.73/12.55)	....................NR..QMQPGRMQPGM....................AQSQLNQGTQLRSHLGQ.FTGAANNAMFnaAQA..SS.NSQM........
  434-  483 (42.60/11.22)	....M..ANM.....HGSQSLMpqMQSVFPFA.LV....................DRQERHDFLITEGAVYN..IK..IAEFV..AFV.................
  522-  586 (83.35/28.48)	SHPQM..LTD.....QMFG..M..GATNSS..MMG....................MQQQQQGLYGNMQAGAQ.NVPQGMAGLQ..NQTqnPNfTQQRQQNQ....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.42|      10|      16|     484|     493|       2
---------------------------------------------------------------------------
  484-  493 (18.12/11.63)	FALSCFRTVS
  501-  510 (20.30/13.76)	YLMCCFIIIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09814 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GDGAQNFGDSSGSYPKNMSTFAPNSVNSQGNQIQASGGQLLGRPAPSPGTTGTPNFENVSTPPMPYANSPRSGTNMMNTPSPQQHLTPQQQRQKLMQHSQPLHQPVRPSAAGMLAQVPGQQQMQYNQALSQQFHNRQMQPGRMQPGMAQSQLNQGTQLRSH
249
409










Molecular Recognition Features






MoRF SequenceStartStop




NANANA